Q9FKF2
PR
Gene name |
ABCA11 (ATH15, At5g61690, K11J9.22) |
Protein name |
ABC transporter A family member 11 |
Names |
ABC transporter ABCA.11, AtABCA11, Putative ABC2 homolog 15 |
Species |
Arabidopsis thaliana (Mouse-ear cress) |
KEGG Pathway |
ath:AT5G61690 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q9FKF2
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q9FKF2-F1 | Predicted | AlphaFoldDB |
74 variants for Q9FKF2
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| tmp_5_24793483_A_C | 2 | I>S | No | 1000Genomes | |
| tmp_5_24793480_A_G | 3 | L>S | No | 1000Genomes | |
| ENSVATH07462781 | 13 | Q>* | No | 1000Genomes | |
| tmp_5_24793434_G_C | 18 | F>L | No | 1000Genomes | |
| tmp_5_24793397_C_T | 31 | A>T | No | 1000Genomes | |
| ENSVATH12898291 | 33 | C>S | No | 1000Genomes | |
| ENSVATH12898290 | 35 | Q>E | No | 1000Genomes | |
| ENSVATH03462282 | 50 | E>D | No | 1000Genomes | |
| ENSVATH00746952 | 57 | D>N | No | 1000Genomes | |
| ENSVATH12898289 | 58 | A>V | No | 1000Genomes | |
| ENSVATH03462281 | 112 | A>V | No | 1000Genomes | |
| tmp_5_24793145_G_C | 115 | P>A | No | 1000Genomes | |
| ENSVATH00746950 | 135 | T>A | No | 1000Genomes | |
| ENSVATH12898287 | 152 | E>K | No | 1000Genomes | |
| tmp_5_24792941_C_G | 159 | S>T | No | 1000Genomes | |
| tmp_5_24792846_C_A | 191 | E>* | No | 1000Genomes | |
| tmp_5_24792812_G_T | 202 | P>Q | No | 1000Genomes | |
| ENSVATH14644254 | 252 | E>* | No | 1000Genomes | |
| ENSVATH07462774 | 256 | K>* | No | 1000Genomes | |
| tmp_5_24792648_G_T | 257 | L>I | No | 1000Genomes | |
| tmp_5_24792517_A_C | 300 | D>E | No | 1000Genomes | |
| tmp_5_24792500_C_T | 306 | S>N | No | 1000Genomes | |
| tmp_5_24792492_G_T | 309 | L>I | No | 1000Genomes | |
| ENSVATH12898286 | 310 | V>I | No | 1000Genomes | |
| ENSVATH12898285 | 320 | N>S | No | 1000Genomes | |
| tmp_5_24792326_G_A | 335 | S>L | No | 1000Genomes | |
| ENSVATH00746947 | 370 | R>C | No | 1000Genomes | |
| ENSVATH03462280 | 408 | V>L | No | 1000Genomes | |
| ENSVATH12898250 | 414 | A>V | No | 1000Genomes | |
| tmp_5_24791870_T_C | 430 | T>A | No | 1000Genomes | |
| ENSVATH07462765 | 449 | S>T | No | 1000Genomes | |
| ENSVATH12898247 | 451 | V>I | No | 1000Genomes | |
| ENSVATH12898245 | 454 | P>S | No | 1000Genomes | |
| tmp_5_24791664_C_A | 475 | G>C | No | 1000Genomes | |
| tmp_5_24791639_G_A | 483 | S>L | No | 1000Genomes | |
| ENSVATH07462761 | 485 | P>S | No | 1000Genomes | |
| ENSVATH03462279 | 486 | L>P | No | 1000Genomes | |
| ENSVATH12898223 | 510 | D>N | No | 1000Genomes | |
| tmp_5_24791484_C_T | 535 | G>R | No | 1000Genomes | |
| tmp_5_24791483_C_A | 535 | G>V | No | 1000Genomes | |
| tmp_5_24791462_G_T | 542 | T>N | No | 1000Genomes | |
| tmp_5_24791299_C_A | 551 | L>F | No | 1000Genomes | |
| ENSVATH12898221 | 589 | A>T | No | 1000Genomes | |
| ENSVATH00746945 | 602 | I>M | No | 1000Genomes | |
| ENSVATH07462756 | 612 | C>R | No | 1000Genomes | |
| ENSVATH07462755 | 620 | D>N | No | 1000Genomes | |
| tmp_5_24790872_C_A | 640 | A>S | No | 1000Genomes | |
| ENSVATH14644250 | 645 | T>I | No | 1000Genomes | |
| ENSVATH12898194 | 646 | A>T | No | 1000Genomes | |
| tmp_5_24790744_A_G | 649 | L>S | No | 1000Genomes | |
| ENSVATH14644249 | 651 | A>T | No | 1000Genomes | |
| ENSVATH14644248 | 651 | A>V | No | 1000Genomes | |
| ENSVATH07462751 | 665 | S>N | No | 1000Genomes | |
| tmp_5_24790643_C_T | 683 | D>N | No | 1000Genomes | |
| ENSVATH07462747 | 693 | T>P | No | 1000Genomes | |
| tmp_5_24790518_C_T | 695 | G>S | No | 1000Genomes | |
| ENSVATH12898189 | 697 | D>Y | No | 1000Genomes | |
| ENSVATH07462744 | 776 | V>I | No | 1000Genomes | |
| ENSVATH03462270 | 786 | F>L | No | 1000Genomes | |
| ENSVATH14644246 | 797 | E>K | No | 1000Genomes | |
| ENSVATH07462740 | 810 | D>E | No | 1000Genomes | |
| ENSVATH07462739 | 813 | N>H | No | 1000Genomes | |
| tmp_5_24790093_A_T | 813 | N>K | No | 1000Genomes | |
| ENSVATH00746942 | 817 | G>V | No | 1000Genomes | |
| tmp_5_24789966_C_G | 826 | E>Q | No | 1000Genomes | |
| tmp_5_24789915_C_T | 843 | E>K | No | 1000Genomes | |
| tmp_5_24789896_G_A | 849 | A>V | No | 1000Genomes | |
| ENSVATH12898151 | 874 | L>V | No | 1000Genomes | |
| ENSVATH07462728 | 883 | V>I | No | 1000Genomes | |
| tmp_5_24789685_G_A | 891 | A>V | No | 1000Genomes | |
| ENSVATH03462262 | 893 | N>T | No | 1000Genomes | |
| ENSVATH03462263 | 893 | N>Y | No | 1000Genomes | |
| ENSVATH14644243 | 922 | V>A | No | 1000Genomes | |
| ENSVATH07462726 | 929 | T>K | No | 1000Genomes |
No associated diseases with Q9FKF2
4 regional properties for Q9FKF2
2 GO annotations of cellular component
| Name | Definition |
|---|---|
| integral component of membrane | The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane. |
| intracellular membrane-bounded organelle | Organized structure of distinctive morphology and function, bounded by a single or double lipid bilayer membrane and occurring within the cell. Includes the nucleus, mitochondria, plastids, vacuoles, and vesicles. Excludes the plasma membrane. |
4 GO annotations of molecular function
| Name | Definition |
|---|---|
| ABC-type transporter activity | Primary active transporter characterized by two nucleotide-binding domains and two transmembrane domains. Uses the energy generated from ATP hydrolysis to drive the transport of a substance across a membrane. |
| ATP binding | Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator. |
| ATPase-coupled transmembrane transporter activity | Primary active transporter of a solute across a membrane, via the reaction: ATP + H2O = ADP + phosphate, to directly drive the transport of a substance across a membrane. The transport protein may be transiently phosphorylated (P-type transporters), or not (ABC-type transporters and other families of transporters). Primary active transport occurs up the solute's concentration gradient and is driven by a primary energy source. |
| lipid transporter activity | Enables the directed movement of lipids into, out of or within a cell, or between cells. |
1 GO annotations of biological process
| Name | Definition |
|---|---|
| lipid transport | The directed movement of lipids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Lipids are compounds soluble in an organic solvent but not, or sparingly, in an aqueous solvent. |
12 homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| Q8WWZ4 | ABCA10 | ATP-binding cassette sub-family A member 10 | Homo sapiens (Human) | PR |
| Q8N139 | ABCA6 | ATP-binding cassette sub-family A member 6 | Homo sapiens (Human) | PR |
| Q8IUA7 | ABCA9 | ATP-binding cassette sub-family A member 9 | Homo sapiens (Human) | PR |
| P78363 | ABCA4 | Retinal-specific phospholipid-transporting ATPase ABCA4 | Homo sapiens (Human) | PR |
| Q8WWZ7 | ABCA5 | Cholesterol transporter ABCA5 | Homo sapiens (Human) | PR |
| Q86UK0 | ABCA12 | Glucosylceramide transporter ABCA12 | Homo sapiens (Human) | PR |
| Q8K449 | Abca9 | ATP-binding cassette sub-family A member 9 | Mus musculus (Mouse) | PR |
| Q8K448 | Abca5 | Cholesterol transporter ABCA5 | Mus musculus (Mouse) | PR |
| Q8K442 | Abca8a | ABC-type organic anion transporter ABCA8A | Mus musculus (Mouse) | PR |
| P34358 | ced-7 | ABC transporter ced-7 | Caenorhabditis elegans | PR |
| Q84K47 | ABCA2 | ABC transporter A family member 2 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q9FLT5 | ABCA9 | ABC transporter A family member 9 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| 10 | 20 | 30 | 40 | 50 | 60 |
| MILQEGLPLL | YQQFTALFGK | NLLLSWRNKR | ATCLQIFSSF | FFILLIFCIE | EAMKASDASS |
| 70 | 80 | 90 | 100 | 110 | 120 |
| SAYKNITDPT | LLVSPPILPC | EDKFFVKLPC | YDFVWSGNNS | RRVTDIVSAI | MANNPGRPIP |
| 130 | 140 | 150 | 160 | 170 | 180 |
| TNKVQSFKEP | DEVDTWLLSH | PLQVPGALHF | VERNASVISY | GVQTNSSSES | KRGQTEDPTF |
| 190 | 200 | 210 | 220 | 230 | 240 |
| KFLVPLQVAA | EREIARSLLG | DPNFGWGLGF | KEFARPAIIT | ETTSALSVMG | PVFFLAFSMF |
| 250 | 260 | 270 | 280 | 290 | 300 |
| GFVLQLGALV | TEKELKLRQA | MTMMGVYDSA | YWLSWLTWEG | ILTLVSSLFL | VLFGMIFRFD |
| 310 | 320 | 330 | 340 | 350 | 360 |
| FFLKNSFVLV | FLLFLLFQFN | MIGLAFALSS | IISKSSSATT | VGFLVFLIGF | ITQFVSATGF |
| 370 | 380 | 390 | 400 | 410 | 420 |
| PYSSSYAVSR | RVMWSLFPPN | TFSAGLKLLL | DATSTPKSSG | ISWSNRAVCE | GGQATCVISI |
| 430 | 440 | 450 | 460 | 470 | 480 |
| NIIYQWLLGT | FLFWFVLAIY | FDNIIPNASG | VRKPIFYFLA | PGYWTGKGGN | KVEEGSIFSC |
| 490 | 500 | 510 | 520 | 530 | 540 |
| VGSVPLVEHN | TPNDKDVLEE | ETEVKQQAMD | GIADPNIAVQ | IHGLAKTYPG | TTKLGCCKCT |
| 550 | 560 | 570 | 580 | 590 | 600 |
| KTSPFHAVKG | LWMNIAKDQL | FCLLGPNGAG | KTTTISCLTG | INPVTGGDAL | IYGDSIRSSV |
| 610 | 620 | 630 | 640 | 650 | 660 |
| GISNIRKMIG | VCPQFDILWD | ALSSEQHLHL | FASIKGLPPA | SIKSTAEKLL | ADVKLTGAAK |
| 670 | 680 | 690 | 700 | 710 | 720 |
| VRAGSYSGGM | KRRLSVAVAL | IGDPKLVFLD | EPTTGMDPIT | RRHVWDIIQE | SKKGRAIILT |
| 730 | 740 | 750 | 760 | 770 | 780 |
| THSMEEADIL | SDRIGIMAKG | RLRCIGTSIR | LKSRFGTGFV | ATVSFIENKN | DNNIGVGASH |
| 790 | 800 | 810 | 820 | 830 | 840 |
| EPLKKFFKEH | LKVEPTEENK | AFMTFVIPHD | KENLLTGFFE | ELQNRESEFG | ISDIQLGLAT |
| 850 | 860 | 870 | 880 | 890 | 900 |
| LEEVFLNIAR | QAELESATAE | GNMVTLELAS | GISLEIPVGA | RFVGIPDTEN | AENPSGVMVE |
| 910 | 920 | 930 | 940 | 950 | |
| VYWQQDGSGS | MCISGHSSEM | RVPQNVPVTR | PPSPNALGHK | SLRQGVRGIV | IDL |