Q9SJ22
PR
Gene name |
CESA9 (CESA09, At2g21770, F7D8.9) |
Protein name |
Probable cellulose synthase A catalytic subunit 9 [UDP-forming] |
Names |
AtCesA9 |
Species |
Arabidopsis thaliana (Mouse-ear cress) |
KEGG Pathway |
ath:AT2G21770 |
EC number |
2.4.1.12: Hexosyltransferases |
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q9SJ22
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q9SJ22-F1 | Predicted | AlphaFoldDB |
84 variants for Q9SJ22
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| tmp_2_9284842_C_A | 2 | N>K | No | 1000Genomes | |
| ENSVATH13318464 | 19 | L>F | No | 1000Genomes | |
| ENSVATH01860294 | 31 | A>V | No | 1000Genomes | |
| tmp_2_9285404_A_T | 47 | E>V | No | 1000Genomes | |
| ENSVATH01860295 | 55 | F>L | No | 1000Genomes | |
| ENSVATH01860296 | 85 | G>R | No | 1000Genomes | |
| ENSVATH05550454 | 86 | T>A | No | 1000Genomes | |
| ENSVATH13318480 | 87 | R>P | No | 1000Genomes | |
| ENSVATH01860301 | 101 | E>D | No | 1000Genomes | |
| tmp_2_9285671_C_A | 111 | H>N | No | 1000Genomes | |
| tmp_2_9285692_C_A | 118 | P>T | No | 1000Genomes | |
| ENSVATH01860303 | 122 | T>A | No | 1000Genomes | |
| ENSVATH05550459 | 123 | E>D | No | 1000Genomes | |
| ENSVATH00241647 | 124 | A>P | No | 1000Genomes | |
| ENSVATH00241649 | 128 | Y>D | No | 1000Genomes | |
| ENSVATH05550461 | 162 | S>F | No | 1000Genomes | |
| ENSVATH13318499 | 166 | S>L | No | 1000Genomes | |
| ENSVATH05550462 | 170 | A>V | No | 1000Genomes | |
| ENSVATH00241651 | 182 | R>K | No | 1000Genomes | |
| ENSVATH13318500 | 194 | S>P | No | 1000Genomes | |
| tmp_2_9286161_A_C | 217 | K>N | No | 1000Genomes | |
| ENSVATH00241653 | 220 | M>T | No | 1000Genomes | |
| tmp_2_9286200_G_C | 230 | K>N | No | 1000Genomes | |
| ENSVATH13318502 | 232 | Q>R | No | 1000Genomes | |
| ENSVATH00241654 | 256 | G>E | No | 1000Genomes | |
| tmp_2_9286370_G_A | 259 | M>I | No | 1000Genomes | |
| tmp_2_9286458_C_T | 289 | L>F | No | 1000Genomes | |
| ENSVATH13318504 | 351 | K>R | No | 1000Genomes | |
| ENSVATH00241655 | 353 | G>R | No | 1000Genomes | |
| ENSVATH01860317 | 359 | A>V | No | 1000Genomes | |
| ENSVATH05550466 | 396 | A>S | No | 1000Genomes | |
| ENSVATH13318516 | 405 | A>S | No | 1000Genomes | |
| ENSVATH05550467 | 444 | M>I | No | 1000Genomes | |
| ENSVATH00241656 | 452 | D>V | No | 1000Genomes | |
| ENSVATH14528970 | 465 | D>V | No | 1000Genomes | |
| ENSVATH01860321 | 480 | S>A | No | 1000Genomes | |
| tmp_2_9287197_G_A | 502 | R>Q | No | 1000Genomes | |
| tmp_2_9287324_G_T | 519 | D>Y | No | 1000Genomes | |
| ENSVATH00241657 | 527 | R>S | No | 1000Genomes | |
| tmp_2_9287520_T_C | 557 | V>A | No | 1000Genomes | |
| ENSVATH01860326 | 561 | A>S | No | 1000Genomes | |
| ENSVATH01860327 | 575 | N>Y | No | 1000Genomes | |
| ENSVATH05550476 | 582 | A>S | No | 1000Genomes | |
| tmp_2_9287678_C_T | 610 | H>Y | No | 1000Genomes | |
| ENSVATH13318537 | 652 | D>Y | No | 1000Genomes | |
| ENSVATH01860333 | 658 | Q>K | No | 1000Genomes | |
| tmp_2_9287961_G_A | 676 | G>S | No | 1000Genomes | |
| ENSVATH05550483 | 679 | K>N | No | 1000Genomes | |
| ENSVATH01860335 | 685 | V>A | No | 1000Genomes | |
| tmp_2_9287998_A_T | 688 | N>I | No | 1000Genomes | |
| ENSVATH05550484 | 689 | Q>K | No | 1000Genomes | |
| tmp_2_9288005_A_C | 690 | R>S | No | 1000Genomes | |
| ENSVATH01860336 | 694 | K>Q | No | 1000Genomes | |
| ENSVATH01860337 | 694 | K>R | No | 1000Genomes | |
| ENSVATH01860340 | 710 | L>I | No | 1000Genomes | |
| ENSVATH01860343 | 713 | T>K | No | 1000Genomes | |
| tmp_2_9288169_A_G | 714 | N>S | No | 1000Genomes | |
| ENSVATH05550486 | 717 | N>Y | No | 1000Genomes | |
| ENSVATH00241661 | 736 | L>F | No | 1000Genomes | |
| tmp_2_9288279_G_A | 751 | V>M | No | 1000Genomes | |
| tmp_2_9288284_C_A | 752 | N>K | No | 1000Genomes | |
| ENSVATH13318539 | 755 | S>C | No | 1000Genomes | |
| tmp_2_9288345_G_C | 773 | E>Q | No | 1000Genomes | |
| tmp_2_9288359_G_C | 777 | E>D | No | 1000Genomes | |
| tmp_2_9288445_T_C | 778 | I>T | No | 1000Genomes | |
| ENSVATH14528972 | 794 | K>N | No | 1000Genomes | |
| ENSVATH05550491 | 797 | C>Y | No | 1000Genomes | |
| tmp_2_9288540_G_A | 810 | A>T | No | 1000Genomes | |
| tmp_2_9288597_C_A | 829 | R>S | No | 1000Genomes | |
| ENSVATH14528973 | 833 | G>D | No | 1000Genomes | |
| tmp_2_9288634_G_T | 841 | R>M | No | 1000Genomes | |
| tmp_2_9288666_G_A | 852 | G>S | No | 1000Genomes | |
| ENSVATH14528974 | 860 | S>P | No | 1000Genomes | |
| tmp_2_9288711_T_C | 867 | Y>H | No | 1000Genomes | |
| ENSVATH13318542 | 884 | C>Y | No | 1000Genomes | |
| tmp_2_9288959_G_T | 911 | A>S | No | 1000Genomes | |
| tmp_2_9288977_G_A | 917 | E>K | No | 1000Genomes | |
| ENSVATH00241664 | 923 | I>V | No | 1000Genomes | |
| tmp_2_9289044_G_A | 939 | G>E | No | 1000Genomes | |
| ENSVATH00241665 | 959 | S>N | No | 1000Genomes | |
| tmp_2_9289259_G_A | 1011 | G>R | No | 1000Genomes | |
| ENSVATH13318576 | 1034 | P>Q | No | 1000Genomes | |
| tmp_2_9289412_A_G | 1062 | T>A | No | 1000Genomes | |
| ENSVATH14528996 | 1076 | G>E | No | 1000Genomes |
No associated diseases with Q9SJ22
9 regional properties for Q9SJ22
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| domain | ABC transporter-like, ATP-binding domain | 423 - 646 | IPR003439-1 |
| domain | ABC transporter-like, ATP-binding domain | 1212 - 1445 | IPR003439-2 |
| domain | AAA+ ATPase domain | 450 - 639 | IPR003593-1 |
| domain | AAA+ ATPase domain | 1238 - 1420 | IPR003593-2 |
| domain | ABC transporter type 1, transmembrane domain | 82 - 349 | IPR011527-1 |
| domain | ABC transporter type 1, transmembrane domain | 860 - 1159 | IPR011527-2 |
| conserved_site | ABC transporter-like, conserved site | 548 - 562 | IPR017871 |
| domain | CFTR regulator domain | 639 - 849 | IPR025837 |
| domain | Cystic fibrosis transmembrane conductance regulator, ATP-binding cassette domain 1 | 389 - 670 | IPR047082 |
Functions
| Description | ||
|---|---|---|
| EC Number | 2.4.1.12 | Hexosyltransferases |
| Subcellular Localization |
|
|
| PANTHER Family | ||
| PANTHER Subfamily | ||
| PANTHER Protein Class | ||
| PANTHER Pathway Category | No pathway information available | |
2 GO annotations of cellular component
| Name | Definition |
|---|---|
| integral component of membrane | The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane. |
| plasma membrane | The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins. |
3 GO annotations of molecular function
| Name | Definition |
|---|---|
| cellulose synthase (UDP-forming) activity | Catalysis of the reaction: UDP-glucose + ((1,4)-beta-D-glucosyl)(n) = UDP + ((1,4)-beta-D-glucosyl)(n+1). |
| cellulose synthase activity | Catalysis of the reaction: nucleoside-disphosphate-glucose + ((1,4)-beta-D-glucosyl)(n) = nucleoside-disphosphate + ((1,4)-beta-D-glucosyl)(n+1). |
| metal ion binding | Binding to a metal ion. |
4 GO annotations of biological process
| Name | Definition |
|---|---|
| cell wall organization | A process that results in the assembly, arrangement of constituent parts, or disassembly of the cell wall, the rigid or semi-rigid envelope lying outside the cell membrane of plant, fungal and most prokaryotic cells, maintaining their shape and protecting them from osmotic lysis. |
| cellulose biosynthetic process | The chemical reactions and pathways resulting in the formation of cellulose, a linear beta1-4 glucan of molecular mass 50-400 kDa with the pyranose units in the -4C1 conformation. |
| plant-type primary cell wall biogenesis | A cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of cellulose and pectin-containing cell walls that form adjacent to the middle lamella following cell division and during cell expansion. An example of this is found in Arabidopsis thaliana. |
| seed coat development | The process whose specific outcome is the progression of the seed coat over time, from its formation to the mature structure. |
8 homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| Q69V23 | CESA3 | Probable cellulose synthase A catalytic subunit 3 [UDP-forming] | Oryza sativa subsp japonica (Rice) | PR |
| Q6YVM4 | CESA6 | Probable cellulose synthase A catalytic subunit 6 [UDP-forming] | Oryza sativa subsp japonica (Rice) | PR |
| Q851L8 | CESA5 | Probable cellulose synthase A catalytic subunit 5 [UDP-forming] | Oryza sativa subsp japonica (Rice) | PR |
| O48947 | CESA2 | Cellulose synthase A catalytic subunit 2 [UDP-forming] | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q94JQ6 | CESA6 | Cellulose synthase A catalytic subunit 6 [UDP-forming] | Arabidopsis thaliana (Mouse-ear cress) | PR |
| O49323 | CSLD1 | Cellulose synthase-like protein D1 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q8LPK5 | CESA8 | Cellulose synthase A catalytic subunit 8 [UDP-forming] | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q9SWW6 | CESA7 | Cellulose synthase A catalytic subunit 7 [UDP-forming] | Arabidopsis thaliana (Mouse-ear cress) | PR |
| 10 | 20 | 30 | 40 | 50 | 60 |
| MNTGGRLIAG | SHNRNEFVLI | NADDTARIRS | AEELSGQTCK | ICRDEIELTD | NGEPFIACNE |
| 70 | 80 | 90 | 100 | 110 | 120 |
| CAFPTCRPCY | EYERREGNQA | CPQCGTRYKR | IKGSPRVEGD | EEDDDIDDLE | HEFYGMDPEH |
| 130 | 140 | 150 | 160 | 170 | 180 |
| VTEAALYYMR | LNTGRGTDEV | SHLYSASPGS | EVPLLTYCDE | DSDMYSDRHA | LIVPPSTGLG |
| 190 | 200 | 210 | 220 | 230 | 240 |
| NRVHHVPFTD | SFASIHTRPM | VPQKDLTVYG | YGSVAWKDRM | EVWKKQQIEK | LQVVKNERVN |
| 250 | 260 | 270 | 280 | 290 | 300 |
| DGDGDGFIVD | ELDDPGLPMM | DEGRQPLSRK | LPIRSSRINP | YRMLIFCRLA | ILGLFFHYRI |
| 310 | 320 | 330 | 340 | 350 | 360 |
| LHPVNDAFGL | WLTSVICEIW | FAVSWILDQF | PKWYPIERET | YLDRLSLRYE | KEGKPSELAP |
| 370 | 380 | 390 | 400 | 410 | 420 |
| VDVFVSTVDP | LKEPPLITAN | TVLSILAVDY | PVEKVACYVS | DDGAAMLTFE | ALSYTAEFAR |
| 430 | 440 | 450 | 460 | 470 | 480 |
| KWVPFCKKFS | IEPRAPEWYF | SQKMDYLKHK | VDPAFVMERR | AMKRDYEEFK | VKINALVSVS |
| 490 | 500 | 510 | 520 | 530 | 540 |
| QKVPEDGWTM | QDGTPWPGNN | VRDHPGMIQV | FLGHSGVCDM | DGNELPRLVY | VSREKRPGFD |
| 550 | 560 | 570 | 580 | 590 | 600 |
| HHKKAGAMNS | LIRVSAVLSN | APYLLNVDCD | HYINNSKAIR | EAMCFMMDPQ | SGKKICYVQF |
| 610 | 620 | 630 | 640 | 650 | 660 |
| PQRFDGIDRH | DRYSNRNVVF | FDINMKGLDG | IQGPIYVGTG | CVFRRQALYG | FDAPKKKQPP |
| 670 | 680 | 690 | 700 | 710 | 720 |
| GRTCNCWPKW | CCLCCGMRKK | KTGKVKDNQR | KKPKETSKQI | HALEHIEEGL | QVTNAENNSE |
| 730 | 740 | 750 | 760 | 770 | 780 |
| TAQLKLEKKF | GQSPVLVAST | LLLNGGVPSN | VNPASLLRES | IQVISCGYEE | KTEWGKEIGW |
| 790 | 800 | 810 | 820 | 830 | 840 |
| IYGSVTEDIL | TGFKMHCHGW | RSVYCMPKRA | AFKGSAPINL | SDRLHQVLRW | ALGSVEIFLS |
| 850 | 860 | 870 | 880 | 890 | 900 |
| RHCPIWYGYG | GGLKWLERFS | YINSVVYPWT | SLPLLVYCSL | PAICLLTGKF | IVPEISNYAG |
| 910 | 920 | 930 | 940 | 950 | 960 |
| ILFLLMFMSI | AVTGILEMQW | GKIGIDDWWR | NEQFWVIGGV | SSHLFALFQG | LLKVLAGVST |
| 970 | 980 | 990 | 1000 | 1010 | 1020 |
| NFTVTSKAAD | DGEFSELYIF | KWTSLLIPPT | TLLIINIVGV | IVGVSDAINN | GYDSWGPLFG |
| 1030 | 1040 | 1050 | 1060 | 1070 | 1080 |
| RLFFALWVIV | HLYPFLKGLL | GKQDRVPTII | LVWSILLASI | LTLLWVRVNP | FVSKDGPVLE |
| ICGLDCLK |