A1L1W9
Gene name |
slc16a10 (si:ch211-241j12.1, zgc:158478) |
Protein name |
Monocarboxylate transporter 10 |
Names |
MCT 10, Solute carrier family 16 member 10 |
Species |
Danio rerio (Zebrafish) (Brachydanio rerio) |
KEGG Pathway |
dre:566499 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for A1L1W9
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-A1L1W9-F1 | Predicted | AlphaFoldDB |
No variants for A1L1W9
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for A1L1W9 | |||||
No associated diseases with A1L1W9
No regional properties for A1L1W9
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| No domain, repeats, and functional sites for A1L1W9 | |||
3 GO annotations of cellular component
| Name | Definition |
|---|---|
| basolateral plasma membrane | The region of the plasma membrane that includes the basal end and sides of the cell. Often used in reference to animal polarized epithelial membranes, where the basal membrane is the part attached to the extracellular matrix, or in plant cells, where the basal membrane is defined with respect to the zygotic axis. |
| integral component of membrane | The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane. |
| integral component of plasma membrane | The component of the plasma membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane. |
5 GO annotations of molecular function
| Name | Definition |
|---|---|
| aromatic amino acid transmembrane transporter activity | Enables the transfer of aromatic amino acids from one side of a membrane to the other. Aromatic amino acids have an aromatic ring. |
| L-phenylalanine transmembrane transporter activity | Enables the transfer of L-phenylalanine from one side of a membrane to the other. L-phenylalanine is 2-amino-3-phenylpropanoic acid. |
| L-tryptophan transmembrane transporter activity | Enables the transfer of L-tryptophan from one side of a membrane to the other. Tryptophan is 2-amino-3-(1H-indol-3-yl)propanoic acid. |
| L-tyrosine transmembrane transporter activity | Enables the transfer of L-tyrosine from one side of a membrane to the other. L-tyrosine is 2-amino-3-(4-hydroxyphenyl)propanoic acid. |
| thyroid hormone transmembrane transporter activity | Enables the transfer of thyroid hormones from one side of a membrane to the other. Thyroid hormone are any of the compounds secreted by the thyroid gland, largely thyroxine and triiodothyronine. |
2 GO annotations of biological process
| Name | Definition |
|---|---|
| aromatic amino acid transport | The directed movement of aromatic amino acids, amino acids with aromatic ring, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. |
| thyroid hormone transport | The directed movement of thyroid hormone into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. |
8 homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| P57788 | SLC16A3 | Monocarboxylate transporter 4 | Gallus gallus (Chicken) | PR |
| P36021 | SLC16A2 | Monocarboxylate transporter 8 | Homo sapiens (Human) | PR |
| Q8TF71 | SLC16A10 | Monocarboxylate transporter 10 | Homo sapiens (Human) | PR |
| Q8R0M8 | Slc16a4 | Monocarboxylate transporter 5 | Mus musculus (Mouse) | PR |
| O70324 | Slc16a2 | Monocarboxylate transporter 8 | Mus musculus (Mouse) | PR |
| O35308 | Slc16a8 | Monocarboxylate transporter 3 | Mus musculus (Mouse) | PR |
| P57787 | Slc16a3 | Monocarboxylate transporter 4 | Mus musculus (Mouse) | PR |
| O70461 | Slc16a8 | Monocarboxylate transporter 3 | Rattus norvegicus (Rat) | PR |
| 10 | 20 | 30 | 40 | 50 | 60 |
| MTEPEPTLEQ | EPTPEPEPTQ | EPTPEPTPEP | EPTQEPESEP | ELELKQENGC | TKASEQKSPE |
| 70 | 80 | 90 | 100 | 110 | 120 |
| EFEPPEGGWG | WVVMLASMWC | NGSVFGIQNA | FGIMFVYLLN | EFGSEHDADL | RFKTAWVGSL |
| 130 | 140 | 150 | 160 | 170 | 180 |
| SMGMIFFCSP | IVSVFTDLLG | CRITAVGGAA | VGCVGLLASS | FVTSLGPMYF | TYGIVFACGC |
| 190 | 200 | 210 | 220 | 230 | 240 |
| SFAYQPSLVI | LGHYFKRRLG | LVNGIVTAGS | SVFTITLPYM | LSGLLKSVGL | YHTLRVLAIF |
| 250 | 260 | 270 | 280 | 290 | 300 |
| MFILMLAGLT | YKPLLPKPVS | SSKPGSRCPP | LSRIFNVNIW | KSLGYRIWAF | GIPAALYGYF |
| 310 | 320 | 330 | 340 | 350 | 360 |
| VPYVHLMTHV | EERFGPEANK | EVLLACIGIT | SGVGRLIFGR | VADYVPGVNK | VFLQVSSFMV |
| 370 | 380 | 390 | 400 | 410 | 420 |
| IGVMSMMIPL | CHVFGGLIAV | CLLMGLFDGC | FICIMAPIAF | ELVGSQNVSQ | AIGFLLGMMS |
| 430 | 440 | 450 | 460 | 470 | 480 |
| IPMTVGPPIA | GFLRDRLGSY | DVAFYLAGIP | PLIGGAVLCA | IPWVEARRKR | REAANTAENT |
| 490 | 500 | ||||
| EKMLESRSPP | LEDTVCRTEE | PESVI |