AiPD: Autoinhibited Protein Database

Q96K37

Gene name	SLC35E1 (PSEC0038)
Protein name	Solute carrier family 35 member E1
Names
Species	Homo sapiens (Human)
KEGG Pathway	hsa:79939
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

318-399 (Predicted disordered autoinhibitory region) PR

Target domain
Relief mechanism
Assay	cis-regPred

AID

318-399 (Predicted disordered autoinhibitory region)

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Yeon JH et al. (2016) "Systems-wide Identification of cis-Regulatory Elements in Proteins", Cell Systems, 2, 89-100

Autoinhibited structure

Activated structure

1 structures for Q96K37

Entry ID	Method	Resolution	Chain	Position	Source
AF-Q96K37-F1	Predicted				AlphaFoldDB

298 variants for Q96K37

Variant ID(s)	Position	Change	Description	Diseaes Association	Provenance
CA404598003 rs1394995011	2	A>V		No	ClinGen TOPMed
CA404597987 rs1393696965	4	A>S		No	ClinGen TOPMed
CA404597930 rs1036482002	6	V>E		No	ClinGen gnomAD
rs1036482002 CA305955970	6	V>G		No	ClinGen gnomAD
CA404597949 rs1285447227	6	V>L		No	ClinGen TOPMed
CA305955964 rs937268057	8	A>P		No	ClinGen TOPMed
rs1205836570 CA404597888	9	G>C		No	ClinGen TOPMed
rs1267555839 CA404597873	10	H>R		No	ClinGen TOPMed
CA404597843 rs1201050401	12	A>V		No	ClinGen TOPMed
CA404597840 rs1434071608	13	G>R		No	ClinGen TOPMed
CA305955963 rs928533552	14	G>A		No	ClinGen TOPMed gnomAD
CA404597803 rs928533552	14	G>D		No	ClinGen TOPMed gnomAD
CA404597814 rs1466819378	14	G>S		No	ClinGen TOPMed gnomAD
rs1395432468 CA404597791	15	P>L		No	ClinGen gnomAD
CA305955962 rs981702692	15	P>S		No	ClinGen TOPMed gnomAD
CA9280301 rs775722955	17	A>T		No	ClinGen ExAC TOPMed gnomAD
rs1403187197 CA404597725	20	S>N		No	ClinGen TOPMed
rs1412993153 CA404597712	21	S>G		No	ClinGen gnomAD
CA404597709 rs1305145017	21	S>N		No	ClinGen TOPMed
rs1381917744 CA404597620	25	R>H		No	ClinGen TOPMed
TCGA novel	26	E>*	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA404597604 rs989936448	26	E>K		No	ClinGen TOPMed gnomAD
rs989936448 CA305955926	26	E>Q		No	ClinGen TOPMed gnomAD
CA404597535 rs1468657889	28	A>T		No	ClinGen gnomAD
CA305955924 rs957099444	28	A>V		No	ClinGen TOPMed gnomAD
CA9280300 rs770045689	33	L>V		No	ClinGen ExAC TOPMed gnomAD
rs868497946 CA305955913	34	C>F		No	ClinGen Ensembl
CA305955900 rs953628264	37	W>C		No	ClinGen TOPMed
CA404597270 rs1342064193	39	A>S		No	ClinGen gnomAD
rs1372008165 CA404597218	42	A>P		No	ClinGen gnomAD
CA404597188 rs1220846427	44	G>A		No	ClinGen TOPMed gnomAD
CA305955877 rs866698867	46	V>L		No	ClinGen gnomAD
rs866698867 CA404597160	46	V>M		No	ClinGen gnomAD
CA404597135 rs1349438765	47	V>A		No	ClinGen gnomAD
CA305955873 rs898016411	47	V>I		No	ClinGen TOPMed gnomAD
CA404596921 rs1388189629	60	T>I		No	ClinGen gnomAD
rs865863690 CA305955868	60	T>P		No	ClinGen Ensembl
rs1396518959 CA404596898	61	V>E		No	ClinGen gnomAD
CA404596900 rs1454498406 CA404596907	61	V>L		No	ClinGen gnomAD
rs1015505617 CA305955837	65	H>Q		No	ClinGen TOPMed
CA9280298 rs781026728	66	I>V		No	ClinGen ExAC TOPMed gnomAD
CA404596755 rs1440088763	69	L>V		No	ClinGen gnomAD
CA404596730 rs1204910983	71	A>T		No	ClinGen TOPMed gnomAD
CA305955814 rs77915538	73	L>P		No	ClinGen Ensembl
CA305955810 rs887829336	74	P>L		No	ClinGen TOPMed
TCGA novel	74	P>R	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs1248132587 CA404596641	75	P>R		No	ClinGen TOPMed
CA404596602 rs1174911220	78	R>S		No	ClinGen Ensembl
CA404596587 rs1599324204	79	A>T		No	ClinGen Ensembl
rs1402810083 CA404596527	81	R>G		No	ClinGen gnomAD
CA404596481 rs1315871221	83	P>S		No	ClinGen TOPMed
rs1568276177 CA404596450	85	A>T		No	ClinGen Ensembl
CA404596360 rs1307273813	89	S>L		No	ClinGen gnomAD
rs201579767 CA305955799	90	G>R		No	ClinGen TOPMed gnomAD
CA305955797 rs201579767	90	G>S		No	ClinGen TOPMed gnomAD
CA404596350 rs1045679673	91	P>A		No	ClinGen TOPMed gnomAD
CA305955791 rs1045679673	91	P>S		No	ClinGen TOPMed gnomAD
CA404596328 rs1408212762	92	G>*		No	ClinGen TOPMed gnomAD
rs577323650 CA9280296	92	G>E		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
CA404596329 CA404596333 rs1408212762	92	G>R		No	ClinGen TOPMed gnomAD
rs1250410859 CA404596315	93	P>H		No	ClinGen gnomAD
CA404596318 rs1468106450	93	P>S		No	ClinGen gnomAD
rs1486266504 CA404596306	94	S>G		No	ClinGen gnomAD
TCGA novel	94	S>N	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA404596268 rs1157137898	95	P>L		No	ClinGen TOPMed
rs1458007330 CA404596264	96	H>D		No	ClinGen TOPMed
CA404596259 rs557296600	96	H>L		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
CA404596260 rs557296600	96	H>P		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
CA9280295 rs557296600	96	H>R		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
CA9280294 rs757953755	98	S>L		No	ClinGen ExAC gnomAD
rs1284722091 CA404596225	98	S>P		No	ClinGen TOPMed
CA9280293 rs752186866	99	S>F		No	ClinGen ExAC gnomAD
CA404596163 rs1308635655	101	P>L		No	ClinGen TOPMed
rs1348768467 CA404596179	101	P>T		No	ClinGen gnomAD
CA404596154 rs1178907900	102	L>Q		No	ClinGen TOPMed gnomAD
CA404596100 rs1300902325	105	P>L		No	ClinGen TOPMed gnomAD
CA404596097 rs1300902325	105	P>Q		No	ClinGen TOPMed gnomAD
CA404596098 rs1300902325	105	P>R		No	ClinGen TOPMed gnomAD
rs935736929 CA305955781	106	R>C		No	ClinGen TOPMed
CA404596091 rs1480028056	106	R>H		No	ClinGen Ensembl
CA404596071 rs1465301555	107	F>S		No	ClinGen gnomAD
rs764959391 CA9280292	108	Y>S		No	ClinGen ExAC gnomAD
rs1160913186 CA404595974	112	V>M		No	ClinGen gnomAD
rs1410634210 CA404595937	114	P>L		No	ClinGen TOPMed gnomAD
rs750812338 TCGA novel CA9280290	117	F>L	Variant assessed as Somatic; impact. [NCI-TCGA]	No	ClinGen ExAC TOPMed gnomAD NCI-TCGA
CA404595870 rs1258822687	118	G>C		No	ClinGen gnomAD
CA404595809 rs1180483745	121	F>V		No	ClinGen gnomAD
TCGA novel	125	S>L	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs575018623 CA9280288	128	V>I		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
rs1218262910 CA404595701	129	S>G		No	ClinGen gnomAD
TCGA novel	130	I>M	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA404595660 rs1327316575	131	W>R		No	ClinGen gnomAD
CA305955748 rs1029722751	133	V>A		No	ClinGen TOPMed
CA404595602 rs1176049737	133	V>L		No	ClinGen TOPMed
rs868723130 CA404595584	134	P>S		No	ClinGen gnomAD
CA305955742 rs868723130	134	P>T		No	ClinGen gnomAD
rs1336869370 CA404595500	141	V>I		No	ClinGen gnomAD
rs778572274 CA9280273	144	T>N		No	ClinGen ExAC TOPMed gnomAD
CA404593564 rs1170883231	145	M>V		No	ClinGen gnomAD
rs1389934325 CA404593535	149	V>M		No	ClinGen TOPMed gnomAD
CA9280270 rs767971575	151	L>F	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen ExAC NCI-TCGA TOPMed gnomAD
CA9280269 rs757679561	151	L>P		No	ClinGen ExAC TOPMed gnomAD
rs1480934382 CA404593509	153	S>F		No	ClinGen gnomAD
CA404593508 rs1202779639	154	R>G		No	ClinGen gnomAD
rs1000093968 CA305955413	155	I>T		No	ClinGen TOPMed
CA9280266 rs763380382	155	I>V		No	ClinGen ExAC gnomAD
rs1236091088 CA404593473	159	E>Q		No	ClinGen gnomAD
rs775477901 CA9280265	161	Q>H		No	ClinGen ExAC TOPMed gnomAD
CA404593449 rs1230819695	162	S>C		No	ClinGen TOPMed
TCGA novel	162	S>I	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA305955410 rs889661925	162	S>N		No	ClinGen TOPMed
rs944747722 CA404593445	162	S>R		No	ClinGen gnomAD
TCGA novel	163	T>A	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA404635295 rs1381595141	165	V>I		No	ClinGen gnomAD
rs753256934 CA9280247	166	Y>C		No	ClinGen ExAC TOPMed gnomAD
CA306011182 rs745802741	171	P>A		No	ClinGen Ensembl
rs759576353 CA9280245	173	I>V		No	ClinGen ExAC TOPMed gnomAD
CA9280242 rs760813611	175	G>D		No	ClinGen ExAC gnomAD
rs766567404 CA9280243	175	G>S		No	ClinGen ExAC gnomAD
CA404635206 rs1414332355	179	A>V		No	ClinGen gnomAD
rs774469202 CA9280238	181	V>I		No	ClinGen ExAC TOPMed gnomAD
TCGA novel	186	F>L	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA404635159 rs1255216463	187	D>N		No	ClinGen gnomAD
rs941557153 CA306011147	188	M>T		No	ClinGen TOPMed gnomAD
CA9280233 rs745571318	188	M>V		No	ClinGen ExAC gnomAD
TCGA novel	189	W>*	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
TCGA novel	189	W>R	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA404635129 rs1568274955	191	L>F		No	ClinGen Ensembl
CA404635122 rs138285196	192	V>F		No	ClinGen ESP ExAC TOPMed gnomAD
CA9280231 rs138285196	192	V>I		No	ClinGen ESP ExAC TOPMed gnomAD
CA404635117 rs1450796743	193	S>G		No	ClinGen gnomAD
rs779346314 CA9280229	194	A>T		No	ClinGen ExAC gnomAD
TCGA novel	194	A>V	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs1383036699 CA404635103	195	L>F		No	ClinGen gnomAD
TCGA novel	195	L>I	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs753890960 CA9280227	196	A>T		No	ClinGen ExAC gnomAD
CA306011135 rs1055547975	196	A>V		No	ClinGen gnomAD
CA9280225 rs561883745	197	A>T		No	ClinGen 1000Genomes ExAC gnomAD
rs1471754015 CA404635086	198	T>M		No	ClinGen gnomAD
rs1568274926 CA404635067	201	F>C		No	ClinGen Ensembl
CA306011106 rs201684397	205	N>S		No	ClinGen 1000Genomes
CA9280220 rs764064028	206	I>M		No	ClinGen ExAC gnomAD
TCGA novel	210	K>R	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs1207567731 CA404635004	210	K>R		No	ClinGen gnomAD
CA9280203 rs764043868	213	R>*		No	ClinGen ExAC gnomAD
rs762967076 CA9280202	213	R>Q		No	ClinGen ExAC TOPMed gnomAD
rs1167704168 CA404634961	215	S>L		No	ClinGen gnomAD
rs758925004 CA9280199	216	R>Q	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen ExAC NCI-TCGA TOPMed gnomAD
rs765255227 CA9280200	216	R>W	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen ExAC NCI-TCGA TOPMed gnomAD
CA9280198 rs776222129	221	R>Q		No	ClinGen ExAC TOPMed gnomAD
rs1183587950 CA404634909	224	N>S		No	ClinGen gnomAD
CA306010239 rs377141552	228	C>F		No	ClinGen ESP
rs967033576 CA306010241	228	C>R		No	ClinGen Ensembl
rs769059037 CA9280194	230	A>T		No	ClinGen ExAC gnomAD
CA306010217 rs201250256	231	V>F		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
rs201250256 CA9280192	231	V>I		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
rs540729933 CA9280191	232	F>V		No	ClinGen 1000Genomes ExAC gnomAD
rs1344481248 CA404634851	233	F>L		No	ClinGen gnomAD
rs1289028995 CA404634848	234	M>V		No	ClinGen gnomAD
rs1411639337 CA404634824	237	T>I		No	ClinGen gnomAD
CA404634819 rs1348502642	238	W>G		No	ClinGen gnomAD
CA404634821 rs1348502642	238	W>R		No	ClinGen gnomAD
rs745876227 CA9280190	240	L>V		No	ClinGen ExAC gnomAD
rs909031994 CA306010203	241	V>M		No	ClinGen TOPMed
CA404634780 rs1448411460	244	S>*		No	ClinGen TOPMed gnomAD
rs1448411460 CA404634778	244	S>L		No	ClinGen TOPMed gnomAD
TCGA novel	245	A>V	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs1407253136 CA404634767	246	F>S		No	ClinGen TOPMed
CA9280188 rs375432387	248	V>A		No	ClinGen ESP ExAC TOPMed gnomAD
CA9280187 rs375432387	248	V>D		No	ClinGen ESP ExAC TOPMed gnomAD
CA404634751 rs1412133109	249	S>N		No	ClinGen gnomAD
rs752563576 CA9280184	251	D>E		No	ClinGen ExAC gnomAD
rs140736951 CA9280185	251	D>N		No	ClinGen ESP ExAC TOPMed gnomAD
rs765030120 CA9280183	252	L>F		No	ClinGen ExAC gnomAD
CA404634321 rs1599315696	253	T>P		No	ClinGen Ensembl
rs984010174 CA404634302	254	Y>C		No	ClinGen TOPMed gnomAD
CA404634300 rs984010174	254	Y>F		No	ClinGen TOPMed gnomAD
CA306003168 rs984010174	254	Y>S		No	ClinGen TOPMed gnomAD
rs1208955573 CA404634289	255	V>A		No	ClinGen gnomAD
rs768784190 CA9280129	255	V>I	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen ExAC NCI-TCGA TOPMed gnomAD
rs146779841 CA9280128	256	Y>S		No	ClinGen ESP ExAC TOPMed
CA404634265 rs1465918768	257	Q>*		No	ClinGen TOPMed gnomAD
rs1203940628 CA404634245	258	W>S		No	ClinGen gnomAD
rs374298006 CA9280126	260	W>S		No	ClinGen ESP ExAC TOPMed gnomAD
rs745863119 CA9280125	261	T>M		No	ClinGen ExAC TOPMed gnomAD
CA9280123 rs756830191	266	A>T		No	ClinGen ExAC TOPMed gnomAD
CA306003119 rs749199081	269	G>S		No	ClinGen gnomAD
CA9280120 rs758132299	271	C>F		No	ClinGen ExAC gnomAD
CA404634087 rs758132299	271	C>Y		No	ClinGen ExAC gnomAD
rs754254923 CA9280119	272	N>K		No	ClinGen ExAC
rs766910485 CA9280118	274	A>S		No	ClinGen ExAC gnomAD
rs1271241992 CA404634041	274	A>V		No	ClinGen TOPMed
CA404633990 rs1194595309	278	I>T		No	ClinGen gnomAD
rs761244145 CA9280117	279	A>T		No	ClinGen ExAC gnomAD
rs1204827085 CA404633954	281	S>G		No	ClinGen TOPMed
CA306003078 rs994565393	281	S>I		No	ClinGen Ensembl
rs1204827085 CA404633955	281	S>R		No	ClinGen TOPMed
CA9280115 rs376995220	284	N>S		No	ClinGen ESP ExAC gnomAD
CA306003070 rs1020101948	286	V>I	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen NCI-TCGA TOPMed gnomAD
CA404633755 rs1212138092	292	S>L		No	ClinGen gnomAD
CA9280110 rs775250515	293	V>I		No	ClinGen ExAC gnomAD
rs745759492 CA9280108	294	A>T		No	ClinGen ExAC
CA9280107 rs140984339	295	N>S		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
CA306003037 rs1053924837	296	A>T		No	ClinGen Ensembl
CA404633707 rs1268498851	300	I>T		No	ClinGen gnomAD
rs369825827 CA9280106	301	M>I		No	ClinGen ESP ExAC gnomAD
rs1331745237 CA404633700	301	M>T		No	ClinGen gnomAD
rs1430039744 CA404633703	301	M>V		No	ClinGen gnomAD
rs1422637654 CA404633694	302	V>I		No	ClinGen gnomAD
CA9280105 rs200023824	304	T>M		No	ClinGen ExAC TOPMed gnomAD
CA9280102 rs752449991	309	M>T		No	ClinGen ExAC gnomAD
CA9280101 rs780536619	311	R>C	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen ExAC NCI-TCGA gnomAD
rs202071873 CA9280100	311	R>H		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
CA404633630 rs1232047973	312	N>K		No	ClinGen TOPMed
CA404633624 rs1295184311	313	P>L		No	ClinGen TOPMed
rs1201696533 CA404633622	314	V>F		No	ClinGen gnomAD
rs762230581 CA9280097	316	S>R		No	ClinGen ExAC gnomAD
CA9280098 rs768011105	316	S>T		No	ClinGen ExAC gnomAD
CA9280096 rs751654477	317	T>I		No	ClinGen ExAC gnomAD
rs1408146172 CA404633592	319	V>I	Variant assessed as Somatic; impact. [NCI-TCGA]	No	ClinGen NCI-TCGA gnomAD
rs1056820937 CA306002960	329	V>F		No	ClinGen TOPMed
rs1056820937 CA404633526	329	V>I		No	ClinGen TOPMed
rs937057026 CA306002945	333	N>K		No	ClinGen gnomAD
rs747605523 CA9280065	338	D>E		No	ClinGen ExAC TOPMed gnomAD
CA9280066 rs772157979	338	D>N		No	ClinGen ExAC TOPMed gnomAD
CA9280064 rs778572398	340	N>T		No	ClinGen ExAC TOPMed gnomAD
CA9280063 rs768348529	342	Q>R		No	ClinGen ExAC gnomAD
rs1290710883 CA404633416	343	A>T		No	ClinGen Ensembl
rs748949658 CA9280062	343	A>V		No	ClinGen ExAC gnomAD
CA9280061 rs151052094	344	R>G		No	ClinGen ESP ExAC TOPMed gnomAD
rs1455830780 CA404633403	345	K>R		No	ClinGen gnomAD
rs1568270602 CA404633386	347	L>P		No	ClinGen Ensembl
CA9280058 rs778199028	350	V>I		No	ClinGen ExAC gnomAD
CA306001677 rs971046024	351	T>A		No	ClinGen TOPMed
rs1439827641 CA404633363	351	T>I		No	ClinGen gnomAD
rs376710881 CA9280057	352	T>I		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
CA404633354 rs1313440234	353	A>E		No	ClinGen TOPMed gnomAD
TCGA novel	353	A>missing	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs148657007 CA9280056	354	D>E		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
CA404633343 rs1248748307	355	L>V		No	ClinGen gnomAD
rs1188317152 CA404633336	356	S>N		No	ClinGen TOPMed gnomAD
CA9280053 rs754052000	359	E>D		No	ClinGen ExAC gnomAD
rs552232039 CA9280054	359	E>K		No	ClinGen ExAC gnomAD
CA9280052 rs372456978	360	R>C		No	ClinGen ESP ExAC TOPMed gnomAD
CA9280051 rs200335570	360	R>H	Variant assessed as Somatic; 9.241e-05 impact. [NCI-TCGA]	No	ClinGen ESP ExAC NCI-TCGA TOPMed gnomAD
CA404633303 rs1289293305	361	H>Y		No	ClinGen gnomAD
CA9280049 rs147619010	362	R>Q	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen ESP ExAC NCI-TCGA TOPMed gnomAD
rs565590794 CA9280050	362	R>W	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen 1000Genomes ExAC NCI-TCGA TOPMed gnomAD
rs1379971348 CA404633292	363	S>N	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen NCI-TCGA gnomAD
rs375491945 CA9280048	363	S>R		No	ClinGen ESP ExAC TOPMed gnomAD
CA9280047 rs773984481	365	L>P		No	ClinGen ExAC gnomAD
CA404633261 rs1288867280	368	P>T		No	ClinGen gnomAD
rs748938583 CA9280045	369	H>P		No	ClinGen ExAC gnomAD
rs768099647 CA9280046	369	H>Y		No	ClinGen ExAC gnomAD
rs1390957595 CA404633239	371	G>D		No	ClinGen TOPMed gnomAD
CA9280043 rs145285238	371	G>S		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
CA404633237 rs1390957595	371	G>V		No	ClinGen TOPMed gnomAD
rs372899866 CA9280041	372	L>R		No	ClinGen ESP ExAC gnomAD
CA404633233 rs1170698223	372	L>V		No	ClinGen TOPMed
rs758896013 CA9280040	373	L>V		No	ClinGen ExAC
rs901860363 CA306001507	377	H>P		No	ClinGen TOPMed gnomAD
CA9280035 rs147350311	378	G>R		No	ClinGen ESP ExAC TOPMed gnomAD
rs1599761520 CA404633146	379	D>N		No	ClinGen Ensembl
rs750240068 CA9280033	380	Y>C		No	ClinGen ExAC gnomAD
rs767476586 CA9280032	382	Y>H		No	ClinGen ExAC gnomAD
CA404633085 rs1568270524	383	G>D		No	ClinGen Ensembl
CA9280031 rs562290843	383	G>S		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
rs199865548 CA9280030	384	R>C		No	ClinGen ESP ExAC TOPMed gnomAD
rs1347898165 CA404633076	384	R>H		No	ClinGen gnomAD
CA9280029 rs199865548	384	R>S		No	ClinGen ESP ExAC TOPMed gnomAD
CA404633064 rs1273531715	385	N>S		No	ClinGen TOPMed
rs1347822399 CA404633055	386	N>D		No	ClinGen TOPMed
rs1219885092 CA404633050	386	N>S		No	ClinGen TOPMed
rs762318321 CA404632996	390	D>A		No	ClinGen ExAC gnomAD
rs762318321 CA9280028	390	D>V		No	ClinGen ExAC gnomAD
CA404632984 rs1599761488	391	H>P		No	ClinGen Ensembl
CA404632937 rs1365562281	394	Y>*		No	ClinGen Ensembl
CA404632943 rs1200700853	394	Y>C		No	ClinGen TOPMed
CA306001378 rs371174699	396	R>Q		No	ClinGen ESP TOPMed gnomAD
rs775075153 CA9280027	396	R>W	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen ExAC NCI-TCGA gnomAD
rs1372597813 CA404632902	397	Q>*		No	ClinGen gnomAD
TCGA novel	398	S>I	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs1176828102 CA404632853	400	P>S		No	ClinGen gnomAD
CA404632840 rs1568270496	401	N>D		No	ClinGen Ensembl
CA306001365 rs867649677	402	S>L	Variant assessed as Somatic; impact. [NCI-TCGA]	No	ClinGen Ensembl NCI-TCGA
CA9280023 rs761910310	403	Y>*		No	ClinGen ESP ExAC TOPMed
CA404632803 rs1427049535	403	Y>C		No	ClinGen gnomAD
CA9280024 rs773546820	404	S>N		No	ClinGen ExAC
CA9280022 rs772468571	405	L>W		No	ClinGen ExAC TOPMed gnomAD
CA9280021 rs368062600	407	R>C		No	ClinGen ESP ExAC TOPMed gnomAD
CA9280020 rs779242527	407	R>H		No	ClinGen ExAC TOPMed gnomAD
CA404632724 rs1193767953	408	Y>C		No	ClinGen TOPMed gnomAD
rs1466761433 CA404632730	408	Y>H		No	ClinGen TOPMed
CA9280018 rs749260441	409	D>H		No	ClinGen ExAC gnomAD
CA9280019 rs749260441	409	D>N		No	ClinGen ExAC gnomAD
CA9280016 rs756393413	410	V>A		No	ClinGen ExAC gnomAD
CA9280017 rs780249386	410	V>L		No	ClinGen ExAC gnomAD
CA404632677 rs1393300747	411	V>Y	Variant assessed as Somatic; impact. [NCI-TCGA]	No	ClinGen NCI-TCGA TOPMed

No associated diseases with Q96K37

1 regional properties for Q96K37

Type	Name	Position	InterPro Accession
domain	Sugar phosphate transporter domain	29 - 333	IPR004853

Functions

		Description
EC Number
Subcellular Localization	Membrane ; Multi-pass membrane protein
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category	No pathway information available

2 GO annotations of cellular component

Name	Definition
Golgi apparatus	A membrane-bound cytoplasmic organelle of the endomembrane system that further processes the core oligosaccharides (e.g. N-glycans) added to proteins in the endoplasmic reticulum and packages them into membrane-bound vesicles. The Golgi apparatus operates at the intersection of the secretory, lysosomal, and endocytic pathways.
integral component of membrane	The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.

1 GO annotations of molecular function

Name	Definition
antiporter activity	Enables the active transport of a solute across a membrane by a mechanism whereby two or more species are transported in opposite directions in a tightly coupled process not directly linked to a form of energy other than chemiosmotic energy. The reaction is: solute A(out) + solute B(in) = solute A(in) + solute B(out).

No GO annotations of biological process

Name	Definition
No GO annotations for biological process

8 homologous proteins in AiPD

UniProt AC	Gene Name	Protein Name	Species	Evidence Code
P0CK97	SLC35E2A	Solute carrier family 35 member E2A	Homo sapiens (Human)	PR
P0CK96	SLC35E2B	Solute carrier family 35 member E2B	Homo sapiens (Human)	PR
Q8C811	Slc35e2a	Solute carrier family 35 member E2A	Mus musculus (Mouse)	PR
Q8CD26	Slc35e1	Solute carrier family 35 member E1	Mus musculus (Mouse)	PR
Q8RXL8	UXT3	UDP-xylose transporter 3	Arabidopsis thaliana (Mouse-ear cress)	PR
Q9SRE4	URGT1	UDP-rhamnose/UDP-galactose transporter 1	Arabidopsis thaliana (Mouse-ear cress)	PR
Q9SS40	At3g10290	Probable sugar phosphate/phosphate translocator At3g10290	Arabidopsis thaliana (Mouse-ear cress)	PR
Q8H0T6	PPT2	Phosphoenolpyruvate/phosphate translocator 2, chloroplastic	Arabidopsis thaliana (Mouse-ear cress)	PR

10	20	30	40	50	60
MAAAAVGAGH	GAGGPGAASS	SGGAREGARV	AALCLLWYAL	SAGGNVVNKV	ILSAFPFPVT
70	80	90	100	110	120
VSLCHILALC	AGLPPLLRAW	RVPPAPPVSG	PGPSPHPSSG	PLLPPRFYPR	YVLPLAFGKY
130	140	150	160	170	180
FASVSAHVSI	WKVPVSYAHT	VKATMPIWVV	LLSRIIMKEK	QSTKVYLSLI	PIISGVLLAT
190	200	210	220	230	240
VTELSFDMWG	LVSALAATLC	FSLQNIFSKK	VLRDSRIHHL	RLLNILGCHA	VFFMIPTWVL
250	260	270	280	290	300
VDLSAFLVSS	DLTYVYQWPW	TLLLLAVSGF	CNFAQNVIAF	SILNLVSPLS	YSVANATKRI
310	320	330	340	350	360
MVITVSLIML	RNPVTSTNVL	GMMTAILGVF	LYNKTKYDAN	QQARKHLLPV	TTADLSSKER
370	380	390	400
HRSPLEKPHN	GLLFPQHGDY	QYGRNNILTD	HFQYSRQSYP	NSYSLNRYDV