Q9FUT3

PR
Gene name
ABCB23 (ATM1, STA2, At4g28630, T5F17.80)
Protein name
ABC transporter B family member 23, mitochondrial
Names
ABC transporter ABCB.23, AtABCB23, ABC transporter of the mitochondrion 1, AtATM1, Iron-sulfur clusters transporter ATM1, Protein STARIK 2
Species
Arabidopsis thaliana (Mouse-ear cress)
KEGG Pathway
ath:AT4G28630
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-113 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q9FUT3

Entry ID Method Resolution Chain Position Source
AF-Q9FUT3-F1 Predicted AlphaFoldDB

47 variants for Q9FUT3

Variant ID(s) Position Change Description Diseaes Association Provenance
tmp_4_14140890_C_T 2 M>I No 1000Genomes
ENSVATH14306741 2 M>V No 1000Genomes
ENSVATH06791792 24 H>R No 1000Genomes
tmp_4_14140815_G_T 27 F>L No 1000Genomes
tmp_4_14140785_C_A 37 Q>H No 1000Genomes
ENSVATH06791791 43 N>Y No 1000Genomes
ENSVATH00542983 46 F>I No 1000Genomes
ENSVATH12279333 49 P>T No 1000Genomes
tmp_4_14140739_G_T 53 P>T No 1000Genomes
tmp_4_14140730_C_T 56 V>I No 1000Genomes
ENSVATH14306740 79 S>P No 1000Genomes
ENSVATH06791788 100 R>Q No 1000Genomes
ENSVATH06791787 105 A>S No 1000Genomes
ENSVATH02935568 134 Y>S No 1000Genomes
ENSVATH06791785 146 L>P No 1000Genomes
ENSVATH14306738 151 A>S No 1000Genomes
tmp_4_14140388_A_T 170 F>I No 1000Genomes
tmp_4_14140367_C_T 177 V>I No 1000Genomes
tmp_4_14140114_G_T 261 T>N No 1000Genomes
tmp_4_14140076_C_T 274 V>I No 1000Genomes
tmp_4_14140043_C_T 285 A>T No 1000Genomes
ENSVATH14306737 388 L>R No 1000Genomes
ENSVATH06791782 405 M>I No 1000Genomes
tmp_4_14139628_G_C 423 T>R No 1000Genomes
ENSVATH02935565 462 A>S No 1000Genomes
ENSVATH12279327 490 D>N No 1000Genomes
tmp_4_14139416_C_T 494 V>I No 1000Genomes
tmp_4_14139397_T_G 500 D>A No 1000Genomes
tmp_4_14139375_C_A 507 E>D No 1000Genomes
ENSVATH12279313 541 E>K No 1000Genomes
tmp_4_14138891_C_T 561 D>N No 1000Genomes
ENSVATH14306735 564 S>W No 1000Genomes
ENSVATH06791760 566 A>T No 1000Genomes
tmp_4_14138858_G_T 572 L>M No 1000Genomes
ENSVATH02935563 584 L>F No 1000Genomes
ENSVATH06791756 602 N>S No 1000Genomes
ENSVATH12279311
ENSVATH12279310
 616 F>L No 1000Genomes
tmp_4_14138691_G_C 627 F>L No 1000Genomes
tmp_4_14138661_T_G 637 Q>H No 1000Genomes
tmp_4_14138650_A_G 641 I>T No 1000Genomes
tmp_4_14138648_T_A 642 I>L No 1000Genomes
tmp_4_14138646_T_C 642 I>M No 1000Genomes
ENSVATH06791746 656 Q>E No 1000Genomes
ENSVATH06791744 660 E>G No 1000Genomes
ENSVATH14306734 660 E>K No 1000Genomes
tmp_4_14138558_G_A 672 Q>* No 1000Genomes
ENSVATH14306733 676 L>Q No 1000Genomes

No associated diseases with Q9FUT3

4 regional properties for Q9FUT3

Type Name Position InterPro Accession
domain ABC transporter-like, ATP-binding domain 437 - 671 IPR003439
domain AAA+ ATPase domain 462 - 648 IPR003593
domain ABC transporter type 1, transmembrane domain 103 - 400 IPR011527
conserved_site ABC transporter-like, conserved site 574 - 588 IPR017871

Functions

Description
EC Number
Subcellular Localization
  • Mitochondrion inner membrane ; Multi-pass membrane protein
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

3 GO annotations of cellular component

Name Definition
integral component of membrane The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
mitochondrial inner membrane The inner, i.e. lumen-facing, lipid bilayer of the mitochondrial envelope. It is highly folded to form cristae.
mitochondrion A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.

3 GO annotations of molecular function

Name Definition
ABC-type transporter activity Primary active transporter characterized by two nucleotide-binding domains and two transmembrane domains. Uses the energy generated from ATP hydrolysis to drive the transport of a substance across a membrane.
ATP binding Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
ATPase-coupled transmembrane transporter activity Primary active transporter of a solute across a membrane, via the reaction: ATP + H2O = ADP + phosphate, to directly drive the transport of a substance across a membrane. The transport protein may be transiently phosphorylated (P-type transporters), or not (ABC-type transporters and other families of transporters). Primary active transport occurs up the solute's concentration gradient and is driven by a primary energy source.

4 GO annotations of biological process

Name Definition
cellular iron ion homeostasis Any process involved in the maintenance of an internal steady state of iron ions at the level of a cell.
ion transport The directed movement of charged atoms or small charged molecules into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
response to cadmium ion Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cadmium (Cd) ion stimulus.
transmembrane transport The process in which a solute is transported across a lipid bilayer, from one side of a membrane to the other.

8 homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
P40416 ATM1 Iron-sulfur clusters transporter ATM1, mitochondrial Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) PR
Q9NP58 ABCB6 ATP-binding cassette sub-family B member 6 Homo sapiens (Human) PR
Q9DC29 Abcb6 ATP-binding cassette sub-family B member 6 Mus musculus (Mouse) PR
O70595 Abcb6 ATP-binding cassette sub-family B member 6 Rattus norvegicus (Rat) PR
Q9LVM1 ABCB25 ABC transporter B family member 25, mitochondrial Arabidopsis thaliana (Mouse-ear cress) PR
Q9M0G9 ABCB24 ABC transporter B family member 24, mitochondrial Arabidopsis thaliana (Mouse-ear cress) PR
Q9LJX0 ABCB19 ABC transporter B family member 19 Arabidopsis thaliana (Mouse-ear cress) PR
Q9ZR72 ABCB1 ABC transporter B family member 1 Arabidopsis thaliana (Mouse-ear cress) PR
10 20 30 40 50 60
MMRGSRFLLS RASLYHRLRS DHHHHSFSSF IKRSSIQRSP AINAFFTDPS PSPSPVNARV
70 80 90 100 110 120
FFFSTSTSTP NQDQTKTASS KKILRTISSY LWMKDNPELR FRVIAALACL IGAKFLNVQV
130 140 150 160 170 180
PFLFKLSIDL LSSYSSSTIT DSNPYLLAAF ATPSSVLIGY GIARSGSSAF NELRTAVFSK
190 200 210 220 230 240
VSLRTIRSVS RKVLSHLHDL DLRYHLNRET GALNRIIDRG SRAINTILSA MVFNVVPTIL
250 260 270 280 290 300
EISMVTGILA YNFGPVFALI TSLSVGSYIA FTLVVTQYRT KFRKAMNQAD NDASTRAIDS
310 320 330 340 350 360
LVNYETVKYF NNEDYEARKY DDLLGRYEDA ALQTQKSLAF LDFGQSFIFS TALSTSMVLC
370 380 390 400 410 420
SQGIMNGEMT VGDLVMVNGL LFQLSLPLYF LGGVYRETVQ GLVDMKSLFQ LLEERSDIGD
430 440 450 460 470 480
KDTETKLPPL VLRGGSISFE NVHFSYLPER KILDGISFEV PAGKSVAIVG SSGSGKSTIL
490 500 510 520 530 540
RMIFRFFDTD SGNVRIDGQD IKEVTLESLR SCIGVVPQDT VLFNDTIFHN IHYGNLSATE
550 560 570 580 590 600
EEVYDAARRA VIHDTIMKFP DKYSTAVGER GLMLSGGEKQ RVALARAFLK SPAILLCDEA
610 620 630 640 650 660
TNALDSKTEA EIMKTFRSLA SNRTCIFIAH RLTTAMQCDE IIVMEKGKVV EKGTHQVLLE
670
KSGRYAKLWT QQNSTLEV