| aorta morphogenesis |
The process in which the anatomical structures of an aorta are generated and organized. An aorta is an artery that carries blood from the heart to other parts of the body. |
| apoptotic process |
A programmed cell death process which begins when a cell receives an internal (e.g. DNA damage) or external signal (e.g. an extracellular death ligand), and proceeds through a series of biochemical events (signaling pathway phase) which trigger an execution phase. The execution phase is the last step of an apoptotic process, and is typically characterized by rounding-up of the cell, retraction of pseudopodes, reduction of cellular volume (pyknosis), chromatin condensation, nuclear fragmentation (karyorrhexis), plasma membrane blebbing and fragmentation of the cell into apoptotic bodies. When the execution phase is completed, the cell has died. |
| atrioventricular canal development |
The progression of the atrioventricular canal over time, from its formation to the mature structure. The atrioventricular canal is the part of the heart connecting the atrium to the cardiac ventricle. |
| atrioventricular canal morphogenesis |
The developmental process by which an atrioventricular canal is generated and organized. |
| cardiac jelly development |
The process whose specific outcome is the progression of cardiac jelly over time, from its formation to the mature structure. The cardiac jelly is an acellular gelatinous matrix secreted by the myocardium and plays a central role in the septation of the heart. |
| cardiac muscle cell myoblast differentiation |
The process in which a relatively unspecialized cell acquires specialized features of a cardiac myoblast. A cardiac myoblast is a precursor cell that has been committed to a cardiac muscle cell fate but retains the ability to divide and proliferate throughout life. |
| cardiac muscle tissue development |
The process whose specific outcome is the progression of cardiac muscle over time, from its formation to the mature structure. |
| cell fate specification |
The process involved in the specification of cell identity. Once specification has taken place, a cell will be committed to differentiate down a specific pathway if left in its normal environment. |
| cellular senescence |
A cell aging process stimulated in response to cellular stress, whereby normal cells lose the ability to divide through irreversible cell cycle arrest. |
| cochlea morphogenesis |
The process in which the cochlea is generated and organized. |
| developmental growth involved in morphogenesis |
The increase in size or mass of an anatomical structure that contributes to the structure attaining its shape. |
| embryonic camera-type eye morphogenesis |
The process in which the anatomical structures of the eye are generated and organized during embryonic development. |
| embryonic digit morphogenesis |
The process, occurring in the embryo, by which the anatomical structures of the digit are generated and organized. A digit is one of the terminal divisions of an appendage, such as a finger or toe. |
| embryonic heart tube development |
The process whose specific outcome is the progression of the embryonic heart tube over time, from its formation to the mature structure. The heart tube forms as the heart rudiment from the heart field. |
| endocardial cushion formation |
The developmental process pertaining to the initial formation of an endocardial cushion. The endocardial cushion is a specialized region of mesenchymal cells that will give rise to the heart septa and valves. |
| endocardial cushion morphogenesis |
The process in which the anatomical structure of the endocardial cushion is generated and organized. The endocardial cushion is a specialized region of mesenchymal cells that will give rise to the heart septa and valves. |
| epithelial tube branching involved in lung morphogenesis |
The process in which a highly ordered sequence of patterning events generates the branched epithelial tubes of the lung, consisting of reiterated combinations of bud outgrowth, elongation, and dichotomous subdivision of terminal units. |
| fibroblast growth factor receptor signaling pathway |
The series of molecular signals generated as a consequence of a fibroblast growth factor receptor binding to one of its physiological ligands. |
| heart looping |
The tube morphogenesis process in which the primitive heart tube loops asymmetrically. This looping brings the primitive heart chambers into alignment preceding their future integration. Heart looping begins with dextral-looping and ends when the main regional divisions of the mature heart and primordium of the great arterial trunks become established preceeding septation. |
| heart morphogenesis |
The developmental process in which the heart is generated and organized. The heart is a hollow, muscular organ, which, by contracting rhythmically, keeps up the circulation of the blood. |
| mammary placode formation |
The developmental process in which the mammary placode forms. The mammary placode is a transient lens shaped structure that will give rise to the mammary bud proper. |
| melanocyte proliferation |
The multiplication or reproduction of melanocytes, resulting in the expansion of a cell population. A melanocyte is a pigment cell derived from the neural crest. It contains melanin-filled pigment granules, which give a brown to black appearance. |
| mesenchymal cell proliferation involved in lung development |
The multiplication or reproduction of cells, resulting in the expansion of a mesenchymal cell population that contributes to the progression of the lung over time. A mesenchymal cell is a cell that normally gives rise to other cells that are organized as three-dimensional masses, rather than sheets. |
| muscle cell fate determination |
The cell fate determination process in which a cell becomes capable of differentiating autonomously into a muscle cell regardless of its environment; upon determination, the cell fate cannot be reversed. |
| negative regulation of cardiac chamber formation |
Any process that stops, prevents or reduces the frequency, rate or extent of cardiac chamber formation. |
| negative regulation of cellular senescence |
Any process that stops, prevents or reduces the frequency, rate or extent of cellular senescence. |
| negative regulation of DNA-templated transcription |
Any process that stops, prevents, or reduces the frequency, rate or extent of cellular DNA-templated transcription. |
| negative regulation of heart looping |
Any process that stops, prevents or reduces the frequency, rate or extent of heart looping. |
| negative regulation of transcription by RNA polymerase II |
Any process that stops, prevents, or reduces the frequency, rate or extent of transcription mediated by RNA polymerase II. |
| neurogenesis |
Generation of cells within the nervous system. |
| Notch signaling pathway |
The series of molecular signals initiated by an extracellular ligand binding to the receptor Notch on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription. |
| outflow tract morphogenesis |
The process in which the anatomical structures of the outflow tract are generated and organized. The outflow tract is the portion of the heart through which blood flows into the arteries. |
| outflow tract septum morphogenesis |
The process in which the anatomical structures of the outflow tract septum are generated and organized. The outflow tract septum is a partition in the outflow tract. |
| pharynx development |
The biological process whose specific outcome is the progression of a pharynx from an initial condition to its mature state. The pharynx is the part of the digestive system immediately posterior to the mouth. |
| pigment metabolic process involved in pigmentation |
The chemical reactions and pathways involving a pigment, any general or particular coloring matter in living organisms, resulting in the deposition or aggregation of pigment in an organism, tissue or cell. |
| positive regulation of cardiac muscle cell proliferation |
Any process that activates or increases the frequency, rate or extent of cardiac muscle cell proliferation. |
| positive regulation of cell cycle G1/S phase transition |
Any signalling pathway that activates or increases the activity of a cell cycle cyclin-dependent protein kinase to modulate the switch from G1 phase to S phase of the cell cycle. |
| positive regulation of transcription by RNA polymerase II |
Any process that activates or increases the frequency, rate or extent of transcription from an RNA polymerase II promoter. |
| regulation of heart contraction |
Any process that modulates the frequency, rate or extent of heart contraction. Heart contraction is the process in which the heart decreases in volume in a characteristic way to propel blood through the body. |
| regulation of transcription by RNA polymerase II |
Any process that modulates the frequency, rate or extent of transcription mediated by RNA polymerase II. |
| response to retinoic acid |
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a retinoic acid stimulus. |
| roof of mouth development |
The biological process whose specific outcome is the progression of the roof of the mouth from an initial condition to its mature state. This process begins with the formation of the structure and ends with the mature structure. The roof of the mouth is the partition that separates the nasal and oral cavities. |
| smooth muscle cell differentiation |
The process in which a relatively unspecialized cell acquires specialized features of a smooth muscle cell; smooth muscle lacks transverse striations in its constituent fibers and are almost always involuntary. |
| ureteric peristalsis |
A wavelike sequence of involuntary muscular contraction and relaxation that passes along the ureter, impelling the contents onwards. The ureter is one of a pair of thick-walled tubes that transports urine from the kidney pelvis to the urinary bladder. |
