Q0P4Q4
Gene name |
frmd3 |
Protein name |
FERM domain-containing protein 3 |
Names |
|
Species |
Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) |
KEGG Pathway |
xtr:779965 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q0P4Q4
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q0P4Q4-F1 | Predicted | AlphaFoldDB |
No variants for Q0P4Q4
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for Q0P4Q4 | |||||
No associated diseases with Q0P4Q4
1 regional properties for Q0P4Q4
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| domain | ABT1/ESF2, RNA recognition motif | 146 - 243 | IPR034353 |
2 GO annotations of cellular component
| Name | Definition |
|---|---|
| cytoskeleton | A cellular structure that forms the internal framework of eukaryotic and prokaryotic cells. The cytoskeleton includes intermediate filaments, microfilaments, microtubules, the microtrabecular lattice, and other structures characterized by a polymeric filamentous nature and long-range order within the cell. The various elements of the cytoskeleton not only serve in the maintenance of cellular shape but also have roles in other cellular functions, including cellular movement, cell division, endocytosis, and movement of organelles. |
| integral component of membrane | The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane. |
1 GO annotations of molecular function
| Name | Definition |
|---|---|
| cytoskeletal protein binding | Binding to a protein component of a cytoskeleton (actin, microtubule, or intermediate filament cytoskeleton). |
1 GO annotations of biological process
| Name | Definition |
|---|---|
| actomyosin structure organization | A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures containing both actin and myosin or paramyosin. The myosin may be organized into filaments. |
10 homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| Q58CU2 | EPB41L5 | Band 4.1-like protein 5 | Bos taurus (Bovine) | PR |
| Q9HCS5 | EPB41L4A | Band 4.1-like protein 4A | Homo sapiens (Human) | PR |
| Q9HCM4 | EPB41L5 | Band 4.1-like protein 5 | Homo sapiens (Human) | PR |
| Q7Z6J6 | FRMD5 | FERM domain-containing protein 5 | Homo sapiens (Human) | PR |
| A2A2Y4 | FRMD3 | FERM domain-containing protein 3 | Homo sapiens (Human) | PR |
| P52963 | Epb41l4a | Band 4.1-like protein 4A | Mus musculus (Mouse) | PR |
| Q8BGS1 | Epb41l5 | Band 4.1-like protein 5 | Mus musculus (Mouse) | PR |
| Q6P5H6 | Frmd5 | FERM domain-containing protein 5 | Mus musculus (Mouse) | PR |
| Q8BHD4 | Frmd3 | FERM domain-containing protein 3 | Mus musculus (Mouse) | PR |
| O57457 | epb41l4a | Band 4.1-like protein 4 | Danio rerio (Zebrafish) (Brachydanio rerio) | PR |
| 10 | 20 | 30 | 40 | 50 | 60 |
| MFGCQCPRKK | KGTMTMMRLR | TASLRSLNLD | MRCTIRLLDD | TEISFNIQRD | TKGQFLLDYI |
| 70 | 80 | 90 | 100 | 110 | 120 |
| CNHYNLLEKD | YFGIRFVDPE | KQRHWLDPSK | PVAKQMKSHP | PYTMCFRVKF | YPHEPLKIKE |
| 130 | 140 | 150 | 160 | 170 | 180 |
| ELTRYLLYLQ | IKRDIFHGRL | LCCFADAAFL | GACIVQAEIG | DYDPDEHPDN | YICDFKIFPK |
| 190 | 200 | 210 | 220 | 230 | 240 |
| QSQKLERKIV | EIHKNELRGQ | SPSVSEFNLL | LKAHSLETYG | VDPHPCKDST | GTTTFLGYTA |
| 250 | 260 | 270 | 280 | 290 | 300 |
| AGFVVFQGNK | RIHLIKWPDI | CKMKFDGKTF | HVVVMQKEKK | NILTYHTSTP | AACKHLWKCG |
| 310 | 320 | 330 | 340 | 350 | 360 |
| VENQAFYKYA | KSSQVKTVTS | SNIFFKGSRF | RYCGKVAKEV | VEASSKIQRD | PPEVHRSLIP |
| 370 | 380 | 390 | 400 | 410 | 420 |
| HSRSSYSLNK | QLIINMEPLQ | PLIPSPNEEE | EEEEEENQID | EGILLLQQSE | ASSAPVLGNS |
| 430 | 440 | 450 | 460 | 470 | 480 |
| PARGLETTAD | VTHDEEESIR | EEPLTISEQV | YNPSASLLPT | PVDEGIDMLF | NSPLRAEREK |
| 490 | 500 | 510 | 520 | 530 | 540 |
| DDTDSFEDLE | ADEHAFLIAE | EEEMKEARKA | LSWSYNFIMG | NMQLNAFLKS | FSKLLLAAIG |
| 550 | 560 | 570 | 580 | 590 | |
| LLMVVLPLLL | ILLESDIDVS | FLREIRLTPE | FEQFHHEYYC | PFRKWVACKL | SAALNLFGST |