AiPD: Autoinhibited Protein Database

Q9P0V9

Gene name	SEPTIN10
Protein name	Septin-10
Names
Species	Homo sapiens (Human)
KEGG Pathway	hsa:151011
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-66 (Predicted disordered autoinhibitory region) PR

Target domain
Relief mechanism
Assay	cis-regPred

AID

1-66 (Predicted disordered autoinhibitory region)

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Yeon JH et al. (2016) "Systems-wide Identification of cis-Regulatory Elements in Proteins", Cell Systems, 2, 89-100

Autoinhibited structure

Activated structure

1 structures for Q9P0V9

Entry ID	Method	Resolution	Chain	Position	Source
AF-Q9P0V9-F1	Predicted				AlphaFoldDB

479 variants for Q9P0V9

Variant ID(s)	Position	Change	Description	Diseaes Association	Provenance
CA1826464 rs372772922	2	A>V		No	ClinGen ESP ExAC TOPMed gnomAD
CA348076421 rs1303705353	4	S>A		No	ClinGen gnomAD
CA348076398 rs1426538614	6	V>M		No	ClinGen TOPMed gnomAD
rs1317852625 CA348076378	7	A>E		No	ClinGen TOPMed gnomAD
CA348076373 rs1317852625	7	A>V		No	ClinGen TOPMed gnomAD
CA1826463 rs747118357	8	R>W		No	ClinGen ExAC gnomAD
rs1406013329 CA348076347	9	H>Q		No	ClinGen TOPMed
rs1397924718 CA348076335	10	L>P		No	ClinGen TOPMed
rs368644892 CA53520148	10	L>V		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
rs1272149678 CA348074416	13	Q>E		No	ClinGen TOPMed gnomAD
rs763799724 CA1826452	13	Q>R		No	ClinGen ExAC TOPMed gnomAD
CA348074395 rs1284970253	14	S>F		No	ClinGen gnomAD
rs1225447949 CA348074402	14	S>P		No	ClinGen gnomAD
TCGA novel	14	S>T	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs1326062424 CA348074389	15	H>Y		No	ClinGen gnomAD
CA348074372 rs1472917051	16	M>I		No	ClinGen TOPMed
CA1826450 rs368405950	16	M>V		No	ClinGen ESP ExAC TOPMed gnomAD
rs376547232 CA1826448	18	T>K		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
CA1826449 rs376547232	18	T>M		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
CA53509820 rs976750536	21	T>A		No	ClinGen Ensembl
rs1480568851 CA348074297	23	M>T		No	ClinGen gnomAD
rs766278428 CA1826446	23	M>V		No	ClinGen ExAC TOPMed gnomAD
rs760780109 CA1826445	24	S>Y		No	ClinGen ExAC gnomAD
rs772237958 CA1826443	28	S>*		No	ClinGen ExAC gnomAD
rs1250404291 CA348074224	29	D>G		No	ClinGen gnomAD
CA1826442 rs373916982	31	E>K		No	ClinGen ESP ExAC gnomAD
rs774633021 CA1826441	31	E>V		No	ClinGen ExAC gnomAD
CA348074190 rs1293046585	32	Q>E		No	ClinGen TOPMed
TCGA novel	32	Q>H	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA348074184 rs1203202322	32	Q>P		No	ClinGen TOPMed gnomAD
CA348074185 rs1203202322	32	Q>R		No	ClinGen TOPMed gnomAD
rs1324518840 CA348074167	33	I>M		No	ClinGen gnomAD
CA1826424 rs766151908	35	R>K		No	ClinGen ExAC TOPMed gnomAD
CA1826423 rs754782614	35	R>S		No	ClinGen ExAC gnomAD
CA53505919 rs903912507	36	E>K		No	ClinGen TOPMed
CA1826419 rs373616560	39	R>C	Variant assessed as Somatic; impact. [NCI-TCGA]	No	ClinGen ESP ExAC NCI-TCGA TOPMed gnomAD
rs373616560 CA1826420	39	R>G		No	ClinGen ESP ExAC TOPMed gnomAD
CA1826418 rs371041273	39	R>H		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
CA348073293 rs371041273	39	R>P		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
CA1826416 rs761951489	40	S>L		No	ClinGen ExAC TOPMed gnomAD
rs768798518 CA1826414	41	L>F		No	ClinGen ExAC TOPMed gnomAD
CA1826413 rs760434343	43	M>V		No	ClinGen ExAC TOPMed gnomAD
CA348073242 rs1239293944	44	S>C		No	ClinGen TOPMed gnomAD
CA1826412 rs199941021	45	G>S		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
CA348073205 rs1218480171	48	G>D		No	ClinGen TOPMed gnomAD
CA53505837 rs984412691	49	F>L		No	ClinGen TOPMed gnomAD
rs1475783349 CA348072547	50	E>K		No	ClinGen Ensembl
CA348072487 rs1223471672	52	L>V		No	ClinGen TOPMed
rs373723750 CA1826410	53	P>L		No	ClinGen ESP ExAC TOPMed gnomAD
rs1310260309 CA348072452	53	P>S		No	ClinGen TOPMed
rs944934587 CA53505820	54	D>G		No	ClinGen TOPMed
CA1826409 rs761863838	54	D>N		No	ClinGen ExAC gnomAD
CA348072393 rs575725787	55	Q>*		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
CA1826408 rs575725787	55	Q>E		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
rs771693820 CA1826407	59	R>G		No	ClinGen ExAC gnomAD
TCGA novel	59	R>K	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs1226130137 CA348072278	60	S>A		No	ClinGen gnomAD
TCGA novel	61	I>F	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA53505799 rs150267546	61	I>V		No	ClinGen 1000Genomes
COSM3425099 rs1029140539 CA53505797 COSM3425098	62	Q>R	large_intestine Variant assessed as Somatic; impact. [Cosmic, NCI-TCGA]	No	ClinGen cosmic curated Ensembl NCI-TCGA
CA1826406 rs747707215	63	Q>R		No	ClinGen ExAC TOPMed gnomAD
CA1826404 rs754620140	64	G>A		No	ClinGen ExAC TOPMed gnomAD
rs754620140 CA348072193	64	G>D		No	ClinGen ExAC TOPMed gnomAD
rs1402210262 CA348072202	64	G>S		No	ClinGen TOPMed gnomAD
CA348072150 rs1425863794	66	C>R		No	ClinGen gnomAD
rs1441081696 CA348072142	66	C>S		No	ClinGen TOPMed
rs755982386 CA1826401	67	F>C		No	ClinGen ExAC TOPMed gnomAD
rs755982386 CA1826402	67	F>S		No	ClinGen ExAC TOPMed gnomAD
rs1166230069 CA348072079	68	N>H		No	ClinGen gnomAD
CA1826400 rs767504524	68	N>S		No	ClinGen ExAC TOPMed gnomAD
CA1826399 rs767504524	68	N>T		No	ClinGen ExAC TOPMed gnomAD
CA1826398 rs761861677	70	L>F		No	ClinGen ExAC gnomAD
TCGA novel	70	L>V	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA1826396 rs764324375	71	C>G		No	ClinGen ExAC TOPMed gnomAD
CA348071982 rs369040281	71	C>S		No	ClinGen ESP ExAC TOPMed gnomAD
rs764324375 CA53505758	71	C>S		No	ClinGen ExAC TOPMed gnomAD
CA1826395 rs369040281	71	C>Y		No	ClinGen ESP ExAC TOPMed gnomAD
CA348071961 rs1223057955	72	V>M		No	ClinGen gnomAD
CA348071809 rs1420379192	73	G>E		No	ClinGen TOPMed
CA1826374 TCGA novel rs758570482	74	E>K	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA ClinGen ExAC gnomAD
CA348071741 rs1243981571	76	G>E		No	ClinGen Ensembl
rs1177478203 CA348071733	77	I>T		No	ClinGen gnomAD
rs370129746 CA1826373	77	I>V		No	ClinGen ESP ExAC gnomAD
CA348071716 rs1415907303	78	G>V	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen NCI-TCGA gnomAD
rs765603907 CA1826372	79	K>R		No	ClinGen ExAC gnomAD
CA53505513 rs777555335	80	S>L		No	ClinGen Ensembl
CA1826369 rs777169237	81	T>A		No	ClinGen ExAC TOPMed gnomAD
CA348071665 rs1340811068	81	T>I		No	ClinGen TOPMed
rs1460526673 CA348071643	82	L>R		No	ClinGen gnomAD
CA1826368 rs779823796	82	L>V		No	ClinGen ExAC TOPMed gnomAD
rs1211841532 CA348071634	83	I>S		No	ClinGen TOPMed gnomAD
rs773844806 CA1826366	85	T>A		No	ClinGen ExAC TOPMed
rs1314242639 CA348071592	85	T>I		No	ClinGen TOPMed gnomAD
rs1355045330 CA348071577	86	L>S		No	ClinGen gnomAD
rs1036516905 CA53505490	88	N>S		No	ClinGen TOPMed
rs375814807 CA1826364	89	T>I		No	ClinGen ESP ExAC TOPMed gnomAD
rs774985954 CA1826363	90	N>D		No	ClinGen ExAC gnomAD
rs1382150587 CA348071470	90	N>K		No	ClinGen gnomAD
CA348071439 rs1303600336	92	E>K		No	ClinGen gnomAD
CA1826359 rs531592924	94	Y>C		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
CA1826360 rs531592924	94	Y>F		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
rs769479944 CA1826362	94	Y>N		No	ClinGen ExAC
CA348071399 rs531592924	94	Y>S		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
CA348071355 rs1180014322	97	S>L		No	ClinGen TOPMed
CA1826358 rs757115897	98	H>R		No	ClinGen ExAC TOPMed gnomAD
CA348071338 rs1382076137	99	F>Y		No	ClinGen gnomAD
rs777822989 CA1826356	101	P>T		No	ClinGen ExAC gnomAD
CA348071287 rs79975047	102	N>D		No	ClinGen ExAC gnomAD
CA1826354 rs77983749	102	N>I		No	ClinGen ExAC gnomAD
CA1826355 rs79975047	102	N>Y		No	ClinGen ExAC gnomAD
CA53505425 rs887921205	104	K>R		No	ClinGen TOPMed
CA348071230 rs1484680324	105	L>P		No	ClinGen gnomAD
CA348071201 rs1464516590	107	A>D		No	ClinGen TOPMed
CA348071188 rs1558827350	108	Q>*		No	ClinGen Ensembl
CA1826351 rs755274060	109	T>A		No	ClinGen ExAC TOPMed gnomAD
CA348071157 rs1402715333	109	T>I		No	ClinGen TOPMed
rs1244457782 CA348071139	110	Y>C		No	ClinGen gnomAD
rs766855175 CA1826349	111	E>K		No	ClinGen ExAC gnomAD
CA1826348 rs761173204	112	L>F		No	ClinGen ExAC gnomAD
CA348071041 rs1558827118	115	S>G		No	ClinGen Ensembl
CA348071025 rs1288567366	116	N>D		No	ClinGen gnomAD
CA1826347 rs750885338	116	N>S		No	ClinGen ExAC gnomAD
rs1362256002 CA348070998	117	V>G		No	ClinGen gnomAD
rs192284223 CA1826346	119	L>F		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
rs762341040 CA1826345	121	L>W		No	ClinGen ExAC TOPMed gnomAD
CA53505396 rs372542138	122	T>N		No	ClinGen ESP TOPMed
rs775001002 CA1826344	123	I>V		No	ClinGen ExAC gnomAD
rs1418321675 CA348070880	124	V>M		No	ClinGen gnomAD
CA348070862 rs1573680647	125	N>H		No	ClinGen Ensembl
CA1826343 rs769375920	125	N>S		No	ClinGen ExAC gnomAD
CA348070793 rs1321651155	128	G>A		No	ClinGen TOPMed gnomAD
rs944490082 CA53505374	129	F>V		No	ClinGen TOPMed gnomAD
rs759190118 CA1826342	130	G>D		No	ClinGen ExAC gnomAD
CA53505372 rs940884936	131	D>E		No	ClinGen TOPMed
rs1224375768 CA348070707	132	Q>R		No	ClinGen gnomAD
CA1826341 rs776328974	133	I>V		No	ClinGen ExAC gnomAD
rs1490329152 CA348070610	135	K>T		No	ClinGen TOPMed gnomAD
rs1352810141 CA348070533	138	S>C		No	ClinGen gnomAD
rs756144716 CA53505364	138	S>N		No	ClinGen Ensembl
rs1331418944 CA348068259	140	Q>*		No	ClinGen TOPMed gnomAD
rs779061094 CA1826317	141	P>S		No	ClinGen ExAC gnomAD
rs749431866 CA1826315	142	I>V		No	ClinGen ExAC TOPMed gnomAD
CA1826314 rs780395467	145	Y>C		No	ClinGen ExAC TOPMed gnomAD
rs1469584939 CA348068160	146	I>T		No	ClinGen TOPMed
CA1826313 rs756393819	146	I>V		No	ClinGen ExAC TOPMed gnomAD
rs1178798190 CA535593928	147	D>*		No	ClinGen gnomAD
rs1417841945 CA348068142	147	D>G		No	ClinGen TOPMed gnomAD
rs768945992 CA1826312	147	D>V		No	ClinGen ExAC
rs1439480964 CA348068134	148	A>P		No	ClinGen gnomAD
rs367885411 CA1826311	148	A>V		No	ClinGen ESP ExAC TOPMed gnomAD
CA1826310 rs781621559	149	Q>*		No	ClinGen ExAC gnomAD
CA1826309 rs757625865	149	Q>P		No	ClinGen ExAC TOPMed gnomAD
CA348068098 rs1241470246	150	F>S	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen NCI-TCGA gnomAD
rs567145471 CA53499039	152	A>V		No	ClinGen Ensembl
rs764633806 CA348068033	153	Y>*		No	ClinGen ExAC gnomAD
rs752044871 COSM569452 COSM1141766 CA1826308	153	Y>C	lung Variant assessed as Somatic; 0.0 impact. [Cosmic, NCI-TCGA]	No	ClinGen cosmic curated ExAC NCI-TCGA TOPMed gnomAD
CA1826306 rs56280142	156	E>K		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
rs1353213251 CA348067974	156	E>V		No	ClinGen TOPMed
rs1236685418 CA348067966	157	E>*		No	ClinGen gnomAD
rs1236685418 CA348067967	157	E>Q		No	ClinGen gnomAD
rs202055528 CA1826305	158	L>M		No	ClinGen ExAC TOPMed gnomAD
CA348067951 rs1237094945	158	L>R		No	ClinGen gnomAD
CA348067945 rs1573591112	159	K>Q		No	ClinGen Ensembl
CA348067924 rs1351793554	160	I>M		No	ClinGen TOPMed
rs765897906 CA1826304	160	I>S		No	ClinGen ExAC gnomAD
CA1826303 rs760390400	162	R>C		No	ClinGen ExAC TOPMed gnomAD
rs371218240 CA1826302	162	R>H	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen ESP ExAC NCI-TCGA TOPMed gnomAD
rs368911337 CA1826301	164	L>V		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
rs199690667 CA1826300	166	T>I		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
rs1573590808 CA348067848	166	T>P		No	ClinGen Ensembl
rs774411951 CA1826299	167	Y>C		No	ClinGen ExAC TOPMed gnomAD
CA1826298 rs768758223	168	H>Y		No	ClinGen ExAC gnomAD
CA1826297 rs371324848	169	D>A		No	ClinGen ESP ExAC TOPMed gnomAD
CA348067759 rs1205783685	170	S>F		No	ClinGen TOPMed
rs376756696 CA1826296	171	R>C	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen ESP ExAC NCI-TCGA TOPMed gnomAD
rs780288687 COSM1590462 CA1826295 COSM1005333	171	R>H	Variant assessed as Somatic; 0.0 impact. central_nervous_system endometrium [NCI-TCGA, Cosmic]	No	ClinGen cosmic curated ExAC NCI-TCGA TOPMed gnomAD
CA53499010 rs925039865	172	I>M		No	ClinGen TOPMed
CA1826294 rs746096708	173	H>R		No	ClinGen ExAC TOPMed gnomAD
CA1826292 rs757616182	174	V>L		No	ClinGen ExAC TOPMed gnomAD
CA1826293 rs757616182	174	V>M		No	ClinGen ExAC TOPMed gnomAD
CA53499001 rs936407812	175	C>R		No	ClinGen Ensembl
rs1258610046 CA348067674	175	C>S		No	ClinGen gnomAD
rs375470343 CA1826291	176	L>V		No	ClinGen ESP ExAC TOPMed gnomAD
rs200382879 CA1826289	178	F>L		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
rs377499673 CA1826288	178	F>S		No	ClinGen ESP ExAC TOPMed gnomAD
CA348067598 rs1313722630	179	I>T		No	ClinGen gnomAD
CA1826287 rs185846561	179	I>V		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
rs368933601 CA1826286	180	S>L		No	ClinGen ESP ExAC TOPMed gnomAD
CA1826285 rs377574367	181	P>L		No	ClinGen ESP ExAC TOPMed gnomAD
CA348067557 rs1380835284	182	T>A		No	ClinGen gnomAD
COSM1005332 rs761673341 COSM1153473 CA1826283	183	G>D	Variant assessed as Somatic; 0.0 impact. large_intestine endometrium [NCI-TCGA, Cosmic]	No	ClinGen cosmic curated ExAC NCI-TCGA TOPMed gnomAD
rs1299268542 CA348067501	184	H>R		No	ClinGen gnomAD
rs1422074833 CA348067488	185	S>A		No	ClinGen gnomAD
CA1826282 rs774321778	185	S>C		No	ClinGen ExAC gnomAD
CA348067493 rs1422074833	185	S>T		No	ClinGen gnomAD
COSM3797835 CA348067475 rs1558788905 COSM3797834	186	L>V	Variant assessed as Somatic; 0.0 impact. urinary_tract [NCI-TCGA, Cosmic]	No	ClinGen cosmic curated Ensembl NCI-TCGA
rs1473196062 CA348067456	187	K>E		No	ClinGen TOPMed gnomAD
CA53498945 rs775354135	189	L>F		No	ClinGen ExAC TOPMed gnomAD
rs3829701 VAR_051936 CA1826276	189	L>P		No	ClinGen UniProt 1000Genomes ExAC TOPMed dbSNP gnomAD
CA1826277 rs775354135	189	L>V		No	ClinGen ExAC TOPMed gnomAD
CA1826272 rs540248161	190	D>G		No	ClinGen ExAC TOPMed gnomAD
rs776879717 CA1826275	190	D>H		No	ClinGen ExAC gnomAD
rs776879717 CA1826274	190	D>N		No	ClinGen ExAC gnomAD
CA1826273 rs540248161	190	D>V		No	ClinGen ExAC TOPMed gnomAD
CA348067375 rs1342863949	191	L>F		No	ClinGen gnomAD
rs778123198 CA1826270	194	M>V		No	ClinGen ExAC TOPMed gnomAD
CA1826269 rs772502792	195	K>N		No	ClinGen ExAC gnomAD
CA1826268 rs369971346	196	N>D		No	ClinGen ESP ExAC gnomAD
TCGA novel	197	L>I	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA348067206 rs1452330795	199	S>G		No	ClinGen TOPMed
CA348067160 rs749945195	200	K>M		No	ClinGen ExAC TOPMed gnomAD
CA1826266 rs749945195	200	K>R		No	ClinGen ExAC TOPMed gnomAD
rs749945195 CA1826265	200	K>T		No	ClinGen ExAC TOPMed gnomAD
rs1220007053 CA348072608	201	V>I		No	ClinGen gnomAD
rs772413149 CA1826246	203	I>T		No	ClinGen ExAC gnomAD
CA348072541 rs1558765153	204	I>M		No	ClinGen Ensembl
rs748510504 CA1826245	206	V>A		No	ClinGen ExAC gnomAD
rs780674616 CA1826244	207	I>M		No	ClinGen ExAC TOPMed gnomAD
CA53512493 rs896311797	209	K>E		No	ClinGen gnomAD
CA348072465 rs896311797	209	K>Q		No	ClinGen gnomAD
CA1826243 rs769078613	210	A>T		No	ClinGen ExAC gnomAD
CA348072409 rs1173027896	211	D>G		No	ClinGen gnomAD
CA1826242 rs756418889	212	T>M		No	ClinGen ExAC TOPMed gnomAD
CA1826240 rs756892026	213	V>A		No	ClinGen ExAC
rs751241879 CA1826239	214	S>C		No	ClinGen ExAC TOPMed gnomAD
rs751241879 CA348072349	214	S>F		No	ClinGen ExAC TOPMed gnomAD
CA348072336 rs1457860720	215	K>E		No	ClinGen gnomAD
rs758232657 CA1826237	217	E>K		No	ClinGen ExAC gnomAD
rs758232657 CA348072298	217	E>Q		No	ClinGen ExAC gnomAD
CA1826236 rs368742282	218	L>S		No	ClinGen ESP ExAC gnomAD
rs1365397495 CA348072244	219	Q>*		No	ClinGen TOPMed
CA348072239 rs1437746212	219	Q>R		No	ClinGen TOPMed
CA348072161 rs1558764606	222	K>E		No	ClinGen Ensembl
rs759404095 CA1826234	225	L>P		No	ClinGen ExAC TOPMed gnomAD
rs931268306 CA53512467	227	S>R		No	ClinGen Ensembl
CA348072012 rs758005172	230	V>I		No	ClinGen TOPMed gnomAD
rs758005172 CA53512460	230	V>L		No	ClinGen TOPMed gnomAD
rs753887223 COSM3708809 CA1826233 COSM3708810	232	N>S	liver [Cosmic]	No	ClinGen cosmic curated ExAC TOPMed gnomAD
rs1333531313 CA348071945	233	G>S		No	ClinGen gnomAD
rs760804797 CA1826231	234	V>I		No	ClinGen ExAC TOPMed gnomAD
CA53512442 rs752368017	235	Q>*	Variant assessed as Somatic; impact. [NCI-TCGA]	No	ClinGen Ensembl NCI-TCGA
rs1240294962 CA348071884	235	Q>H		No	ClinGen TOPMed
rs773401547 CA1826230	236	I>L		No	ClinGen ExAC gnomAD
rs375711131 CA1826229	236	I>R		No	ClinGen ESP ExAC gnomAD
CA1826228 rs764696551	237	Y>H		No	ClinGen ExAC gnomAD
rs202212880 CA1826225	238	Q>H		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
CA1826227 rs774603502	238	Q>K		No	ClinGen ExAC gnomAD
CA1826226 rs769153510	238	Q>P		No	ClinGen ExAC TOPMed gnomAD
CA53512411 rs769153510	238	Q>R		No	ClinGen ExAC TOPMed gnomAD
rs370927798 CA1826224	239	F>I		No	ClinGen ESP ExAC gnomAD
rs770538926 CA1826223	239	F>L		No	ClinGen ExAC gnomAD
CA1826222 rs572040032	241	T>A		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
CA1826221 rs777524713	241	T>M		No	ClinGen ExAC TOPMed gnomAD
CA348071786 rs572040032	241	T>S		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
CA348071748 rs1384956716	243	D>E		No	ClinGen TOPMed
CA348071760 rs1284451013	243	D>N		No	ClinGen gnomAD
CA53512378 rs925501417	244	D>G		No	ClinGen TOPMed gnomAD
rs896230011 CA53512370	245	T>N		No	ClinGen TOPMed
CA1826217 rs754870576	246	I>T		No	ClinGen ExAC TOPMed gnomAD
rs778575721 CA1826218	246	I>V		No	ClinGen ExAC TOPMed gnomAD
CA348071661 COSM1664096 COSM1664097 rs1378680315	247	A>G	kidney [Cosmic]	No	ClinGen cosmic curated gnomAD
rs1285054935 CA348071657	248	K>E		No	ClinGen gnomAD
rs1346718906 CA348071625	249	V>D		No	ClinGen gnomAD
CA1826216 rs377591042	250	N>S		No	ClinGen ESP ExAC TOPMed gnomAD
rs750537247 CA1826213	251	A>G		No	ClinGen ExAC gnomAD
CA1826214 rs201521865	251	A>T		No	ClinGen ExAC gnomAD
rs1243276268 CA348071554	253	M>V		No	ClinGen TOPMed
CA348071526 rs1362454240	254	N>S		No	ClinGen TOPMed gnomAD
TCGA novel	255	G>*	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA348070806 rs1407840783	256	Q>*		No	ClinGen gnomAD
rs1007214829 CA53511204	256	Q>R		No	ClinGen Ensembl
CA1826193 rs767502369	258	P>A		No	ClinGen ExAC TOPMed gnomAD
rs376369966 CA1826192	258	P>L		No	ClinGen ESP ExAC TOPMed gnomAD
rs199570779 CA1826190	259	F>L		No	ClinGen ESP ExAC TOPMed gnomAD
rs763185491 CA1826189	259	F>L		No	ClinGen ExAC TOPMed gnomAD
rs1223954228 CA348070650	260	A>V		No	ClinGen TOPMed gnomAD
CA1826186 rs536588521	262	V>A		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
rs536588521 CA348070609	262	V>G		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
CA53511183 rs1011377843	262	V>L		No	ClinGen TOPMed gnomAD
rs760123201 CA1826185	264	S>G		No	ClinGen ExAC gnomAD
CA348070562 rs1305195434	264	S>N		No	ClinGen TOPMed
CA348070526 rs1227388973	265	M>T		No	ClinGen TOPMed
rs777344796 CA1826183	265	M>V		No	ClinGen ExAC gnomAD
rs1386150958 CA348070496	267	E>K	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen NCI-TCGA gnomAD
CA348070480 rs1368286211	268	V>I		No	ClinGen TOPMed gnomAD
CA1826180 rs201356578	271	G>R		No	ClinGen ESP ExAC TOPMed gnomAD
CA1826179 rs768387357	272	N>I		No	ClinGen ExAC gnomAD
rs1466429895 CA348070403	272	N>K		No	ClinGen gnomAD
rs192464207 CA1826176 CA1826177	273	K>N		No	ClinGen 1000Genomes ESP TOPMed
rs938030882 CA53511158	273	K>Q		No	ClinGen TOPMed gnomAD
CA53511115 rs932204365	274	M>I		No	ClinGen TOPMed gnomAD
rs1174472877 CA348070383	274	M>T		No	ClinGen gnomAD
CA53511127 rs369310997	274	M>V		No	ClinGen ESP
CA1826175 rs200735743	275	V>A		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
rs1299138734 CA348070365	275	V>F		No	ClinGen gnomAD
rs200735743 CA1826174	275	V>G		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
CA348070350 rs1192973620	276	K>R		No	ClinGen gnomAD
TCGA novel	277	A>D	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs1456523227 CA348070343	277	A>P		No	ClinGen gnomAD
rs1456523227 CA348070342	277	A>T		No	ClinGen gnomAD
rs368621147 CA1826172	278	R>C		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
COSM1225226 rs377202328 CA1826171 COSM1225225	278	R>H	large_intestine [Cosmic]	No	ClinGen cosmic curated ESP ExAC TOPMed gnomAD
CA348070312 rs1163301987	279	Q>E		No	ClinGen TOPMed
CA348070297 CA53511037 rs1046944748	279	Q>H		No	ClinGen TOPMed gnomAD
CA348070292 rs1232342417	280	Y>C		No	ClinGen TOPMed gnomAD
rs929419681 CA53511036	280	Y>D		No	ClinGen TOPMed gnomAD
CA348070286 rs1174032347	281	P>R		No	ClinGen TOPMed gnomAD
rs757248499 CA1826170	281	P>S		No	ClinGen ExAC gnomAD
rs751689147 CA1826169	282	W>S		No	ClinGen ExAC gnomAD
rs777805950 CA1826168	283	G>C		No	ClinGen ExAC TOPMed gnomAD
CA1826167 COSM4128101 rs758706146 COSM4128100	283	G>V	ovary [Cosmic]	No	ClinGen cosmic curated ExAC gnomAD
rs753042647 CA348070236	284	V>A		No	ClinGen ExAC TOPMed gnomAD
rs753042647 CA1826166	284	V>D		No	ClinGen ExAC TOPMed gnomAD
CA53510998 rs907560008	285	V>I		No	ClinGen TOPMed
rs753730583 CA53510980	286	Q>R		No	ClinGen Ensembl
rs755363748 CA1826144	287	V>A		No	ClinGen ExAC TOPMed gnomAD
CA53510975 rs983308452	287	V>L		No	ClinGen TOPMed
rs866192664 CA53510295	288	E>G		No	ClinGen Ensembl
CA1826143 rs754262185	288	E>Q		No	ClinGen ExAC gnomAD
rs766748820 CA1826142	289	N>H		No	ClinGen ExAC gnomAD
rs145093729 CA53510294	289	N>S		No	ClinGen 1000Genomes TOPMed gnomAD
CA1826141 rs761261255	290	E>G		No	ClinGen ExAC gnomAD
rs1353688265 CA348069871	291	N>S		No	ClinGen gnomAD
rs1412789952 CA348069858 CA348069856	292	H>Q		No	ClinGen TOPMed
rs1264431165 CA348069865	292	H>Y		No	ClinGen gnomAD
CA1826140 rs750969804	293	C>F		No	ClinGen ExAC gnomAD
CA348069850 rs1312183496	293	C>G		No	ClinGen TOPMed
CA1826137 rs373740710	294	D>E		No	ClinGen ESP ExAC TOPMed gnomAD
rs367925645 CA1826138	294	D>N		No	ClinGen ESP ExAC TOPMed gnomAD
rs759200038 CA53510257	296	V>I		No	ClinGen ExAC gnomAD
rs759200038 CA1826136 CA1826135	296	V>L		No	ClinGen ExAC gnomAD
rs1348752188 CA348069797	297	K>N		No	ClinGen TOPMed
rs1402481206 CA348069790	298	L>P		No	ClinGen gnomAD
rs370353470 CA1826133	299	R>Q		No	ClinGen ESP ExAC TOPMed gnomAD
rs776495707 CA1826134	299	R>W		No	ClinGen ExAC TOPMed gnomAD
rs1558750307 CA348069713	303	I>F		No	ClinGen Ensembl
rs773081171 CA1826131	304	C>S		No	ClinGen ExAC gnomAD
CA1826130 rs772255876	305	T>I		No	ClinGen ExAC gnomAD
rs779236901 CA1826128	306	N>S		No	ClinGen ExAC gnomAD
rs376499571 CA1826129	306	N>Y		No	ClinGen ESP ExAC TOPMed gnomAD
CA53510212 rs373404656	307	M>I		No	ClinGen ESP gnomAD
rs755275798 CA348069649	307	M>L		No	ClinGen ExAC TOPMed gnomAD
CA348069640 rs1023178029	307	M>R		No	ClinGen TOPMed gnomAD
CA53510213 rs1023178029	307	M>T		No	ClinGen TOPMed gnomAD
rs755275798 CA1826127	307	M>V		No	ClinGen ExAC TOPMed gnomAD
CA1826126 rs749559709	310	L>M		No	ClinGen ExAC TOPMed gnomAD
CA1826124 rs370905521	311	R>*		No	ClinGen ESP ExAC gnomAD
rs376222124 CA1826123	311	R>L		No	ClinGen ESP ExAC TOPMed gnomAD
rs376222124 CA1826122	311	R>Q	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen ESP ExAC NCI-TCGA TOPMed gnomAD
CA1826121 rs757859956	313	Q>H		No	ClinGen ExAC gnomAD
rs1573505325 CA348069541	314	T>I		No	ClinGen Ensembl
CA1826120 rs557989965	315	H>R		No	ClinGen 1000Genomes ExAC gnomAD
rs1433518341 CA348069503	317	R>G		No	ClinGen gnomAD
rs764809526 CA1826119	317	R>S		No	ClinGen ExAC gnomAD
CA1826118 rs759228175	318	H>N		No	ClinGen ExAC gnomAD
rs776211168 CA1826117	318	H>R		No	ClinGen ExAC gnomAD
CA53510160 rs373559304	319	Y>C		No	ClinGen ESP TOPMed gnomAD
CA348069470 rs1329599321	319	Y>N		No	ClinGen gnomAD
CA53510156 rs985327771	323	R>K		No	ClinGen TOPMed gnomAD
rs766181304 CA1826116	324	R>C		No	ClinGen ExAC gnomAD
rs187032403 CA1826114	324	R>H		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
rs187032403 CA1826115	324	R>L		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
rs772167903 CA1826113	325	C>S		No	ClinGen ExAC gnomAD
CA53510141 rs1029419771	327	L>P		No	ClinGen TOPMed gnomAD
rs892839195 CA53510134	330	M>V		No	ClinGen TOPMed
rs748191814 CA1826111	331	G>D		No	ClinGen ExAC TOPMed gnomAD
CA53510133 rs778059972	331	G>S		No	ClinGen Ensembl
CA53510132 rs748191814	331	G>V		No	ClinGen ExAC TOPMed gnomAD
rs376067010 CA53510127	332	F>I		No	ClinGen ESP
CA348069252 rs1457550490	333	T>A		No	ClinGen TOPMed gnomAD
rs1274134608 CA348069243	333	T>I		No	ClinGen gnomAD
CA1826109 rs768935896	335	V>G		No	ClinGen ExAC
rs774587897 CA1826110	335	V>M		No	ClinGen ExAC gnomAD
rs780202127 CA348069202	336	G>A		No	ClinGen ExAC gnomAD
rs780202127 CA1826107	336	G>D		No	ClinGen ExAC gnomAD
CA1826108 rs749524614	336	G>S		No	ClinGen ExAC TOPMed gnomAD
CA1826106 rs756483785	337	P>Q		No	ClinGen ExAC gnomAD
CA1826104 rs781625246	338	E>K		No	ClinGen ExAC gnomAD
rs757772072 CA1826103	339	N>K		No	ClinGen ExAC gnomAD
CA1826101 rs368794598	341	P>L		No	ClinGen ESP ExAC gnomAD
rs1232520331 CA348069110	343	S>G		No	ClinGen TOPMed
CA348069105 rs1280092087	343	S>N		No	ClinGen TOPMed
rs1232520331 CA348069109	343	S>R		No	ClinGen TOPMed
CA348067181 rs1215918833	345	Q>*		No	ClinGen gnomAD
CA348067179 rs1317623285	345	Q>R		No	ClinGen TOPMed gnomAD
TCGA novel	346	E>D	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA1826080 rs778299279	348	Y>C		No	ClinGen ExAC TOPMed gnomAD
CA348067122 rs1481731187	348	Y>H		No	ClinGen TOPMed
CA53504913 rs368171273	349	E>*		No	ClinGen ESP
rs1355982255 CA348067096	350	A>T		No	ClinGen gnomAD
rs754478852 CA1826078	351	K>Q		No	ClinGen ExAC gnomAD
CA348067074 rs1416433055	352	R>G		No	ClinGen gnomAD
TCGA novel	352	R>I	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA1826077 rs529745588	352	R>K		No	ClinGen 1000Genomes ExAC gnomAD
rs374649083 CA1826074	353	H>D		No	ClinGen ESP ExAC TOPMed gnomAD
CA1826073 rs780587213	353	H>P		No	ClinGen ExAC TOPMed gnomAD
rs374649083 CA1826075	353	H>Y		No	ClinGen ESP ExAC TOPMed gnomAD
CA348067028 rs1162158847	354	E>V		No	ClinGen TOPMed gnomAD
rs761761056 CA1826072	356	H>R		No	ClinGen ExAC gnomAD
CA1826071 rs542585892	357	G>D		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
CA1826070 rs542585892	357	G>V		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
COSM714787 CA1826067 COSM1148278 rs370265320	359	R>H	lung [Cosmic]	No	ClinGen cosmic curated 1000Genomes ESP ExAC TOPMed gnomAD
CA1826068 rs370265320	359	R>L		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
rs1261600777 CA348066914	361	R>G		No	ClinGen gnomAD
rs756469749 CA53504882	363	E>D		No	ClinGen Ensembl
rs1573413922 CA348066881	363	E>K		No	ClinGen Ensembl
rs1228378333 CA348066865	364	E>K		No	ClinGen TOPMed
TCGA novel	365	E>*	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA1826065 rs759747997	365	E>D		No	ClinGen ExAC gnomAD
CA348066812 rs1243905449	366	M>I		No	ClinGen TOPMed gnomAD
CA348066775 rs1219551309	368	Q>*		No	ClinGen gnomAD
CA348066750 rs1426265176	368	Q>H		No	ClinGen gnomAD
TCGA novel	370	F>missing	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA348066714 rs1274094142	370	F>C		No	ClinGen gnomAD
CA1826063 rs367725750	371	V>A		No	ClinGen ESP ExAC TOPMed gnomAD
rs553535786 CA53504870	371	V>M		No	ClinGen 1000Genomes
CA1826062 rs771261282	373	R>*	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen ExAC NCI-TCGA gnomAD
CA348066661 rs1277421601	373	R>Q		No	ClinGen gnomAD
CA1826061 rs747413593	374	V>E		No	ClinGen ExAC gnomAD
rs995165591 CA53504850	374	V>I		No	ClinGen Ensembl
rs1558709332 CA348066620	375	K>N		No	ClinGen Ensembl
rs755586943	375	K>R	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	NCI-TCGA
CA1826058 rs772478817	378	E>K		No	ClinGen ExAC gnomAD
rs748774969 CA1826057	379	A>T		No	ClinGen ExAC TOPMed gnomAD
CA53504813 rs750820118	380	I>L		No	ClinGen Ensembl
CA348066527 rs1558709081	381	L>F		No	ClinGen Ensembl
CA1826055 rs755718548	383	E>V		No	ClinGen ExAC TOPMed gnomAD
rs750089002 CA1826054	385	E>*		No	ClinGen ExAC gnomAD
rs758268447 CA1826028	388	L>I		No	ClinGen ExAC gnomAD
rs752552834 CA1826027	388	L>Q		No	ClinGen ExAC gnomAD
TCGA novel	388	L>S	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs1209347474 CA348065500	389	Q>*		No	ClinGen TOPMed gnomAD
CA348065502 rs1209347474	389	Q>K		No	ClinGen TOPMed gnomAD
rs1348572270 CA348065484	391	K>R		No	ClinGen gnomAD
CA53500442 rs1046644326	392	F>S		No	ClinGen TOPMed
CA348065455 rs1237372604	395	L>F		No	ClinGen TOPMed gnomAD
rs1237372604 CA348065456	395	L>V		No	ClinGen TOPMed gnomAD
rs1375664840 CA348065440	397	R>T		No	ClinGen gnomAD
rs1307288737 CA348065426	399	H>R		No	ClinGen gnomAD
rs1392260501 CA348065420	400	Q>*		No	ClinGen gnomAD
CA348065404 rs1376002315	402	E>*		No	ClinGen gnomAD
rs1376002315 CA348065406	402	E>K		No	ClinGen gnomAD
rs765259112 CA1826025	403	R>K		No	ClinGen ExAC gnomAD
CA348065363 rs1434641113	407	E>D		No	ClinGen TOPMed gnomAD
rs1573350698 CA348065352	409	K>E		No	ClinGen Ensembl
rs755009380 CA1826024	409	K>R		No	ClinGen ExAC gnomAD
CA53500428 rs933211433	411	R>G		No	ClinGen TOPMed
rs146905811 CA1826023	411	R>I		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
CA348065324 rs1417966575	413	L>S		No	ClinGen gnomAD
CA348065326 rs1417966575	413	L>W		No	ClinGen gnomAD
CA53500409 rs922636416	419	A>T		No	ClinGen Ensembl
rs370571392 CA53500404	420	F>V		No	ClinGen TOPMed gnomAD
CA1826022 rs766531545	421	S>P		No	ClinGen ExAC gnomAD
rs760892761 CA1826021	422	K>E		No	ClinGen ExAC TOPMed gnomAD
CA348065236 rs1187039685	426	T>A		No	ClinGen gnomAD
CA348065237 rs1187039685	426	T>P		No	ClinGen gnomAD
rs767767642 CA1826019	428	E>K		No	ClinGen ExAC TOPMed gnomAD
CA1826018 rs762276430	430	F>S		No	ClinGen ExAC gnomAD
rs1260888798 CA348065187	431	H>P		No	ClinGen gnomAD
rs774695494 CA1826017	434	S>P		No	ClinGen ExAC gnomAD
rs1319620105 CA348065128	436	L>M		No	ClinGen gnomAD
CA1826016 rs769305807	436	L>P		No	ClinGen ExAC gnomAD
CA348065115 rs1356603798	437	A>E		No	ClinGen gnomAD
rs1414601642 CA348065121	437	A>T		No	ClinGen gnomAD
rs373330436 CA1826015	438	T>A		No	ClinGen ESP ExAC TOPMed gnomAD
rs1384369265 COSM1225228 COSM1225227 CA348065094	439	G>D	large_intestine [Cosmic]	No	ClinGen cosmic curated gnomAD
TCGA novel	441	N>S	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs1573349288 CA348065058	443	R>K		No	ClinGen Ensembl
rs1169789100 CA348065039	445	D>N		No	ClinGen TOPMed
TCGA novel	446	K>N	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs1263144221 CA348065021	446	K>R		No	ClinGen TOPMed gnomAD
rs770626851 CA1826012	448	R>C		No	ClinGen ExAC TOPMed gnomAD
CA1826009 rs369053227	448	R>H		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
CA1826010 rs369053227	448	R>L		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
CA1826011 rs369053227	448	R>P		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
TCGA novel	450	N>=	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs1188681875 CA348064463	452	N>D		No	ClinGen TOPMed
CA1825971 rs763454743	452	N>S		No	ClinGen ExAC TOPMed gnomAD
rs1442336421 CA348064447	453	F>V		No	ClinGen TOPMed

No associated diseases with Q9P0V9

1 regional properties for Q9P0V9

Type	Name	Position	InterPro Accession
domain	Septin-type guanine nucleotide-binding (G) domain	63 - 331	IPR030379

Functions

		Description
EC Number
Subcellular Localization	Cytoplasm Cytoplasm, cytoskeleton Cell projection, cilium, flagellum	Detected in the annulus of the sperm flagellum and in the neck region in spermatids and mature sperm (By similarity) Using a GFP-fusion protein, detected in the nucleus
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category	No pathway information available

4 GO annotations of cellular component

Name	Definition
cell division site	The eventual plane of cell division (also known as cell cleavage or cytokinesis) in a dividing cell. In Eukaryotes, the cleavage apparatus, composed of septin structures and the actomyosin contractile ring, forms along this plane, and the mitotic, or meiotic, spindle is aligned perpendicular to the division plane. In bacteria, the cell division site is generally located at mid-cell and is the site at which the cytoskeletal structure, the Z-ring, assembles.
microtubule cytoskeleton	The part of the cytoskeleton (the internal framework of a cell) composed of microtubules and associated proteins.
septin complex	A protein complex containing septins. Typically, these complexes contain multiple septins and are oligomeric.
septin ring	A tight ring-shaped structure that forms in the division plane at the site of cytokinesis; composed of members of the conserved family of filament-forming proteins called septins as well as septin-associated proteins. This type of septin structure is observed at the bud neck of budding fungal cells, at the site of cell division in animal cells, at the junction between the mother cell and a pseudohyphal projection, and also within hyphae of filamentous fungi at sites where a septum will form.

3 GO annotations of molecular function

Name	Definition
GTP binding	Binding to GTP, guanosine triphosphate.
GTPase activity	Catalysis of the reaction: GTP + H2O = GDP + H+ + phosphate.
molecular adaptor activity	The binding activity of a molecule that brings together two or more molecules through a selective, non-covalent, often stoichiometric interaction, permitting those molecules to function in a coordinated way.

2 GO annotations of biological process

Name	Definition
cytoskeleton-dependent cytokinesis	A cytokinesis that involves the function of a set of proteins that are part of the microfilament or microtubule cytoskeleton.
protein localization	Any process in which a protein is transported to, or maintained in, a specific location.

20 homologous proteins in AiPD

UniProt AC	Gene Name	Protein Name	Species	Evidence Code
P32468	CDC12	Cell division control protein 12	Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)	PR
Q07657	SHS1	Seventh homolog of septin 1	Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)	PR
P32457	CDC3	Cell division control protein 3	Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)	PR
A2VE99	SEPTIN11	Septin-11	Bos taurus (Bovine)	PR
A6QQL3	SEPTIN14	Septin-14	Bos taurus (Bovine)	PR
Q3SZN0	SEPTIN6	Septin-6	Bos taurus (Bovine)	PR
P54359	02-Sep	Septin-2	Drosophila melanogaster (Fruit fly)	PR
Q16181	SEPTIN7	Septin-7	Homo sapiens (Human)	PR
Q14141	SEPTIN6	Septin-6	Homo sapiens (Human)	PR
Q9NVA2	SEPTIN11	Septin-11	Homo sapiens (Human)	PR
Q9UH03	SEPTIN3	Neuronal-specific septin-3	Homo sapiens (Human)	PR
Q9UHD8	SEPTIN9	Septin-9	Homo sapiens (Human)	PR
Q8C1B7	Septin11	Septin-11	Mus musculus (Mouse)	PR
Q8CHH9	Septin8	Septin-8	Mus musculus (Mouse)	PR
Q9DA97	Septin14	Septin-14	Mus musculus (Mouse)	PR
Q9R1T4	Septin6	Septin-6	Mus musculus (Mouse)	PR
B0BNF1	Septin8	Septin-8	Rattus norvegicus (Rat)	PR
B3GNI6	Septin11	Septin-11	Rattus norvegicus (Rat)	PR
A4FUM1	sept8b	Septin-8-B	Danio rerio (Zebrafish) (Brachydanio rerio)	PR
Q642H3	sept8a	Septin-8-A	Danio rerio (Zebrafish) (Brachydanio rerio)	PR

10	20	30	40	50	60
MASSEVARHL	LFQSHMATKT	TCMSSQGSDD	EQIKRENIRS	LTMSGHVGFE	SLPDQLVNRS
70	80	90	100	110	120
IQQGFCFNIL	CVGETGIGKS	TLIDTLFNTN	FEDYESSHFC	PNVKLKAQTY	ELQESNVQLK
130	140	150	160	170	180
LTIVNTVGFG	DQINKEESYQ	PIVDYIDAQF	EAYLQEELKI	KRSLFTYHDS	RIHVCLYFIS
190	200	210	220	230	240
PTGHSLKTLD	LLTMKNLDSK	VNIIPVIAKA	DTVSKTELQK	FKIKLMSELV	SNGVQIYQFP
250	260	270	280	290	300
TDDDTIAKVN	AAMNGQLPFA	VVGSMDEVKV	GNKMVKARQY	PWGVVQVENE	NHCDFVKLRE
310	320	330	340	350	360
MLICTNMEDL	REQTHTRHYE	LYRRCKLEEM	GFTDVGPENK	PVSVQETYEA	KRHEFHGERQ
370	380	390	400	410	420
RKEEEMKQMF	VQRVKEKEAI	LKEAERELQA	KFEHLKRLHQ	EERMKLEEKR	RLLEEEIIAF
430	440	450
SKKKATSEIF	HSQSFLATGS	NLRKDKDRKN	SNFL