Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

Autoinhibited structure

Activated structure

1 structures for P34430

Entry ID Method Resolution Chain Position Source
AF-P34430-F1 Predicted AlphaFoldDB

No variants for P34430

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for P34430

No associated diseases with P34430

2 regional properties for P34430

Type Name Position InterPro Accession
domain Calcineurin-like phosphoesterase domain, ApaH type 32 - 119 IPR004843
domain Serine/threonine-specific protein phosphatase/bis(5-nucleosyl)-tetraphosphatase 4 - 222 IPR006186

Functions

Description
EC Number
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

2 GO annotations of cellular component

Name Definition
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
nucleus A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.

1 GO annotations of molecular function

Name Definition
protein serine/threonine phosphatase activity Catalysis of the reaction: protein serine phosphate + H2O = protein serine + phosphate, and protein threonine phosphate + H2O = protein threonine + phosphate.

No GO annotations of biological process

Name Definition
No GO annotations for biological process

7 homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
P62136 PPP1CA Serine/threonine-protein phosphatase PP1-alpha catalytic subunit Homo sapiens (Human) PR
P62140 PPP1CB Serine/threonine-protein phosphatase PP1-beta catalytic subunit Homo sapiens (Human) PR
P62141 Ppp1cb Serine/threonine-protein phosphatase PP1-beta catalytic subunit Mus musculus (Mouse) PR
P62137 Ppp1ca Serine/threonine-protein phosphatase PP1-alpha catalytic subunit Mus musculus (Mouse) PR
P62142 Ppp1cb Serine/threonine-protein phosphatase PP1-beta catalytic subunit Rattus norvegicus (Rat) PR
P48459 C23G10.1 Serine/threonine-protein phosphatase C23G10.1 Caenorhabditis elegans PR
O82733 TOPP7 Serine/threonine-protein phosphatase PP1 isozyme 7 Arabidopsis thaliana (Mouse-ear cress) PR
10 20 30 40 50 60
MRTYSKTELF CLLDMVIELF KKEKTLAEIS PPVTIVGDIH GQFEDLVRLL NTRNSSENAK
70 80 90 100 110 120
SKPIYGFSTK KWVFLGDYVD RGYKSLDCIC LVFSLKICFP KQYILLRGNH ETRAINFRYG
130 140 150 160 170 180
FRVCSVVVLK IPAKPSFIRN NKRGLSVCFN EAAVNETCRL LNISLIVRGH QMMPAGFKFF
190 200 210 220 230 240
ADRKLCTIFS APRYMNEIDN SGAVMKVASN GKISISIMKN PNFAMKMFLL QMKSHNSLDH
250
RNMRLSKNSN NLPS