Q9M2Q4
PR
Gene name |
At3g57940 (T10K17.150) |
Protein name |
RNA cytidine acetyltransferase 2 |
Names |
18S rRNA cytosine acetyltransferase 2 |
Species |
Arabidopsis thaliana (Mouse-ear cress) |
KEGG Pathway |
ath:AT3G57940 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q9M2Q4
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q9M2Q4-F1 | Predicted | AlphaFoldDB |
67 variants for Q9M2Q4
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| tmp_3_21449579_A_G | 7 | E>G | No | 1000Genomes | |
| ENSVATH06335485 | 15 | N>K | No | 1000Genomes | |
| tmp_3_21449612_A_T | 18 | K>I | No | 1000Genomes | |
| ENSVATH02519589 | 42 | M>L | No | 1000Genomes | |
| ENSVATH06335489 | 67 | H>N | No | 1000Genomes | |
| tmp_3_21450097_C_T | 86 | P>S | No | 1000Genomes | |
| tmp_3_21450170_A_G | 110 | E>G | No | 1000Genomes | |
| tmp_3_21450518_G_A | 165 | D>N | No | 1000Genomes | |
| ENSVATH02519609 | 173 | E>D | No | 1000Genomes | |
| ENSVATH06335496 | 173 | E>K | No | 1000Genomes | |
| tmp_3_21450611_T_A | 196 | C>S | No | 1000Genomes | |
| ENSVATH06335498 | 197 | V>I | No | 1000Genomes | |
| tmp_3_21450668_A_C | 215 | I>L | No | 1000Genomes | |
| ENSVATH14449067 | 215 | I>T | No | 1000Genomes | |
| ENSVATH12813262 | 220 | T>A | No | 1000Genomes | |
| tmp_3_21450776_A_G | 223 | D>G | No | 1000Genomes | |
| tmp_3_21450803_G_A | 232 | R>Q | No | 1000Genomes | |
| ENSVATH14449068 | 267 | F>L | No | 1000Genomes | |
| ENSVATH06335505 | 277 | S>N | No | 1000Genomes | |
| ENSVATH12813310 | 293 | L>F | No | 1000Genomes | |
| ENSVATH14449069 | 298 | A>T | No | 1000Genomes | |
| tmp_3_21451106_C_T | 302 | A>V | No | 1000Genomes | |
| tmp_3_21451247_C_T | 315 | P>S | No | 1000Genomes | |
| ENSVATH02519618 | 375 | H>Y | No | 1000Genomes | |
| ENSVATH12813335 | 433 | Q>R | No | 1000Genomes | |
| ENSVATH06335510 | 439 | T>S | No | 1000Genomes | |
| ENSVATH06335511 | 444 | S>C | No | 1000Genomes | |
| tmp_3_21452404_A_T | 451 | I>L | No | 1000Genomes | |
| ENSVATH12813338 | 484 | P>R | No | 1000Genomes | |
| ENSVATH06335516 | 484 | P>S | No | 1000Genomes | |
| tmp_3_21452785_C_T | 519 | A>V | No | 1000Genomes | |
| tmp_3_21452803_A_G | 525 | H>R | No | 1000Genomes | |
| ENSVATH12813340 | 529 | S>C | No | 1000Genomes | |
| tmp_3_21452860_T_C | 544 | L>S | No | 1000Genomes | |
| tmp_3_21452958_G_T | 553 | E>D | No | 1000Genomes | |
| tmp_3_21452960_C_T | 554 | S>F | No | 1000Genomes | |
| tmp_3_21453207_G_A | 568 | C>Y | No | 1000Genomes | |
| tmp_3_21453272_G_A | 590 | G>R | No | 1000Genomes | |
| ENSVATH14449071 | 602 | R>Q | No | 1000Genomes | |
| tmp_3_21453486_G_C | 633 | V>L | No | 1000Genomes | |
| ENSVATH12813344 | 637 | T>A | No | 1000Genomes | |
| tmp_3_21453677_A_T | 647 | I>F | No | 1000Genomes | |
| tmp_3_21453680_T_G | 648 | S>A | No | 1000Genomes | |
| ENSVATH12813377 | 652 | D>E | No | 1000Genomes | |
| tmp_3_21453710_C_T | 658 | H>Y | No | 1000Genomes | |
| ENSVATH06335533 | 699 | H>Q | No | 1000Genomes | |
| ENSVATH06335534 | 710 | D>G | No | 1000Genomes | |
| ENSVATH14449073 | 719 | N>K | No | 1000Genomes | |
| ENSVATH06335536 | 728 | I>L | No | 1000Genomes | |
| ENSVATH06335539 | 745 | K>R | No | 1000Genomes | |
| tmp_3_21454488_A_T | 794 | K>M | No | 1000Genomes | |
| ENSVATH02519648 | 810 | F>L | No | 1000Genomes | |
| tmp_3_21454553_G_A | 816 | G>S | No | 1000Genomes | |
| tmp_3_21454556_A_T | 817 | I>L | No | 1000Genomes | |
| ENSVATH14449105 | 839 | V>F | No | 1000Genomes | |
| ENSVATH06335545 | 877 | F>V | No | 1000Genomes | |
| ENSVATH00425356 | 899 | A>V | No | 1000Genomes | |
| ENSVATH06335548 | 916 | S>L | No | 1000Genomes | |
| tmp_3_21455156_G_C | 917 | A>P | No | 1000Genomes | |
| ENSVATH00425360 | 935 | D>N | No | 1000Genomes | |
| ENSVATH06335555 | 971 | A>S | No | 1000Genomes | |
| ENSVATH06335556 | 973 | A>P | No | 1000Genomes | |
| tmp_3_21455706_G_C | 987 | V>L | No | 1000Genomes | |
| tmp_3_21455730_G_A | 995 | E>K | No | 1000Genomes | |
| ENSVATH06335557 | 1008 | D>Y | No | 1000Genomes | |
| ENSVATH02519662 | 1009 | K>R | No | 1000Genomes | |
| ENSVATH14449107 | 1017 | S>P | No | 1000Genomes |
No associated diseases with Q9M2Q4
No regional properties for Q9M2Q4
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| No domain, repeats, and functional sites for Q9M2Q4 | |||
1 GO annotations of cellular component
| Name | Definition |
|---|---|
| nucleolus | A small, dense body one or more of which are present in the nucleus of eukaryotic cells. It is rich in RNA and protein, is not bounded by a limiting membrane, and is not seen during mitosis. Its prime function is the transcription of the nucleolar DNA into 45S ribosomal-precursor RNA, the processing of this RNA into 5.8S, 18S, and 28S components of ribosomal RNA, and the association of these components with 5S RNA and proteins synthesized outside the nucleolus. This association results in the formation of ribonucleoprotein precursors; these pass into the cytoplasm and mature into the 40S and 60S subunits of the ribosome. |
3 GO annotations of molecular function
| Name | Definition |
|---|---|
| ATP binding | Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator. |
| rRNA cytidine N-acetyltransferase activity | Catalysis of the reaction: acetyl-CoA + cytidine = CoA + N4-acetylcytidine. The cytidine is within the polynucleotide chain of an rRNA. |
| tRNA binding | Binding to a transfer RNA. |
2 GO annotations of biological process
| Name | Definition |
|---|---|
| rRNA acetylation involved in maturation of SSU-rRNA | Any rRNA acetylation that is involved in maturation of SSU-rRNA. |
| tRNA acetylation | The modification of tRNA structure by addition of an acetyl group to tRNA. An acetyl group is CH3CO-, derived from acetic |
5 homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| P53914 | KRE33 | RNA cytidine acetyltransferase | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) | PR |
| Q9H0A0 | NAT10 | RNA cytidine acetyltransferase | Homo sapiens (Human) | PR |
| Q8K224 | Nat10 | RNA cytidine acetyltransferase | Mus musculus (Mouse) | PR |
| O01757 | nath-10 | RNA cytidine acetyltransferase | Caenorhabditis elegans | PR |
| Q9XIK4 | At1g10490 | RNA cytidine acetyltransferase 1 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| 10 | 20 | 30 | 40 | 50 | 60 |
| MRKKVDERIR | TLIENGVKLR | HRSMFVIIGD | KSRDQIVNLH | HMLSKAVIKC | NPSVLWCYKD |
| 70 | 80 | 90 | 100 | 110 | 120 |
| KLDISSHKQK | RSKQLKRLRE | RGQLDPEKLD | AFSRLLDVGR | VTHCLYKDSE | RILGNTFGMC |
| 130 | 140 | 150 | 160 | 170 | 180 |
| ILQDFEALTP | NLLARTIETV | EGGGLVVLIL | RSLTSLTSLC | TMVMDVHDRF | RTESHSEAAG |
| 190 | 200 | 210 | 220 | 230 | 240 |
| RFNERFLLSL | ASCKACVVMD | DELNILPLSS | HIRSITQVPT | EKDSEGLSEA | ERDLKSLKED |
| 250 | 260 | 270 | 280 | 290 | 300 |
| LSDDFPVGPL | IKKCCTLDQG | KAVVTFFDAI | LDKALRSIVA | LIASRGRGKS | AALGLAVAGA |
| 310 | 320 | 330 | 340 | 350 | 360 |
| VAAGYSNIYI | TAPSPDNLKT | FFEFVCKGFD | ALEYKEHLDY | DVVKSANPDF | KKAVVRINIF |
| 370 | 380 | 390 | 400 | 410 | 420 |
| KQHRQTIQYI | QPHEHEKLSQ | VELLVIDEAA | AIPLPVVKSL | LGPYLVFLSS | TVSGYEGTGR |
| 430 | 440 | 450 | 460 | 470 | 480 |
| SLSLKLLQQL | DEQSRAPATG | LEGSGCLFKK | IELTESIRYG | SGDPIESWLN | GLLCLDVATC |
| 490 | 500 | 510 | 520 | 530 | 540 |
| LPNPACHPSP | SQCDLYYVNR | DTLFSYHKDS | ELFLQRMMAL | CVSSHYKNSP | NDLQLLADAP |
| 550 | 560 | 570 | 580 | 590 | 600 |
| AHHLFVLLGP | VDESQNKIPD | ILCVIQVCLE | GKISENSALQ | SLRDGHSPYG | DQIPWKFCEQ |
| 610 | 620 | 630 | 640 | 650 | 660 |
| FRDTEFPGFS | GARIVRIAVH | PNAMKMGYGS | AAVELLTRYF | EGQIAPISEA | EDKVDVEHAP |
| 670 | 680 | 690 | 700 | 710 | 720 |
| IKVTEAAEKV | SMLEEQVKPR | TNLPPLLVPL | HDRRPEKLHY | IGVSFGLTLD | LFRFWRKHNF |
| 730 | 740 | 750 | 760 | 770 | 780 |
| APFYVSQIPS | AVTGEHTCML | LKPLKNDELE | VNESDELGFF | TPFYKDFKIR | FSKLLSDKFK |
| 790 | 800 | 810 | 820 | 830 | 840 |
| KMDYKLAMSV | LNPKINFAEV | DSSGSSSGGF | LKTLNGILSP | YDMERLRAYT | ENLTDFNLVY |
| 850 | 860 | 870 | 880 | 890 | 900 |
| DICKTLAHQY | FEEKLPVSLS | YVQASILLCL | GLQETDFSSI | ERQMQLERGQ | IHSLLLKVAR |
| 910 | 920 | 930 | 940 | 950 | 960 |
| ELYKYLNGVA | GKEIKSALPR | LKERELTAHN | VSVDDDIREG | AKQVEEQMKK | EKIEGLMDSE |
| 970 | 980 | 990 | 1000 | 1010 | 1020 |
| LQQYVIGDKE | AEALQHSKIS | SSGIISVKST | KSENENGFDK | STKKRSSDKR | SSSSSKSKSS |
| KKRKSLKE |