Q9N2K7

PR
Gene name
tbx-30 (Y59E9AR.3;, tbx-42, Y59E9AR.5)
Protein name
Putative T-box protein 30/42
Names
Species
Caenorhabditis elegans
KEGG Pathway
cel:CELE_Y59E9AR.5
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

43-296 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q9N2K7

Entry ID Method Resolution Chain Position Source
AF-Q9N2K7-F1 Predicted AlphaFoldDB

No variants for Q9N2K7

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q9N2K7

No associated diseases with Q9N2K7

2 regional properties for Q9N2K7

Type Name Position InterPro Accession
conserved_site Transcription factor, T-box, conserved site 93 - 111 IPR018186
domain T-box transcription factor, DNA-binding domain 6 - 196 IPR046360

Functions

Description
EC Number
Subcellular Localization
  • Nucleus
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
nucleus A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.

2 GO annotations of molecular function

Name Definition
DNA-binding transcription factor activity, RNA polymerase II-specific A DNA-binding transcription factor activity that modulates the transcription of specific gene sets transcribed by RNA polymerase II.
RNA polymerase II cis-regulatory region sequence-specific DNA binding Binding to a specific upstream regulatory DNA sequence (transcription factor recognition sequence or binding site) located in cis relative to the transcription start site (i.e., on the same strand of DNA) of a gene transcribed by RNA polymerase II.

3 GO annotations of biological process

Name Definition
cell fate specification The process involved in the specification of cell identity. Once specification has taken place, a cell will be committed to differentiate down a specific pathway if left in its normal environment.
positive regulation of DNA-templated transcription Any process that activates or increases the frequency, rate or extent of cellular DNA-templated transcription.
regulation of transcription by RNA polymerase II Any process that modulates the frequency, rate or extent of transcription mediated by RNA polymerase II.

8 homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
P79779 TBX6L T-box-containing protein TBX6L Gallus gallus (Chicken) PR
Q13207 TBX2 T-box transcription factor TBX2 Homo sapiens (Human) PR
Q16650 TBR1 T-box brain protein 1 Homo sapiens (Human) PR
Q60707 Tbx2 T-box transcription factor TBX2 Mus musculus (Mouse) PR
Q64336 Tbr1 T-box brain protein 1 Mus musculus (Mouse) PR
Q810F8 Tbx10 T-box transcription factor TBX10 Mus musculus (Mouse) PR
Q20257 tbx-11 Putative T-box protein 11 Caenorhabditis elegans PR
Q22289 tbx-9 T-box transcription factor tbx-9 Caenorhabditis elegans PR
10 20 30 40 50 60
MNPSTQIVVK MSNEELWKER YPNMEMISNS KRITPIFPEI KFKISGLEEN SRYVLVLSLE
70 80 90 100 110 120
KMDNIRYGIN ENKEWAPSSA RKPKPHHNMK FFFHPEGTKL GKELMAETVE FTSVRITTSE
130 140 150 160 170 180
KLSEKENVFY VHTMHKYVPV LTIRNLTTGE IASNIFKMEI AQFFPVSIYQ QASMGRWKSD
190 200 210 220 230 240
LNKHSTFGNR SEGGIKRKTS DAAGQLPSKR SSKKPVKKDV VDNSEVTLEV KTSQYLVNQN
250 260 270 280 290 300
ESNLTEYIPS SPLYSSQNQY QYPFHPYSPF DSSIPYPYSP MDYSYYFNPT FQSFSPENVY
FDENRNPH