Q9M0G9
PR
Gene name |
ABCB24 (ATM2, STA3, At4g28620, T5F17.70) |
Protein name |
ABC transporter B family member 24, mitochondrial |
Names |
ABC transporter ABCB.24, AtABCB24, ABC transporter of the mitochondrion 2, AtATM2, Iron-sulfur clusters transporter ATM2, Protein STARIK 3 |
Species |
Arabidopsis thaliana (Mouse-ear cress) |
KEGG Pathway |
ath:AT4G28620 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q9M0G9
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q9M0G9-F1 | Predicted | AlphaFoldDB |
104 variants for Q9M0G9
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| ENSVATH06791724 | 9 | L>H | No | 1000Genomes | |
| tmp_4_14137920_T_C | 12 | T>A | No | 1000Genomes | |
| ENSVATH06791720 | 36 | I>M | No | 1000Genomes | |
| ENSVATH14306729 | 44 | S>F | No | 1000Genomes | |
| ENSVATH14306729 | 44 | S>Y | No | 1000Genomes | |
| tmp_4_14137811_T_A,C | 48 | N>I | No | 1000Genomes | |
| tmp_4_14137811_T_A,C | 48 | N>S | No | 1000Genomes | |
| tmp_4_14137778_G_T | 59 | P>H | No | 1000Genomes | |
| ENSVATH06791717 | 60 | M>L | No | 1000Genomes | |
| tmp_4_14137727_T_C | 76 | H>R | No | 1000Genomes | |
| tmp_4_14137724_G_A | 77 | P>L | No | 1000Genomes | |
| ENSVATH06791716 | 82 | R>S | No | 1000Genomes | |
| tmp_4_14137698_C_G | 86 | E>Q | No | 1000Genomes | |
| ENSVATH06791714 | 90 | R>G | No | 1000Genomes | |
| ENSVATH06791714 | 90 | R>W | No | 1000Genomes | |
| tmp_4_14137671_A_T | 95 | Y>N | No | 1000Genomes | |
| ENSVATH12279280 | 112 | F>S | No | 1000Genomes | |
| tmp_4_14137594_G_T | 120 | F>L | No | 1000Genomes | |
| tmp_4_14137563_C_G | 131 | V>L | No | 1000Genomes | |
| ENSVATH06791712 | 141 | F>S | No | 1000Genomes | |
| ENSVATH12279277 | 149 | V>L | No | 1000Genomes | |
| ENSVATH06791710 | 154 | T>P | No | 1000Genomes | |
| ENSVATH06791709 | 155 | P>T | No | 1000Genomes | |
| ENSVATH06791708 | 161 | G>A | No | 1000Genomes | |
| ENSVATH06791708 | 161 | G>V | No | 1000Genomes | |
| ENSVATH06791705 | 178 | S>N | No | 1000Genomes | |
| ENSVATH06791704 | 181 | S>F | No | 1000Genomes | |
| ENSVATH12279276 | 189 | R>Q | No | 1000Genomes | |
| ENSVATH06791703 | 194 | K>N | No | 1000Genomes | |
| tmp_4_14137355_T_C | 200 | H>R | No | 1000Genomes | |
| ENSVATH06791701 | 211 | D>E | No | 1000Genomes | |
| ENSVATH06791700 | 233 | M>I | No | 1000Genomes | |
| ENSVATH06791698 | 238 | M>I | No | 1000Genomes | |
| ENSVATH06791699 | 238 | M>V | No | 1000Genomes | |
| tmp_4_14137235_G_T | 240 | T>K | No | 1000Genomes | |
| ENSVATH06791697 | 249 | C>S | No | 1000Genomes | |
| ENSVATH06791696 | 269 | S>* | No | 1000Genomes | |
| tmp_4_14137127_G_A | 276 | A>V | No | 1000Genomes | |
| tmp_4_14137125_T_C | 277 | M>V | No | 1000Genomes | |
| tmp_4_14137115_C_T | 280 | W>* | No | 1000Genomes | |
| tmp_4_14137114_C_A | 280 | W>C | No | 1000Genomes | |
| tmp_4_14137109_A_G | 282 | I>T | No | 1000Genomes | |
| tmp_4_14137104_T_A | 284 | I>F | No | 1000Genomes | |
| tmp_4_14137094_G_C | 287 | A>G | No | 1000Genomes | |
| ENSVATH06791694 | 289 | N>S | No | 1000Genomes | |
| ENSVATH06791693 | 300 | I>V | No | 1000Genomes | |
| tmp_4_14137044_T_C | 304 | I>V | No | 1000Genomes | |
| tmp_4_14137009_T_G | 315 | E>D | No | 1000Genomes | |
| tmp_4_14137003_G_T | 317 | Y>* | No | 1000Genomes | |
| ENSVATH02935559 | 324 | Q>R | No | 1000Genomes | |
| tmp_4_14136956_G_T | 333 | A>E | No | 1000Genomes | |
| tmp_4_14136957_C_T | 333 | A>T | No | 1000Genomes | |
| ENSVATH12279275 | 335 | Q>E | No | 1000Genomes | |
| tmp_4_14136950_T_C | 335 | Q>R | No | 1000Genomes | |
| ENSVATH06791688 | 343 | L>V | No | 1000Genomes | |
| ENSVATH06791687 | 345 | F>V | No | 1000Genomes | |
| tmp_4_14136917_C_A | 346 | G>V | No | 1000Genomes | |
| ENSVATH14306727 | 347 | Q>K | No | 1000Genomes | |
| ENSVATH06791686 | 348 | S>N | No | 1000Genomes | |
| tmp_4_14136907_A_T | 349 | F>L | No | 1000Genomes | |
| ENSVATH06791684 | 352 | S>N | No | 1000Genomes | |
| tmp_4_14136855_T_C | 367 | M>V | No | 1000Genomes | |
| tmp_4_14136816_T_A | 380 | N>Y | No | 1000Genomes | |
| ENSVATH12279264 | 381 | G>S | No | 1000Genomes | |
| tmp_4_14136722_A_C | 411 | F>C | No | 1000Genomes | |
| ENSVATH06791679 | 412 | K>T | No | 1000Genomes | |
| ENSVATH06791678 | 413 | F>L | No | 1000Genomes | |
| tmp_4_14136704_C_A | 417 | R>I | No | 1000Genomes | |
| tmp_4_14136699_C_T | 419 | D>N | No | 1000Genomes | |
| tmp_4_14136680_A_G | 425 | I>T | No | 1000Genomes | |
| tmp_4_14136676_G_C | 426 | D>E | No | 1000Genomes | |
| tmp_4_14136674_C_G | 427 | R>T | No | 1000Genomes | |
| ENSVATH02935558 | 438 | S>N | No | 1000Genomes | |
| ENSVATH06791677 | 439 | I>T | No | 1000Genomes | |
| ENSVATH06791672 | 461 | E>V | No | 1000Genomes | |
| ENSVATH12279263 | 463 | P>S | No | 1000Genomes | |
| tmp_4_14136564_C_G | 464 | A>P | No | 1000Genomes | |
| ENSVATH12279262 | 481 | I>S | No | 1000Genomes | |
| tmp_4_14136494_C_T | 487 | R>K | No | 1000Genomes | |
| tmp_4_14136479_T_C | 492 | D>G | No | 1000Genomes | |
| ENSVATH06791668 | 494 | G>R | No | 1000Genomes | |
| ENSVATH00542976 | 501 | Q>E | No | 1000Genomes | |
| ENSVATH14306725 | 507 | R>T | No | 1000Genomes | |
| ENSVATH06791667 | 514 | S>C | No | 1000Genomes | |
| tmp_4_14136398_G_C | 519 | P>R | No | 1000Genomes | |
| tmp_4_14135967_G_T | 534 | H>Q | No | 1000Genomes | |
| ENSVATH06791646 | 547 | N>D | No | 1000Genomes | |
| tmp_4_14135867_C_G | 568 | A>P | No | 1000Genomes | |
| tmp_4_14135819_C_T | 584 | V>M | No | 1000Genomes | |
| ENSVATH06791640 | 602 | A>V | No | 1000Genomes | |
| ENSVATH14306722 | 611 | E>K | No | 1000Genomes | |
| ENSVATH14306721 | 620 | S>L | No | 1000Genomes | |
| tmp_4_14135689_C_T | 627 | C>Y | No | 1000Genomes | |
| ENSVATH06791632 | 637 | A>S | No | 1000Genomes | |
| tmp_4_14135655_C_T | 638 | M>I | No | 1000Genomes | |
| tmp_4_14135648_C_A | 641 | D>Y | No | 1000Genomes | |
| tmp_4_14135639_A_T | 644 | L>I | No | 1000Genomes | |
| ENSVATH12279192 | 645 | V>A | No | 1000Genomes | |
| ENSVATH02935555 | 658 | E>Q | No | 1000Genomes | |
| tmp_4_14135584_C_T | 662 | G>E | No | 1000Genomes | |
| tmp_4_14135566_G_A | 668 | A>V | No | 1000Genomes | |
| ENSVATH00542972 | 678 | L>M | No | 1000Genomes | |
| ENSVATH06791628 | 680 | V>G | No | 1000Genomes | |
| ENSVATH14306720 | 681 | V>W | No | 1000Genomes |
No associated diseases with Q9M0G9
1 regional properties for Q9M0G9
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| domain | Septin-type guanine nucleotide-binding (G) domain | 63 - 331 | IPR030379 |
3 GO annotations of cellular component
| Name | Definition |
|---|---|
| integral component of membrane | The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane. |
| mitochondrial inner membrane | The inner, i.e. lumen-facing, lipid bilayer of the mitochondrial envelope. It is highly folded to form cristae. |
| mitochondrion | A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration. |
3 GO annotations of molecular function
| Name | Definition |
|---|---|
| ABC-type transporter activity | Primary active transporter characterized by two nucleotide-binding domains and two transmembrane domains. Uses the energy generated from ATP hydrolysis to drive the transport of a substance across a membrane. |
| ATP binding | Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator. |
| ATPase-coupled transmembrane transporter activity | Primary active transporter of a solute across a membrane, via the reaction: ATP + H2O = ADP + phosphate, to directly drive the transport of a substance across a membrane. The transport protein may be transiently phosphorylated (P-type transporters), or not (ABC-type transporters and other families of transporters). Primary active transport occurs up the solute's concentration gradient and is driven by a primary energy source. |
4 GO annotations of biological process
| Name | Definition |
|---|---|
| cellular iron ion homeostasis | Any process involved in the maintenance of an internal steady state of iron ions at the level of a cell. |
| ion transport | The directed movement of charged atoms or small charged molecules into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. |
| response to cadmium ion | Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cadmium (Cd) ion stimulus. |
| transmembrane transport | The process in which a solute is transported across a lipid bilayer, from one side of a membrane to the other. |
8 homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| P40416 | ATM1 | Iron-sulfur clusters transporter ATM1, mitochondrial | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) | PR |
| Q9NP58 | ABCB6 | ATP-binding cassette sub-family B member 6 | Homo sapiens (Human) | PR |
| Q9DC29 | Abcb6 | ATP-binding cassette sub-family B member 6 | Mus musculus (Mouse) | PR |
| O70595 | Abcb6 | ATP-binding cassette sub-family B member 6 | Rattus norvegicus (Rat) | PR |
| Q9FUT3 | ABCB23 | ABC transporter B family member 23, mitochondrial | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q9LVM1 | ABCB25 | ABC transporter B family member 25, mitochondrial | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q9LJX0 | ABCB19 | ABC transporter B family member 19 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q9ZR72 | ABCB1 | ABC transporter B family member 1 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| 10 | 20 | 30 | 40 | 50 | 60 |
| MMRVSQLQLC | RTSLSYRLRS | GYHHHHHLHH | SFFKLIKRNS | ILESPPTNAS | HQSPSPITPM |
| 70 | 80 | 90 | 100 | 110 | 120 |
| VNARVMFFST | STSAPHPEKI | NRTSSENILR | MISSYLWMKD | NPKLCFRVIS | AFACLVGAKF |
| 130 | 140 | 150 | 160 | 170 | 180 |
| LNVQVPFLFK | VAIDWLSSSS | FVDSNPYLVA | AFATPSSVLI | GYGIARSGSS | AFNELRTSVF |
| 190 | 200 | 210 | 220 | 230 | 240 |
| SKVALRTIRT | ISRKVLSRLH | DLDLRYHLNR | DTGALNRIID | RGSRAINTIL | SAMVFNIMPT |
| 250 | 260 | 270 | 280 | 290 | 300 |
| ILEISMVSCI | LAYKFGAVYA | LITCLSVGSY | IAFTLAMTQW | RIKIRKAMNE | AENDASTRAI |
| 310 | 320 | 330 | 340 | 350 | 360 |
| DSLINYETVK | YFNNEDYEAR | KYDQLHENYE | DAALQSRKSF | ALLNFGQSFI | FSTALSTAMV |
| 370 | 380 | 390 | 400 | 410 | 420 |
| LCSQGIMNGQ | MTVGDLVMVN | GLLFQLSLPL | YFLGVVYSDT | VQGLVDMKSM | FKFLEERSDI |
| 430 | 440 | 450 | 460 | 470 | 480 |
| GDKDIDRKLP | PLVLKGGSIS | FENVHFSYLP | ERKILDGISF | EVPAGKSVAI | VGSSGSGKST |
| 490 | 500 | 510 | 520 | 530 | 540 |
| ILRMIFRFFD | VDSGNVKIDG | QDIKEVRLES | LRSSIGVVPQ | DTVLFNDTIF | HNIHYGNLSA |
| 550 | 560 | 570 | 580 | 590 | 600 |
| TEEEVYNAAR | RAAIHDTIMK | FPDKYSTAVG | ERGLMLSGGE | KQRVALARAF | LKSPAILLCD |
| 610 | 620 | 630 | 640 | 650 | 660 |
| EATSALDSKT | EAEIMKTLRS | LASNRTCIFI | AHRLTTAMQC | DEILVMEKGK | VVEKGTHEVL |
| 670 | |||||
| LGKSGRYAKL | WTQQNSKLEV |