Q5BKC6

PR
Gene name
Hspbap1 (Pass1)
Protein name
HSPB1-associated protein 1
Names
27 kDa heat shock protein-associated protein 1, Protein associated with small stress protein 1
Species
Rattus norvegicus (Rat)
KEGG Pathway
rno:171460
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-60 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q5BKC6

Entry ID Method Resolution Chain Position Source
AF-Q5BKC6-F1 Predicted AlphaFoldDB

2 variants for Q5BKC6

Variant ID(s) Position Change Description Diseaes Association Provenance
rs197338690 24 R>C No EVA
rs13452189 371 D>E No EVA

No associated diseases with Q5BKC6

2 regional properties for Q5BKC6

Type Name Position InterPro Accession
domain JmjC domain 124 - 288 IPR003347
domain Cupin-like domain 8 35 - 273 IPR041667

Functions

Description
EC Number
Subcellular Localization
  • Cytoplasm
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.

1 GO annotations of molecular function

Name Definition
2-oxoglutarate-dependent dioxygenase activity Catalysis of the reaction: A + 2-oxoglutarate + O2 = B + succinate + CO2. This is an oxidation-reduction (redox) reaction in which hydrogen or electrons are transferred from 2-oxoglutarate and one other donor, and one atom of oxygen is incorporated into each donor.

No GO annotations of biological process

Name Definition
No GO annotations for biological process

9 homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
Q58CU3 HSPBAP1 HSPB1-associated protein 1 Bos taurus (Bovine) PR
E1C7T6 TYW5 tRNA wybutosine-synthesizing protein 5 Gallus gallus (Chicken) PR
Q96EW2 HSPBAP1 HSPB1-associated protein 1 Homo sapiens (Human) PR
Q8BK58 Hspbap1 HSPB1-associated protein 1 Mus musculus (Mouse) PR
Q8RWR1 JMJ30 Lysine-specific demethylase JMJ30 Arabidopsis thaliana (Mouse-ear cress) PR
B2GUS6 kdm8 Lysine-specific demethylase 8 Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) PR
Q08BV2 tyw5 tRNA wybutosine-synthesizing protein 5 Danio rerio (Zebrafish) (Brachydanio rerio) PR
A8E534 kdm8 Lysine-specific demethylase 8 Danio rerio (Zebrafish) (Brachydanio rerio) PR
Q6AXL5 hspbap1 HSPB1-associated protein 1 homolog Danio rerio (Zebrafish) (Brachydanio rerio) PR
10 20 30 40 50 60
MEAGCEGSSP QTLGERTMGE EGERVKPFTP EKAKEVIMSL QQPAIFCNMV FDWPSRHWTA
70 80 90 100 110 120
KHLSKVLEGK QIRFRMGLRS TGTVPQFETE CSYVDATLEE FLAWNCDQSR ISGPFKKYDH
130 140 150 160 170 180
SKFWAYADYK YFVTLFEDKT DVFQEVMWSD FGFPGRNGQE STLWIGSLGA HTPCHLDSYG
190 200 210 220 230 240
CNLVFQVQGR KRWHLFPPED TPFLYPTRIP YEESSVFSKI NVVNPDLKRF PQFQKARRHM
250 260 270 280 290 300
VTLSPGQVLF VPRHWWHYVE SLDPVTVSIN SWIELEEDHL ARVEEAVTRM LVCTLKTAED
310 320 330 340 350 360
PHHPRTWLNP TEVEETSHEV NSCYLNSAVC AFFDHCERAK EVEMQAPRAN GEEPGVQEHM
370 380 390 400 410 420
EVEQARDPSS DVGAGKQEAA SPFGPDLVPV TPASEERGGA LEGDSQECTS RNGEHCAELP
430 440 450 460 470
CARRQQASKG ARAEAGQSAP RYPVAPSRVF VSTDDLLDCL VNPQVTRMVA QLLIQGKSL