Q94B08

PR
Gene name
GCP1
Protein name
Germination-specific cysteine protease 1
Names
RD21A-like protease 1
Species
Arabidopsis thaliana (Mouse-ear cress)
KEGG Pathway
ath:AT4G36880
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-58 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q94B08

Entry ID Method Resolution Chain Position Source
AF-Q94B08-F1 Predicted AlphaFoldDB

No variants for Q94B08

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q94B08

No associated diseases with Q94B08

3 regional properties for Q94B08

Type Name Position InterPro Accession
domain Signal recognition particle, SRP54 subunit, GTPase domain 101 - 298 IPR000897
domain Signal recognition particle, SRP54 subunit, M-domain 329 - 430 IPR004125
domain Signal recognition particle SRP54, helical bundle 2 - 87 IPR013822

Functions

Description
EC Number
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

2 GO annotations of cellular component

Name Definition
extracellular space That part of a multicellular organism outside the cells proper, usually taken to be outside the plasma membranes, and occupied by fluid.
lysosome A small lytic vacuole that has cell cycle-independent morphology found in most animal cells and that contains a variety of hydrolases, most of which have their maximal activities in the pH range 5-6. The contained enzymes display latency if properly isolated. About 40 different lysosomal hydrolases are known and lysosomes have a great variety of morphologies and functions.

1 GO annotations of molecular function

Name Definition
cysteine-type endopeptidase activity Catalysis of the hydrolysis of internal, alpha-peptide bonds in a polypeptide chain by a mechanism in which the sulfhydryl group of a cysteine residue at the active center acts as a nucleophile.

1 GO annotations of biological process

Name Definition
proteolysis involved in protein catabolic process The hydrolysis of a peptide bond or bonds within a protein as part of the chemical reactions and pathways resulting in the breakdown of a protein by individual cells.

8 homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
P09668 CTSH Pro-cathepsin H Homo sapiens (Human) PR
O70370 Ctss Cathepsin S Mus musculus (Mouse) PR
P49935 Ctsh Pro-cathepsin H Mus musculus (Mouse) PR
P00786 Ctsh Pro-cathepsin H Rattus norvegicus (Rat) PR
P22895 P34 probable thiol protease Glycine max (Soybean) (Glycine hispida) PR
O65493 XCP1 Cysteine protease XCP1 Arabidopsis thaliana (Mouse-ear cress) PR
Q9LT77 RDL2 Probable cysteine protease RDL2 Arabidopsis thaliana (Mouse-ear cress) PR
P43296 RD19A Cysteine protease RD19A Arabidopsis thaliana (Mouse-ear cress) PR
10 20 30 40 50 60
MAPSTKVLSL LLLYVVVSLA SGDESIINDH LQLPSDGKWR TDEEVRSIYL QWSAEHGKTN
70 80 90 100 110 120
NNNNGIINDQ DKRFNIFKDN LRFIDLHNED NKNATYKLGL TKFTDLTNDE YRKLYLGART
130 140 150 160 170 180
EPARRIAKAK NVNQKYSAAV NGKEVPETVD WRQKGAVNPI KDQGTCGSCW AFSTTAAVEG
190 200 210 220 230 240
INKIVTGELI SLSEQELVDC DKSYNQGCNG GLMDYAFQFI MKNGGLNTEK DYPYRGFGGK
250 260 270 280 290 300
CNSFLKNSRV VSIDGYEDVP TKDETALKKA ISYQPVSVAI EAGGRIFQHY QSGIFTGSCG
310 320 330 340 350 360
TNLDHAVVAV GYGSENGVDY WIVRNSWGPR WGEEGYIRME RNLAASKSGK CGIAVEASYP
370
VKYSPNPVRG NTISSV