Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

Autoinhibited structure

Activated structure

1 structures for Q9SRE4

Entry ID Method Resolution Chain Position Source
AF-Q9SRE4-F1 Predicted AlphaFoldDB

8 variants for Q9SRE4

Variant ID(s) Position Change Description Diseaes Association Provenance
tmp_1_28774521_C_A 17 A>S No 1000Genomes
tmp_1_28774479_C_T 31 A>T No 1000Genomes
tmp_1_28774445_C_T 42 G>D No 1000Genomes
tmp_1_28774292_T_C 62 M>V No 1000Genomes
ENSVATH13820269 185 V>I No 1000Genomes
ENSVATH13820267 208 F>L No 1000Genomes
ENSVATH05156448 222 Q>K No 1000Genomes
tmp_1_28773339_C_G 227 A>P No 1000Genomes

No associated diseases with Q9SRE4

1 regional properties for Q9SRE4

Type Name Position InterPro Accession
domain Sugar phosphate transporter domain 25 - 299 IPR004853

Functions

Description
EC Number
Subcellular Localization
  • Golgi apparatus membrane ; Multi-pass membrane protein
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

3 GO annotations of cellular component

Name Definition
Golgi apparatus A membrane-bound cytoplasmic organelle of the endomembrane system that further processes the core oligosaccharides (e.g. N-glycans) added to proteins in the endoplasmic reticulum and packages them into membrane-bound vesicles. The Golgi apparatus operates at the intersection of the secretory, lysosomal, and endocytic pathways.
Golgi membrane The lipid bilayer surrounding any of the compartments of the Golgi apparatus.
integral component of membrane The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.

6 GO annotations of molecular function

Name Definition
antiporter activity Enables the active transport of a solute across a membrane by a mechanism whereby two or more species are transported in opposite directions in a tightly coupled process not directly linked to a form of energy other than chemiosmotic energy. The reaction is: solute A(out) + solute B(in) = solute A(in) + solute B(out).
GDP-fucose transmembrane transporter activity Enables the transfer of a GDP-fucose from one side of a membrane to the other. GDP-fucose is a substance composed of fucose in glycosidic linkage with guanosine diphosphate.
nucleotide-sugar transmembrane transporter activity Enables the transfer of a nucleotide-sugar from one side of a membrane to the other. A nucleotide-sugar is any nucleotide in which the distal phosphoric residue of a nucleoside 5'-diphosphate is in glycosidic linkage with a monosaccharide or monosaccharide derivative.
transmembrane transporter activity Enables the transfer of a substance, usually a specific substance or a group of related substances, from one side of a membrane to the other.
UDP-galactose transmembrane transporter activity Enables the transfer of a UDP-galactose from one side of a membrane to the other. UDP-galactose is a substance composed of galactose in glycosidic linkage with uridine diphosphate.
UDP-glucose transmembrane transporter activity Enables the transfer of a UDP-glucose from one side of a membrane to the other. UDP-glucose is a substance composed of glucose in glycosidic linkage with uridine diphosphate.

6 GO annotations of biological process

Name Definition
carbohydrate transport The directed movement of carbohydrate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Carbohydrates are a group of organic compounds based of the general formula Cx(H2O)y.
GDP-fucose transmembrane transport The directed movement of GDP-fucose into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. GDP-fucose is a substance composed of fucose in glycosidic linkage with guanosine diphosphate.
plant-type primary cell wall biogenesis A cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of cellulose and pectin-containing cell walls that form adjacent to the middle lamella following cell division and during cell expansion. An example of this is found in Arabidopsis thaliana.
response to nematode Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from a nematode.
UDP-galactose transmembrane transport The process in which UDP-galactose is transported across a membrane.
UDP-glucose transmembrane transport The process in which UDP-glucose is transported across a membrane.

8 homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
P0CK97 SLC35E2A Solute carrier family 35 member E2A Homo sapiens (Human) PR
Q96K37 SLC35E1 Solute carrier family 35 member E1 Homo sapiens (Human) PR
P0CK96 SLC35E2B Solute carrier family 35 member E2B Homo sapiens (Human) PR
Q8C811 Slc35e2a Solute carrier family 35 member E2A Mus musculus (Mouse) PR
Q8CD26 Slc35e1 Solute carrier family 35 member E1 Mus musculus (Mouse) PR
Q8H0T6 PPT2 Phosphoenolpyruvate/phosphate translocator 2, chloroplastic Arabidopsis thaliana (Mouse-ear cress) PR
Q9SS40 At3g10290 Probable sugar phosphate/phosphate translocator At3g10290 Arabidopsis thaliana (Mouse-ear cress) PR
Q8RXL8 UXT3 UDP-xylose transporter 3 Arabidopsis thaliana (Mouse-ear cress) PR
10 20 30 40 50 60
MEKPESEKKS AVSDVGAWAM NVISSVGIIM ANKQLMSSSG FGFGFATTLT GFHFAFTALV
70 80 90 100 110 120
GMVSNATGLS ASKHVPLWEL LWFSIVANIS IAAMNFSLML NSVGFYQISK LSMIPVVCVL
130 140 150 160 170 180
EWILHSKHYC KEVKASVMVV VIGVGICTVT DVKVNAKGFI CACTAVFSTS LQQISIGSLQ
190 200 210 220 230 240
KKYSVGSFEL LSKTAPIQAI SLLICGPFVD YLLSGKFIST YQMTYGAIFC ILLSCALAVF
250 260 270 280 290 300
CNISQYLCIG RFSATSFQVL GHMKTVCVLT LGWLLFDSEM TFKNIAGMAI AIVGMVIYSW
310 320 330 340
AVDIEKQRNA KSTPHGKHSM TEDEIKLLKE GVEHIDLKDV ELGDTKP