Q67UF5
Gene name |
PDIL2-3 (PDIL5-1) |
Protein name |
Protein disulfide isomerase-like 2-3 |
Names |
OsPDIL2-3, Protein disulfide isomerase-like 5-1, OsPDIL5-1 |
Species |
Oryza sativa subsp japonica (Rice) |
KEGG Pathway |
osa:4347226 |
EC number |
5.3.4.1: Transposing S-S bonds |
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q67UF5
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q67UF5-F1 | Predicted | AlphaFoldDB |
No variants for Q67UF5
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for Q67UF5 | |||||
No associated diseases with Q67UF5
6 regional properties for Q67UF5
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| domain | Protein disulfide-isomerase, thioredoxin-like domain | 35 - 132 | IPR005788-1 |
| domain | Protein disulfide-isomerase, thioredoxin-like domain | 170 - 270 | IPR005788-2 |
| domain | Thioredoxin domain | 12 - 139 | IPR013766-1 |
| domain | Thioredoxin domain | 159 - 276 | IPR013766-2 |
| conserved_site | Thioredoxin, conserved site | 51 - 69 | IPR017937-1 |
| conserved_site | Thioredoxin, conserved site | 187 - 205 | IPR017937-2 |
Functions
| Description | ||
|---|---|---|
| EC Number | 5.3.4.1 | Transposing S-S bonds |
| Subcellular Localization |
|
|
| PANTHER Family | ||
| PANTHER Subfamily | ||
| PANTHER Protein Class | ||
| PANTHER Pathway Category | No pathway information available | |
1 GO annotations of cellular component
| Name | Definition |
|---|---|
| endoplasmic reticulum lumen | The volume enclosed by the membranes of the endoplasmic reticulum. |
2 GO annotations of molecular function
| Name | Definition |
|---|---|
| protein disulfide isomerase activity | Catalysis of the rearrangement of both intrachain and interchain disulfide bonds in proteins. |
| protein-disulfide reductase activity | Catalysis of the reaction: a protein with reduced sulfide groups = a protein with oxidized disulfide bonds. |
1 GO annotations of biological process
| Name | Definition |
|---|---|
| response to endoplasmic reticulum stress | Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stress acting at the endoplasmic reticulum. ER stress usually results from the accumulation of unfolded or misfolded proteins in the ER lumen. |
12 homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| Q12404 | MPD1 | Protein disulfide-isomerase MPD1 | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) | PR |
| Q2KIL5 | PDIA5 | Protein disulfide-isomerase A5 | Bos taurus (Bovine) | PR |
| Q8N807 | PDILT | Protein disulfide-isomerase-like protein of the testis | Homo sapiens (Human) | PR |
| Q15084 | PDIA6 | Protein disulfide-isomerase A6 | Homo sapiens (Human) | PR |
| Q921X9 | Pdia5 | Protein disulfide-isomerase A5 | Mus musculus (Mouse) | PR |
| Q922R8 | Pdia6 | Protein disulfide-isomerase A6 | Mus musculus (Mouse) | PR |
| Q5I0H9 | Pdia5 | Protein disulfide-isomerase A5 | Rattus norvegicus (Rat) | PR |
| Q63081 | Pdia6 | Protein disulfide-isomerase A6 | Rattus norvegicus (Rat) | PR |
| Q10N04 | PDIL5-1 | Protein disulfide isomerase-like 5-1 | Oryza sativa subsp japonica (Rice) | PR |
| Q8GYD1 | PDIL5-1 | Protein disulfide-isomerase 5-1 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| O48773 | PDIL2-3 | Protein disulfide-isomerase 2-3 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q9MAU6 | PDIL2-2 | Protein disulfide-isomerase like 2-2 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| 10 | 20 | 30 | 40 | 50 | 60 |
| MRPAVAAALL | LVAAAVAASP | VSALYSAGSP | VLQFNPNNFK | SKVLNSNGVV | LVEFFAPWCG |
| 70 | 80 | 90 | 100 | 110 | 120 |
| HCQQLTPIWE | KAAGVLKGVA | TVAALDADAH | KELAQEYGIR | GFPTIKVFVP | GKPPVDYQGA |
| 130 | 140 | 150 | 160 | 170 | 180 |
| RDVKPIVEFA | LSQVKALLRD | RLNGKTSAGS | GGKKSGGSSE | KTEPSASIEL | NSQNFDKLVT |
| 190 | 200 | 210 | 220 | 230 | 240 |
| KSKDLWIVEF | FAPWCGHCKK | LAPEWKKAAK | NLKGQVKLGH | VDCDAEKSLM | SKYKVEGFPT |
| 250 | 260 | 270 | 280 | 290 | 300 |
| ILVFGADKES | PFPYQGARVA | SAIESFALEQ | LEANAAPPEV | SELTGPDAME | EKCASAAICF |
| 310 | 320 | 330 | 340 | 350 | 360 |
| VSFLPDILDS | KAEGRNKYLE | LLLSVAEKFK | KSPYSFVWTA | AGKQADLEKQ | VGVGGYGYPA |
| 370 | 380 | 390 | 400 | 410 | 420 |
| MVALNVKKGA | YAPLRSAFQL | DEITEFVKEA | GRGGKGNLPL | DGTPTIVQSE | PWDGKDGEVI |
| 430 | 440 | ||||
| EEDEFSLEEL | MADNSPVNDE | L |