Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

Autoinhibited structure

Activated structure

1 structures for Q9FJA6

Entry ID Method Resolution Chain Position Source
AF-Q9FJA6-F1 Predicted AlphaFoldDB

9 variants for Q9FJA6

Variant ID(s) Position Change Description Diseaes Association Provenance
ENSVATH14514328 36 G>S No 1000Genomes
tmp_5_13711975_T_A 44 M>L No 1000Genomes
ENSVATH11931437 169 D>N No 1000Genomes
tmp_5_13710675_C_G 173 R>T No 1000Genomes
tmp_5_13710467_G_C 212 T>R No 1000Genomes
tmp_5_13710447_A_G 219 Y>H No 1000Genomes
ENSVATH11931403 224 Q>L No 1000Genomes
tmp_5_13710420_G_C 228 Q>E No 1000Genomes
tmp_5_13710398_G_A 235 A>V No 1000Genomes

No associated diseases with Q9FJA6

2 regional properties for Q9FJA6

Type Name Position InterPro Accession
domain Ribosomal protein S3, C-terminal 106 - 188 IPR001351
domain K Homology domain, type 2 20 - 93 IPR004044

Functions

Description
EC Number
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

6 GO annotations of cellular component

Name Definition
cytosolic ribosome A ribosome located in the cytosol.
cytosolic small ribosomal subunit The small subunit of a ribosome located in the cytosol.
nucleolus A small, dense body one or more of which are present in the nucleus of eukaryotic cells. It is rich in RNA and protein, is not bounded by a limiting membrane, and is not seen during mitosis. Its prime function is the transcription of the nucleolar DNA into 45S ribosomal-precursor RNA, the processing of this RNA into 5.8S, 18S, and 28S components of ribosomal RNA, and the association of these components with 5S RNA and proteins synthesized outside the nucleolus. This association results in the formation of ribonucleoprotein precursors; these pass into the cytoplasm and mature into the 40S and 60S subunits of the ribosome.
nucleus A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
plasmodesma A fine cytoplasmic channel, found in all higher plants, that connects the cytoplasm of one cell to that of an adjacent cell.
plastid Any member of a family of organelles found in the cytoplasm of plants and some protists, which are membrane-bounded and contain DNA. Plant plastids develop from a common type, the proplastid.

2 GO annotations of molecular function

Name Definition
mRNA binding Binding to messenger RNA (mRNA), an intermediate molecule between DNA and protein. mRNA includes UTR and coding sequences, but does not contain introns.
structural constituent of ribosome The action of a molecule that contributes to the structural integrity of the ribosome.

1 GO annotations of biological process

Name Definition
translation The cellular metabolic process in which a protein is formed, using the sequence of a mature mRNA or circRNA molecule to specify the sequence of amino acids in a polypeptide chain. Translation is mediated by the ribosome, and begins with the formation of a ternary complex between aminoacylated initiator methionine tRNA, GTP, and initiation factor 2, which subsequently associates with the small subunit of the ribosome and an mRNA or circRNA. Translation ends with the release of a polypeptide chain from the ribosome.

7 homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
P05750 RPS3 40S ribosomal protein S3 Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) PR
Q06559 RpS3 40S ribosomal protein S3 Drosophila melanogaster (Fruit fly) PR
P23396 RPS3 40S ribosomal protein S3 Homo sapiens (Human) PR
P62908 Rps3 40S ribosomal protein S3 Mus musculus (Mouse) PR
P48152 rps-3 40S ribosomal protein S3 Caenorhabditis elegans PR
Q9M339 RPS3B 40S ribosomal protein S3-2 Arabidopsis thaliana (Mouse-ear cress) PR
Q9SIP7 RPS3A 40S ribosomal protein S3-1 Arabidopsis thaliana (Mouse-ear cress) PR
10 20 30 40 50 60
MATQISKKRK FVADGVFYAE LNEVLTRELA EDGYSGVEVR VTPMRTEIII RATRTQNVLG
70 80 90 100 110 120
EKGRRIRELT SLVQKRFKFP QDSVELYAEK VANRGLCAIA QAESLRYKLL GGLAVRRACY
130 140 150 160 170 180
GVLRFVMESG AKGCEVIVSG KLRAARAKSM KFKDGYMVSS GQPTKEYIDA AVRHVLLRQG
190 200 210 220 230 240
VLGLKVKIML DWDPKGKQGP MTPLPDVVII HTPKEDDVYI APAQVVTQAA FVPEAPLTTT
DYPAMPVA