Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

Autoinhibited structure

Activated structure

1 structures for Q9SIP7

Entry ID Method Resolution Chain Position Source
AF-Q9SIP7-F1 Predicted AlphaFoldDB

5 variants for Q9SIP7

Variant ID(s) Position Change Description Diseaes Association Provenance
ENSVATH01934728 5 I>S No 1000Genomes
ENSVATH05639279 215 D>E No 1000Genomes
ENSVATH05639280 226 A>T No 1000Genomes
tmp_2_13451605_C_T 230 T>I No 1000Genomes
tmp_2_13451652_A_G 246 I>V No 1000Genomes

No associated diseases with Q9SIP7

2 regional properties for Q9SIP7

Type Name Position InterPro Accession
domain Ribosomal protein S3, C-terminal 106 - 188 IPR001351
domain K Homology domain, type 2 20 - 93 IPR004044

Functions

Description
EC Number
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

7 GO annotations of cellular component

Name Definition
chloroplast A chlorophyll-containing plastid with thylakoids organized into grana and frets, or stroma thylakoids, and embedded in a stroma.
cytosolic ribosome A ribosome located in the cytosol.
cytosolic small ribosomal subunit The small subunit of a ribosome located in the cytosol.
nucleus A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
peroxisome A small organelle enclosed by a single membrane, and found in most eukaryotic cells. Contains peroxidases and other enzymes involved in a variety of metabolic processes including free radical detoxification, lipid catabolism and biosynthesis, and hydrogen peroxide metabolism.
plant-type vacuole A closed structure that is completely surrounded by a unit membrane, contains liquid, and retains the same shape regardless of cell cycle phase. An example of this structure is found in Arabidopsis thaliana.
plasmodesma A fine cytoplasmic channel, found in all higher plants, that connects the cytoplasm of one cell to that of an adjacent cell.

2 GO annotations of molecular function

Name Definition
mRNA binding Binding to messenger RNA (mRNA), an intermediate molecule between DNA and protein. mRNA includes UTR and coding sequences, but does not contain introns.
structural constituent of ribosome The action of a molecule that contributes to the structural integrity of the ribosome.

1 GO annotations of biological process

Name Definition
translation The cellular metabolic process in which a protein is formed, using the sequence of a mature mRNA or circRNA molecule to specify the sequence of amino acids in a polypeptide chain. Translation is mediated by the ribosome, and begins with the formation of a ternary complex between aminoacylated initiator methionine tRNA, GTP, and initiation factor 2, which subsequently associates with the small subunit of the ribosome and an mRNA or circRNA. Translation ends with the release of a polypeptide chain from the ribosome.

7 homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
P05750 RPS3 40S ribosomal protein S3 Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) PR
Q06559 RpS3 40S ribosomal protein S3 Drosophila melanogaster (Fruit fly) PR
P23396 RPS3 40S ribosomal protein S3 Homo sapiens (Human) PR
P62908 Rps3 40S ribosomal protein S3 Mus musculus (Mouse) PR
P48152 rps-3 40S ribosomal protein S3 Caenorhabditis elegans PR
Q9FJA6 RPS3C 40S ribosomal protein S3-3 Arabidopsis thaliana (Mouse-ear cress) PR
Q9M339 RPS3B 40S ribosomal protein S3-2 Arabidopsis thaliana (Mouse-ear cress) PR
10 20 30 40 50 60
MATQISKKRK FVADGVFYAE LNEVLTRELA EDGYSGVEVR VTPMRTEIII RATRTQNVLG
70 80 90 100 110 120
EKGRRIRELT SLVQKRFKFP VDSVELYAEK VNNRGLCAIA QAESLRYKLL GGLAVRRACY
130 140 150 160 170 180
GVLRFVMESG AKGCEVIVSG KLRAARAKSM KFKDGYMVSS GQPTKEYIDA AVRHVLLRQG
190 200 210 220 230 240
VLGIKVKIML DWDPTGKSGP KTPLPDVVII HAPKDDVVYS APAQAAAPVT LVQEAPLTTV
DYPEMIPPVA