AiPD: Autoinhibited Protein Database

Gene name	ORP1D (At1g13170, F3F19.19)
Protein name	Oxysterol-binding protein-related protein 1D
Names	OSBP-related protein 1D
Species	Arabidopsis thaliana (Mouse-ear cress)
KEGG Pathway	ath:AT1G13170
EC number
Protein Class

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

303-453 (Predicted disordered autoinhibitory region) PR

303-453 (Predicted disordered autoinhibitory region)

cis-regPred

No accessory elements

Entry ID	Method	Resolution	Chain	Position	Source
AF-Q9SAF0-F1	Predicted				AlphaFoldDB

Variant ID(s)	Position	Change	Diseaes Association	Provenance
tmp_1_4492218_C_T	21	A>T	No	1000Genomes
tmp_1_4492200_G_A	27	H>Y	No	1000Genomes
ENSVATH04568805	36	S>I	No	1000Genomes
tmp_1_4492167_G_A	38	H>Y	No	1000Genomes
ENSVATH04568804	69	L>H	No	1000Genomes
ENSVATH04568801	127	H>R	No	1000Genomes
ENSVATH01045223	137	S>C	No	1000Genomes
ENSVATH01045222	139	E>D	No	1000Genomes
tmp_1_4491791_C_T	163	R>Q	No	1000Genomes
tmp_1_4491531_G_C	219	A>G	No	1000Genomes
ENSVATH04568800	225	Q>E	No	1000Genomes
tmp_1_4491511_C_T	226	V>M	No	1000Genomes
tmp_1_4491507_G_A	227	A>V	No	1000Genomes
ENSVATH04568799	230	L>H	No	1000Genomes
ENSVATH00021193	238	D>N	No	1000Genomes
tmp_1_4491436_T_C	251	K>E	No	1000Genomes
tmp_1_4491406_C_T	261	V>I	No	1000Genomes
tmp_1_4490635_G_A	383	R>C	No	1000Genomes
ENSVATH04568789	389	G>A	No	1000Genomes
ENSVATH01045212	390	N>T	No	1000Genomes
tmp_1_4490605_T_G	393	I>L	No	1000Genomes
ENSVATH00021190	406	I>V	No	1000Genomes
tmp_1_4490518_A_T	422	L>I	No	1000Genomes
ENSVATH11121626	429	E>D	No	1000Genomes
ENSVATH00021189	480	E>D	No	1000Genomes
tmp_1_4490013_G_A	531	R>C	No	1000Genomes
tmp_1_4490003_G_C	534	S>C	No	1000Genomes
tmp_1_4489699_C_T	584	D>N	No	1000Genomes
tmp_1_4489672_C_T	593	V>I	No	1000Genomes
tmp_1_4489559_C_A	630	Q>H	No	1000Genomes
ENSVATH11121531	634	D>E	No	1000Genomes
ENSVATH04568781	664	M>I	No	1000Genomes
ENSVATH01045211	695	T>S	No	1000Genomes
tmp_1_4489137_C_T	747	R>K	No	1000Genomes
ENSVATH13889252	754	Q>L	No	1000Genomes
tmp_1_4488967_T_G	770	K>N	No	1000Genomes
tmp_1_4488896_A_G	794	I>T	No	1000Genomes
ENSVATH11121529	802	Q>L	No	1000Genomes

Type	Name	Position	InterPro Accession
domain	Pleckstrin homology domain	92 - 231	IPR001849

		Description
EC Number
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category	No pathway information available

Name	Definition
cytosol	The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
intracellular membrane-bounded organelle	Organized structure of distinctive morphology and function, bounded by a single or double lipid bilayer membrane and occurring within the cell. Includes the nucleus, mitochondria, plastids, vacuoles, and vesicles. Excludes the plasma membrane.
membrane	A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it.

Name	Definition
sterol binding	Binding to a sterol, a steroid containing a hydroxy group in the 3 position, closely related to cholestan-3-ol.
sterol transporter activity	Enables the directed movement of sterols into, out of or within a cell, or between cells. Sterol are steroids with one or more hydroxyl groups and a hydrocarbon side-chain in the molecule.

Name	Definition
No GO annotations for biological process

UniProt AC	Gene Name	Protein Name	Species	Evidence Code
P22059	OSBP	Oxysterol-binding protein 1	Homo sapiens (Human)	PR
Q969R2	OSBP2	Oxysterol-binding protein 2	Homo sapiens (Human)	PR
Q3B7Z2	Osbp	Oxysterol-binding protein 1	Mus musculus (Mouse)	PR
Q5QNQ6	Osbp2	Oxysterol-binding protein 2	Mus musculus (Mouse)	PR
Q8S8P9	ORP1B	Oxysterol-binding protein-related protein 1B	Arabidopsis thaliana (Mouse-ear cress)	PR
Q8L751	ORP1C	Oxysterol-binding protein-related protein 1C	Arabidopsis thaliana (Mouse-ear cress)	PR