Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

Autoinhibited structure

Activated structure

1 structures for P48152

Entry ID Method Resolution Chain Position Source
AF-P48152-F1 Predicted AlphaFoldDB

No variants for P48152

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for P48152

No associated diseases with P48152

3 regional properties for P48152

Type Name Position InterPro Accession
domain Ribosomal protein S3, C-terminal 108 - 190 IPR001351
domain K Homology domain, type 2 22 - 95 IPR004044
conserved_site Ribosomal protein S3, conserved site 149 - 185 IPR018280

Functions

Description
EC Number
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

2 GO annotations of cellular component

Name Definition
cytosolic small ribosomal subunit The small subunit of a ribosome located in the cytosol.
nucleus A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.

2 GO annotations of molecular function

Name Definition
RNA binding Binding to an RNA molecule or a portion thereof.
structural constituent of ribosome The action of a molecule that contributes to the structural integrity of the ribosome.

2 GO annotations of biological process

Name Definition
positive regulation of apoptotic signaling pathway Any process that activates or increases the frequency, rate or extent of apoptotic signaling pathway.
translation The cellular metabolic process in which a protein is formed, using the sequence of a mature mRNA or circRNA molecule to specify the sequence of amino acids in a polypeptide chain. Translation is mediated by the ribosome, and begins with the formation of a ternary complex between aminoacylated initiator methionine tRNA, GTP, and initiation factor 2, which subsequently associates with the small subunit of the ribosome and an mRNA or circRNA. Translation ends with the release of a polypeptide chain from the ribosome.

7 homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
P05750 RPS3 40S ribosomal protein S3 Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) PR
Q06559 RpS3 40S ribosomal protein S3 Drosophila melanogaster (Fruit fly) PR
P23396 RPS3 40S ribosomal protein S3 Homo sapiens (Human) PR
P62908 Rps3 40S ribosomal protein S3 Mus musculus (Mouse) PR
Q9FJA6 RPS3C 40S ribosomal protein S3-3 Arabidopsis thaliana (Mouse-ear cress) PR
Q9M339 RPS3B 40S ribosomal protein S3-2 Arabidopsis thaliana (Mouse-ear cress) PR
Q9SIP7 RPS3A 40S ribosomal protein S3-1 Arabidopsis thaliana (Mouse-ear cress) PR
10 20 30 40 50 60
MAANQNVTKK KKAVIGGIFK AELNNFLMKE LAEDGYSGVE VRSTPARAEV IIMATRTQNV
70 80 90 100 110 120
LGERGRRIKE LTSVVQKRFG FEEGSVELYA EKVSNRGLCA VAQCESLRYK LVGGLAVRRA
130 140 150 160 170 180
CYGVLRFIME SGAQGVEVIV SGKLRGQRAK AMKFVDGLMI HSGHPVNDYI QQAVRHVQLR
190 200 210 220 230 240
QGVIGIKVKI MLPYDPRGQN GPRNALPDHV QIVEPQEEVL PKEPHSQHKE EKKDVQVPAA
QPVAPVQ