Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for P34430
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-P34430-F1 | Predicted | AlphaFoldDB |
No variants for P34430
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for P34430 | |||||
No associated diseases with P34430
2 GO annotations of cellular component
| Name | Definition |
|---|---|
| cytoplasm | The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures. |
| nucleus | A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent. |
1 GO annotations of molecular function
| Name | Definition |
|---|---|
| protein serine/threonine phosphatase activity | Catalysis of the reaction: protein serine phosphate + H2O = protein serine + phosphate, and protein threonine phosphate + H2O = protein threonine + phosphate. |
No GO annotations of biological process
| Name | Definition |
|---|---|
| No GO annotations for biological process |
7 homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| P62136 | PPP1CA | Serine/threonine-protein phosphatase PP1-alpha catalytic subunit | Homo sapiens (Human) | PR |
| P62140 | PPP1CB | Serine/threonine-protein phosphatase PP1-beta catalytic subunit | Homo sapiens (Human) | PR |
| P62141 | Ppp1cb | Serine/threonine-protein phosphatase PP1-beta catalytic subunit | Mus musculus (Mouse) | PR |
| P62137 | Ppp1ca | Serine/threonine-protein phosphatase PP1-alpha catalytic subunit | Mus musculus (Mouse) | PR |
| P62142 | Ppp1cb | Serine/threonine-protein phosphatase PP1-beta catalytic subunit | Rattus norvegicus (Rat) | PR |
| P48459 | C23G10.1 | Serine/threonine-protein phosphatase C23G10.1 | Caenorhabditis elegans | PR |
| O82733 | TOPP7 | Serine/threonine-protein phosphatase PP1 isozyme 7 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| 10 | 20 | 30 | 40 | 50 | 60 |
| MRTYSKTELF | CLLDMVIELF | KKEKTLAEIS | PPVTIVGDIH | GQFEDLVRLL | NTRNSSENAK |
| 70 | 80 | 90 | 100 | 110 | 120 |
| SKPIYGFSTK | KWVFLGDYVD | RGYKSLDCIC | LVFSLKICFP | KQYILLRGNH | ETRAINFRYG |
| 130 | 140 | 150 | 160 | 170 | 180 |
| FRVCSVVVLK | IPAKPSFIRN | NKRGLSVCFN | EAAVNETCRL | LNISLIVRGH | QMMPAGFKFF |
| 190 | 200 | 210 | 220 | 230 | 240 |
| ADRKLCTIFS | APRYMNEIDN | SGAVMKVASN | GKISISIMKN | PNFAMKMFLL | QMKSHNSLDH |
| 250 | |||||
| RNMRLSKNSN | NLPS |