Q8S8P9
Gene name |
ORP1B (At2g31030, F7F1.24) |
Protein name |
Oxysterol-binding protein-related protein 1B |
Names |
OSBP-related protein 1B |
Species |
Arabidopsis thaliana (Mouse-ear cress) |
KEGG Pathway |
ath:AT2G31030 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q8S8P9
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q8S8P9-F1 | Predicted | AlphaFoldDB |
58 variants for Q8S8P9
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| ENSVATH05635507 | 6 | I>V | No | 1000Genomes | |
| ENSVATH05635508 | 20 | A>V | No | 1000Genomes | |
| tmp_2_13206064_G_C | 21 | V>L | No | 1000Genomes | |
| tmp_2_13206106_A_G | 35 | N>D | No | 1000Genomes | |
| tmp_2_13206116_C_T | 38 | T>M | No | 1000Genomes | |
| ENSVATH13488589 | 53 | E>A | No | 1000Genomes | |
| tmp_2_13206185_T_A | 61 | L>H | No | 1000Genomes | |
| ENSVATH14574328 | 68 | R>K | No | 1000Genomes | |
| tmp_2_13206212_G_A | 70 | S>N | No | 1000Genomes | |
| ENSVATH05635510 | 102 | I>L | No | 1000Genomes | |
| tmp_2_13206410_C_A | 107 | P>T | No | 1000Genomes | |
| tmp_2_13206430_T_G | 113 | N>K | No | 1000Genomes | |
| tmp_2_13206483_T_C | 131 | I>T | No | 1000Genomes | |
| tmp_2_13206532_C_A | 147 | Y>* | No | 1000Genomes | |
| tmp_2_13206621_G_A | 177 | R>K | No | 1000Genomes | |
| ENSVATH01931917 | 178 | G>D | No | 1000Genomes | |
| ENSVATH05635514 | 186 | N>I | No | 1000Genomes | |
| tmp_2_13206735_G_A | 187 | V>I | No | 1000Genomes | |
| tmp_2_13206748_C_T | 191 | A>V | No | 1000Genomes | |
| ENSVATH05635515 | 199 | K>I | No | 1000Genomes | |
| tmp_2_13206784_G_C | 203 | C>S | No | 1000Genomes | |
| ENSVATH13488612 | 209 | M>V | No | 1000Genomes | |
| tmp_2_13206813_A_G | 213 | T>A | No | 1000Genomes | |
| ENSVATH13488613 | 214 | Y>H | No | 1000Genomes | |
| ENSVATH13488614 | 219 | P>A | No | 1000Genomes | |
| ENSVATH13488625 | 224 | R>* | No | 1000Genomes | |
| ENSVATH01931918 | 224 | R>Q | No | 1000Genomes | |
| ENSVATH14574329 | 225 | F>V | No | 1000Genomes | |
| tmp_2_13206976_G_T | 237 | V>L | No | 1000Genomes | |
| ENSVATH05635518 | 240 | H>Y | No | 1000Genomes | |
| ENSVATH05635519 | 244 | T>N | No | 1000Genomes | |
| tmp_2_13207087_C_G | 274 | Q>E | No | 1000Genomes | |
| ENSVATH13488628 | 281 | V>L | No | 1000Genomes | |
| ENSVATH01931922 | 310 | G>A | No | 1000Genomes | |
| tmp_2_13207292_G_C | 316 | C>S | No | 1000Genomes | |
| tmp_2_13207349_G_C | 335 | G>A | No | 1000Genomes | |
| ENSVATH13488630 | 355 | S>N | No | 1000Genomes | |
| ENSVATH05635522 | 358 | Y>N | No | 1000Genomes | |
| ENSVATH05635523 | 364 | G>R | No | 1000Genomes | |
| tmp_2_13207457_T_A | 371 | L>H | No | 1000Genomes | |
| tmp_2_13207462_T_G | 373 | W>G | No | 1000Genomes | |
| tmp_2_13207480_C_G | 379 | L>V | No | 1000Genomes | |
| ENSVATH14574330 | 391 | G>R | No | 1000Genomes | |
| ENSVATH00255435 | 398 | T>M | No | 1000Genomes | |
| tmp_2_13207557_G_A | 404 | M>I | No | 1000Genomes | |
| tmp_2_13207562_C_T | 406 | P>L | No | 1000Genomes | |
| tmp_2_13207564_C_T | 407 | P>S | No | 1000Genomes | |
| tmp_2_13207622_T_G | 426 | M>R | No | 1000Genomes | |
| tmp_2_13207651_C_G | 436 | Q>E | No | 1000Genomes | |
| ENSVATH14574331 | 437 | R>M | No | 1000Genomes | |
| tmp_2_13207671_A_C | 442 | R>S | No | 1000Genomes | |
| ENSVATH00255436 | 452 | T>K | No | 1000Genomes | |
| ENSVATH01931923 | 455 | S>R | No | 1000Genomes | |
| ENSVATH01931924 | 456 | K>E | No | 1000Genomes | |
| ENSVATH13488631 | 457 | E>V | No | 1000Genomes | |
| tmp_2_13207744_G_A | 467 | G>R | No | 1000Genomes | |
| tmp_2_13207784_A_T | 480 | D>V | No | 1000Genomes | |
| tmp_2_13207801_G_A | 486 | G>S | No | 1000Genomes |
No associated diseases with Q8S8P9
No regional properties for Q8S8P9
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| No domain, repeats, and functional sites for Q8S8P9 | |||
3 GO annotations of cellular component
| Name | Definition |
|---|---|
| cytosol | The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes. |
| intracellular membrane-bounded organelle | Organized structure of distinctive morphology and function, bounded by a single or double lipid bilayer membrane and occurring within the cell. Includes the nucleus, mitochondria, plastids, vacuoles, and vesicles. Excludes the plasma membrane. |
| membrane | A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it. |
2 GO annotations of molecular function
| Name | Definition |
|---|---|
| sterol binding | Binding to a sterol, a steroid containing a hydroxy group in the 3 position, closely related to cholestan-3-ol. |
| sterol transporter activity | Enables the directed movement of sterols into, out of or within a cell, or between cells. Sterol are steroids with one or more hydroxyl groups and a hydrocarbon side-chain in the molecule. |
No GO annotations of biological process
| Name | Definition |
|---|---|
| No GO annotations for biological process |
6 homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| P22059 | OSBP | Oxysterol-binding protein 1 | Homo sapiens (Human) | PR |
| Q969R2 | OSBP2 | Oxysterol-binding protein 2 | Homo sapiens (Human) | PR |
| Q5QNQ6 | Osbp2 | Oxysterol-binding protein 2 | Mus musculus (Mouse) | PR |
| Q3B7Z2 | Osbp | Oxysterol-binding protein 1 | Mus musculus (Mouse) | PR |
| Q9SAF0 | ORP1D | Oxysterol-binding protein-related protein 1D | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q8L751 | ORP1C | Oxysterol-binding protein-related protein 1C | Arabidopsis thaliana (Mouse-ear cress) | PR |
| 10 | 20 | 30 | 40 | 50 | 60 |
| MEARVISCTT | FGDNKVVKIA | VLNHQAITKY | KAGENETTVV | VSDDTCPEKD | VKEIKKFCEK |
| 70 | 80 | 90 | 100 | 110 | 120 |
| LGYVYEGRLS | EEYTQTNTGP | DDDWITNGFE | SDDDVDPSIK | TIGFNYPHVN | RRNKLPDPVE |
| 130 | 140 | 150 | 160 | 170 | 180 |
| KEKSVSLWSM | IKDNIGKDLT | KVCLPVYFNE | PLSSLQKCFE | DLEYSYLLDQ | ASEWGKRGNN |
| 190 | 200 | 210 | 220 | 230 | 240 |
| LMRILNVAAF | AVSGYASTKG | RICKPFNPML | GETYEADYPD | KGLRFFSEKV | SHHPMIVACH |
| 250 | 260 | 270 | 280 | 290 | 300 |
| CDGTGWKFWG | DSNLKSKFWG | RSIQLDPIGL | LTLQFDDGEI | VQWSKVTTSI | YNLILGKLYC |
| 310 | 320 | 330 | 340 | 350 | 360 |
| DHYGTMLIEG | NGEYSCKLKF | KKQSMMDRNP | HQVQGIVEDK | NGKTVAKLFG | KWDESMYYVM |
| 370 | 380 | 390 | 400 | 410 | 420 |
| VNQGKESESH | LLWKRNKPLE | NPTKYNLTRF | GITLNELTPD | LKEMLPPTDS | RLRPDQRYLE |
| 430 | 440 | 450 | 460 | 470 | 480 |
| KGEFEMGNRE | KLRLEQRQRQ | AREKQERGWK | PTWFSKEKGS | ETYRYIGGYW | EARDSGRWDD |
| CPDIFGQVH |