Q6AXL5

PR
Gene name
hspbap1 (si:dkey-25l23.5, zgc:100975)
Protein name
HSPB1-associated protein 1 homolog
Names
Species
Danio rerio (Zebrafish) (Brachydanio rerio)
KEGG Pathway
dre:445320
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

249-441 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q6AXL5

Entry ID Method Resolution Chain Position Source
AF-Q6AXL5-F1 Predicted AlphaFoldDB

No variants for Q6AXL5

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q6AXL5

No associated diseases with Q6AXL5

2 regional properties for Q6AXL5

Type Name Position InterPro Accession
domain JmjC domain 102 - 266 IPR003347
domain Cupin-like domain 8 16 - 255 IPR041667

Functions

Description
EC Number
Subcellular Localization
  • Cytoplasm
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.

1 GO annotations of molecular function

Name Definition
2-oxoglutarate-dependent dioxygenase activity Catalysis of the reaction: A + 2-oxoglutarate + O2 = B + succinate + CO2. This is an oxidation-reduction (redox) reaction in which hydrogen or electrons are transferred from 2-oxoglutarate and one other donor, and one atom of oxygen is incorporated into each donor.

No GO annotations of biological process

Name Definition
No GO annotations for biological process

9 homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
Q58CU3 HSPBAP1 HSPB1-associated protein 1 Bos taurus (Bovine) PR
E1C7T6 TYW5 tRNA wybutosine-synthesizing protein 5 Gallus gallus (Chicken) PR
Q96EW2 HSPBAP1 HSPB1-associated protein 1 Homo sapiens (Human) PR
Q8BK58 Hspbap1 HSPB1-associated protein 1 Mus musculus (Mouse) PR
Q5BKC6 Hspbap1 HSPB1-associated protein 1 Rattus norvegicus (Rat) PR
Q8RWR1 JMJ30 Lysine-specific demethylase JMJ30 Arabidopsis thaliana (Mouse-ear cress) PR
B2GUS6 kdm8 Lysine-specific demethylase 8 Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) PR
Q08BV2 tyw5 tRNA wybutosine-synthesizing protein 5 Danio rerio (Zebrafish) (Brachydanio rerio) PR
A8E534 kdm8 Lysine-specific demethylase 8 Danio rerio (Zebrafish) (Brachydanio rerio) PR
10 20 30 40 50 60
MSSKPFTPEE ARRIVQVLQK PAVFLNMTTD WPALHWTVEH LSACLTKRIR FRVGKRSEDM
70 80 90 100 110 120
APLFETECSY VEATIKEFLS WTANDGEPLV GPFLDYHCKE FWAYADYKYI AQLFQDKPAM
130 140 150 160 170 180
FQDVVWSDFG FPGRDGRDST LWIGTQCANT PCHLDSYGCN LVFQIQGRKR WHLFPPDDTA
190 200 210 220 230 240
CLYPTRVPYE ESSVFSHVNV IRPDLKKFPA YGRARLYTVT LQPGQVLFVP RHWWHYVESV
250 260 270 280 290 300
DPVTVSVNSW IEMDMDDEAR VAEALTKTIV CAVKSSPSLD NSDQWLNPTE DGVSSHDENM
310 320 330 340 350 360
QYLNLAVKVC MNKKRDDIED QPKAEAVKRD FSGVLKSPAS PPSLVSFGPH LIPVHLTEKP
370 380 390 400 410 420
QCSSTKDSCC FSCTDSPQCQ ITTKDQDKLR SDNKLGQRSG QSVLQDTENP GGSGEMHIST
430 440
NDVLECLVHP DVIALVTRLI MCRQRELHS