O49323
PR
Gene name |
CSLD1 (At2g33100, F25I18.16) |
Protein name |
Cellulose synthase-like protein D1 |
Names |
AtCslD1 |
Species |
Arabidopsis thaliana (Mouse-ear cress) |
KEGG Pathway |
ath:AT2G33100 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for O49323
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-O49323-F1 | Predicted | AlphaFoldDB |
43 variants for O49323
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| tmp_2_14039939_C_A | 36 | V>F | No | 1000Genomes | |
| tmp_2_14039926_C_A | 40 | R>L | No | 1000Genomes | |
| ENSVATH05648048 | 43 | D>E | No | 1000Genomes | |
| ENSVATH05648047 | 47 | S>P | No | 1000Genomes | |
| tmp_2_14039766_G_C | 93 | D>E | No | 1000Genomes | |
| tmp_2_14039726_C_T | 107 | V>I | No | 1000Genomes | |
| ENSVATH13513685 | 120 | Q>K | No | 1000Genomes | |
| tmp_2_14039500_T_A | 182 | Y>F | No | 1000Genomes | |
| tmp_2_14039369_C_T | 191 | V>M | No | 1000Genomes | |
| ENSVATH05648041 | 194 | F>L | No | 1000Genomes | |
| ENSVATH00258067 | 205 | N>I | No | 1000Genomes | |
| tmp_2_14039270_A_G | 224 | F>L | No | 1000Genomes | |
| tmp_2_14039230_A_G | 237 | I>T | No | 1000Genomes | |
| ENSVATH00258066 | 244 | A>V | No | 1000Genomes | |
| tmp_2_14039129_C_T | 271 | V>I | No | 1000Genomes | |
| tmp_2_14038806_T_C | 349 | K>R | No | 1000Genomes | |
| tmp_2_14038699_G_T | 385 | Q>K | No | 1000Genomes | |
| tmp_2_14038647_T_A | 402 | K>M | No | 1000Genomes | |
| tmp_2_14038376_G_A | 468 | P>L | No | 1000Genomes | |
| tmp_2_14038365_C_T | 472 | A>T | No | 1000Genomes | |
| ENSVATH05648036 | 482 | V>I | No | 1000Genomes | |
| ENSVATH05648034 | 508 | M>L | No | 1000Genomes | |
| ENSVATH01942827 | 547 | G>S | No | 1000Genomes | |
| ENSVATH13513654 | 583 | A>V | No | 1000Genomes | |
| ENSVATH13513652 | 616 | S>T | No | 1000Genomes | |
| ENSVATH05648031 | 627 | M>L | No | 1000Genomes | |
| tmp_2_14037805_G_T | 628 | H>N | No | 1000Genomes | |
| ENSVATH05648030 | 677 | E>K | No | 1000Genomes | |
| ENSVATH01942824 | 697 | A>S | No | 1000Genomes | |
| ENSVATH05648029 | 703 | P>L | No | 1000Genomes | |
| tmp_2_14037580_G_A | 703 | P>S | No | 1000Genomes | |
| tmp_2_14037329_A_T | 759 | I>N | No | 1000Genomes | |
| ENSVATH13513651 | 791 | F>V | No | 1000Genomes | |
| tmp_2_14037211_C_T | 798 | M>I | No | 1000Genomes | |
| ENSVATH05648025 | 873 | G>R | No | 1000Genomes | |
| tmp_2_14036981_C_T | 875 | G>E | No | 1000Genomes | |
| tmp_2_14036918_G_C | 896 | A>G | No | 1000Genomes | |
| tmp_2_14036832_C_G | 925 | D>H | No | 1000Genomes | |
| ENSVATH13513650 | 929 | A>E | No | 1000Genomes | |
| tmp_2_14036706_G_T | 967 | P>T | No | 1000Genomes | |
| tmp_2_14036655_T_C | 984 | T>A | No | 1000Genomes | |
| tmp_2_14036636_G_A | 990 | A>V | No | 1000Genomes | |
| ENSVATH01942818 | 1034 | I>V | No | 1000Genomes |
No associated diseases with O49323
No regional properties for O49323
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| No domain, repeats, and functional sites for O49323 | |||
3 GO annotations of cellular component
| Name | Definition |
|---|---|
| Golgi membrane | The lipid bilayer surrounding any of the compartments of the Golgi apparatus. |
| integral component of membrane | The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane. |
| plasma membrane | The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins. |
2 GO annotations of molecular function
| Name | Definition |
|---|---|
| cellulose synthase (UDP-forming) activity | Catalysis of the reaction: UDP-glucose + ((1,4)-beta-D-glucosyl)(n) = UDP + ((1,4)-beta-D-glucosyl)(n+1). |
| mannan synthase activity | Catalysis of the reaction: mannan(n) + GDP-mannose = mannan(n+1) + GDP. This reaction is the formation of the beta-(1->4)-linked mannan backbone in substrates such as galactomannan. |
4 GO annotations of biological process
| Name | Definition |
|---|---|
| cell wall organization | A process that results in the assembly, arrangement of constituent parts, or disassembly of the cell wall, the rigid or semi-rigid envelope lying outside the cell membrane of plant, fungal and most prokaryotic cells, maintaining their shape and protecting them from osmotic lysis. |
| cellulose biosynthetic process | The chemical reactions and pathways resulting in the formation of cellulose, a linear beta1-4 glucan of molecular mass 50-400 kDa with the pyranose units in the -4C1 conformation. |
| plant-type primary cell wall biogenesis | A cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of cellulose and pectin-containing cell walls that form adjacent to the middle lamella following cell division and during cell expansion. An example of this is found in Arabidopsis thaliana. |
| pollen germination | The physiological and developmental changes that occur in a heterosporous plant pollen grain, beginning with hydration and terminating with the emergence of the pollen tube through the aperture. |
5 homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| Q9SJ22 | CESA9 | Probable cellulose synthase A catalytic subunit 9 [UDP-forming] | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q8LPK5 | CESA8 | Cellulose synthase A catalytic subunit 8 [UDP-forming] | Arabidopsis thaliana (Mouse-ear cress) | PR |
| O48947 | CESA2 | Cellulose synthase A catalytic subunit 2 [UDP-forming] | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q9SWW6 | CESA7 | Cellulose synthase A catalytic subunit 7 [UDP-forming] | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q94JQ6 | CESA6 | Cellulose synthase A catalytic subunit 6 [UDP-forming] | Arabidopsis thaliana (Mouse-ear cress) | PR |
| 10 | 20 | 30 | 40 | 50 | 60 |
| MASSPPKKTL | NSQSSSLSRP | PQAVKFGRRT | SSGRIVSLSR | DDDMDVSGDY | SGQNDYINYT |
| 70 | 80 | 90 | 100 | 110 | 120 |
| VLMPPTPDNQ | PAGSSGSTSE | SKGDANRGGG | GGDGPKMGNK | LERRLSVMKS | NNKSMLLRSQ |
| 130 | 140 | 150 | 160 | 170 | 180 |
| TGDFDHNRWL | FESKGKYGIG | NAFWSEEDDT | YDGGVSKSDF | LDKPWKPLTR | KVQIPAKILS |
| 190 | 200 | 210 | 220 | 230 | 240 |
| PYRLLIVIRL | VIVFFFLWWR | ITNPNEDAMW | LWGLSIVCEI | WFAFSWILDI | LPKLNPINRA |
| 250 | 260 | 270 | 280 | 290 | 300 |
| TDLAALHDKF | EQPSPSNPTG | RSDLPGVDVF | VSTADPEKEP | PLVTANTLLS | ILAVDYPIEK |
| 310 | 320 | 330 | 340 | 350 | 360 |
| LSAYISDDGG | AILTFEAMAE | AVRFAEYWVP | FCRKHDIEPR | NPDSYFSIKK | DPTKNKKRQD |
| 370 | 380 | 390 | 400 | 410 | 420 |
| FVKDRRWIKR | EYDEFKVRIN | GLPEQIKKRA | EQFNMREELK | EKRIAREKNG | GVLPPDGVEV |
| 430 | 440 | 450 | 460 | 470 | 480 |
| VKATWMADGT | HWPGTWFEPK | PDHSKGDHAG | ILQIMSKVPD | LEPVMGGPNE | GALDFTGIDI |
| 490 | 500 | 510 | 520 | 530 | 540 |
| RVPMFAYVSR | EKRPGFDHNK | KAGAMNGMVR | ASAILSNGAF | ILNLDCDHYI | YNSKAIKEGM |
| 550 | 560 | 570 | 580 | 590 | 600 |
| CFMMDRGGDR | ICYIQFPQRF | EGIDPSDRYA | NHNTVFFDGN | MRALDGLQGP | VYVGTGCMFR |
| 610 | 620 | 630 | 640 | 650 | 660 |
| RYALYGFNPP | RANEYSGVFG | QEKAPAMHVR | TQSQASQTSQ | ASDLESDTQP | LNDDPDLGLP |
| 670 | 680 | 690 | 700 | 710 | 720 |
| KKFGNSTMFT | DTIPVAEYQG | RPLADHMSVK | NGRPPGALLL | PRPPLDAPTV | AEAIAVISCW |
| 730 | 740 | 750 | 760 | 770 | 780 |
| YEDNTEWGDR | IGWIYGSVTE | DVVTGYRMHN | RGWRSVYCIT | KRDAFRGTAP | INLTDRLHQV |
| 790 | 800 | 810 | 820 | 830 | 840 |
| LRWATGSVEI | FFSKNNAMFA | TRRLKFLQRV | AYLNVGIYPF | TSIFLVVYCF | LPALCLFSGK |
| 850 | 860 | 870 | 880 | 890 | 900 |
| FIVQSLDIHF | LSYLLCITVT | LTLISLLEVK | WSGIGLEEWW | RNEQFWLIGG | TSAHLAAVVQ |
| 910 | 920 | 930 | 940 | 950 | 960 |
| GLLKVIAGIE | ISFTLTSKAS | GEDEDDIFAD | LYIVKWTGLF | IMPLTIIIVN | LVAIVIGASR |
| 970 | 980 | 990 | 1000 | 1010 | 1020 |
| TIYSVIPQWG | KLMGGIFFSL | WVLTHMYPFA | KGLMGRRGKV | PTIVYVWSGL | VSITVSLLWI |
| 1030 | |||||
| TISPPDDVSG | SGGISV |