Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

Autoinhibited structure

Activated structure

1 structures for Q8H0T6

Entry ID Method Resolution Chain Position Source
AF-Q8H0T6-F1 Predicted AlphaFoldDB

19 variants for Q8H0T6

Variant ID(s) Position Change Description Diseaes Association Provenance
ENSVATH02102416 23 T>I No 1000Genomes
ENSVATH02102414 28 L>W No 1000Genomes
ENSVATH13856202 32 S>N No 1000Genomes
tmp_3_218748_A_T 37 S>T No 1000Genomes
ENSVATH05753239 39 N>K No 1000Genomes
ENSVATH13856201 40 S>A No 1000Genomes
tmp_3_218714_C_A 48 R>I No 1000Genomes
tmp_3_218692_C_A 55 K>N No 1000Genomes
ENSVATH13856200 60 P>S No 1000Genomes
tmp_3_218609_A_G 83 F>S No 1000Genomes
ENSVATH10450787 108 A>T No 1000Genomes
ENSVATH05753236 125 M>I No 1000Genomes
ENSVATH13856199 150 A>V No 1000Genomes
tmp_3_217989_C_T 194 S>N No 1000Genomes
ENSVATH00300783 300 M>I No 1000Genomes
ENSVATH05753223 301 S>C No 1000Genomes
tmp_3_217382_C_T 306 V>I No 1000Genomes
ENSVATH02102407 352 P>S No 1000Genomes
tmp_3_216949_A_C 384 S>G No 1000Genomes

No associated diseases with Q8H0T6

1 regional properties for Q8H0T6

Type Name Position InterPro Accession
domain Sugar phosphate transporter domain 21 - 294 IPR004853

Functions

Description
EC Number
Subcellular Localization
  • Plastid, chloroplast membrane ; Multi-pass membrane protein
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

3 GO annotations of cellular component

Name Definition
chloroplast membrane Either of the lipid bilayers that surround a chloroplast and form the chloroplast envelope.
Golgi apparatus A membrane-bound cytoplasmic organelle of the endomembrane system that further processes the core oligosaccharides (e.g. N-glycans) added to proteins in the endoplasmic reticulum and packages them into membrane-bound vesicles. The Golgi apparatus operates at the intersection of the secretory, lysosomal, and endocytic pathways.
integral component of membrane The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.

3 GO annotations of molecular function

Name Definition
antiporter activity Enables the active transport of a solute across a membrane by a mechanism whereby two or more species are transported in opposite directions in a tightly coupled process not directly linked to a form of energy other than chemiosmotic energy. The reaction is: solute A(out) + solute B(in) = solute A(in) + solute B(out).
phosphoenolpyruvate:phosphate antiporter activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: phosphoenolpyruvate(out) + phosphate(in) = phosphoenolpyruvate(in) + phosphate(out).
phosphoglycerate transmembrane transporter activity Enables the transfer of phosphoglycerates from one side of a membrane to the other. Phosphoglycerates are important intermediates in glycolysis and 3-phosphoglycerate is a precursor in serine biosynthesis.

3 GO annotations of biological process

Name Definition
carbohydrate transport The directed movement of carbohydrate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Carbohydrates are a group of organic compounds based of the general formula Cx(H2O)y.
phosphoenolpyruvate transport The directed movement of phosphoenolpyruvate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
phosphoglycerate transmembrane transport The process in which phosphoglycerate is transported across a lipid bilayer, from one side of a membrane to the other.

8 homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
P0CK97 SLC35E2A Solute carrier family 35 member E2A Homo sapiens (Human) PR
P0CK96 SLC35E2B Solute carrier family 35 member E2B Homo sapiens (Human) PR
Q96K37 SLC35E1 Solute carrier family 35 member E1 Homo sapiens (Human) PR
Q8C811 Slc35e2a Solute carrier family 35 member E2A Mus musculus (Mouse) PR
Q8CD26 Slc35e1 Solute carrier family 35 member E1 Mus musculus (Mouse) PR
Q8RXL8 UXT3 UDP-xylose transporter 3 Arabidopsis thaliana (Mouse-ear cress) PR
Q9SRE4 URGT1 UDP-rhamnose/UDP-galactose transporter 1 Arabidopsis thaliana (Mouse-ear cress) PR
Q9SS40 At3g10290 Probable sugar phosphate/phosphate translocator At3g10290 Arabidopsis thaliana (Mouse-ear cress) PR
10 20 30 40 50 60
MFALTFLNPN PRLPSPLFLA KSTPESALSR RSRAFSSSNS YPWRPNLRFN GFKLKSATVP
70 80 90 100 110 120
ENVEGGDLES GSLVKGLKLG GMFGVWYLLN IYYNIFNKQV LRVYPYPATV TAFQLGCGTL
130 140 150 160 170 180
MIAIMWLLKL HPRPKFSPSQ FTVIVQLAVA HTLGNLLTNV SLGRVNVSFT HTIKAMEPFF
190 200 210 220 230 240
TVLLSVLLLG EWPSLWIVCS LLPIVAGVSL ASFTEASFNW IGFCSAMASN VTNQSRNVLS
250 260 270 280 290 300
KKFMVGKDAL DNINLFSIIT IISFILLVPL AILIDGFKVT PSHLQVATSQ GLSVKEFCIM
310 320 330 340 350 360
SLLAGVCLHS YQQVSYMILE MVSPVTHSVG NCVKRVVVIT SSILFFKTPV SPLNSIGTAT
370 380
ALAGVYLYSR AKRVQVKPNP KMS