Q9LZ20
Gene name |
CAT6 (At5g04770, T1E3.130) |
Protein name |
Cationic amino acid transporter 6, chloroplastic |
Names |
|
Species |
Arabidopsis thaliana (Mouse-ear cress) |
KEGG Pathway |
ath:AT5G04770 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q9LZ20
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q9LZ20-F1 | Predicted | AlphaFoldDB |
38 variants for Q9LZ20
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| tmp_5_1379188_C_T | 24 | S>F | No | 1000Genomes | |
| tmp_5_1379212_T_C | 32 | L>S | No | 1000Genomes | |
| ENSVATH06922915 | 32 | L>V | No | 1000Genomes | |
| tmp_5_1379233_T_C | 39 | V>A | No | 1000Genomes | |
| ENSVATH06922916 | 43 | S>T | No | 1000Genomes | |
| ENSVATH13924412 | 48 | R>C | No | 1000Genomes | |
| tmp_5_1379262_G_A | 49 | V>I | No | 1000Genomes | |
| tmp_5_1379269_C_A | 51 | A>D | No | 1000Genomes | |
| tmp_5_1379277_G_A | 54 | G>S | No | 1000Genomes | |
| tmp_5_1379296_C_T | 60 | T>I | No | 1000Genomes | |
| ENSVATH06922917 | 67 | I>T | No | 1000Genomes | |
| tmp_5_1379352_G_A | 79 | V>I | No | 1000Genomes | |
| tmp_5_1379358_G_T | 81 | V>F | No | 1000Genomes | |
| ENSVATH06922918 | 97 | V>L | No | 1000Genomes | |
| ENSVATH00606845 | 122 | V>I | No | 1000Genomes | |
| tmp_5_1379742_G_A | 170 | G>E | No | 1000Genomes | |
| tmp_5_1379786_A_C | 185 | K>Q | No | 1000Genomes | |
| ENSVATH06922922 | 196 | L>F | No | 1000Genomes | |
| tmp_5_1379884_G_A | 217 | M>I | No | 1000Genomes | |
| tmp_5_1379927_G_C | 232 | V>L | No | 1000Genomes | |
| tmp_5_1379948_G_C | 239 | D>H | No | 1000Genomes | |
| ENSVATH10573784 | 250 | E>G | No | 1000Genomes | |
| tmp_5_1380071_G_A | 280 | V>I | No | 1000Genomes | |
| ENSVATH06922930 | 327 | P>A | No | 1000Genomes | |
| tmp_5_1380340_C_T | 332 | S>F | No | 1000Genomes | |
| ENSVATH00606848 | 333 | A>E | No | 1000Genomes | |
| tmp_5_1380350_C_A | 335 | F>L | No | 1000Genomes | |
| ENSVATH06922932 | 339 | N>D | No | 1000Genomes | |
| tmp_5_1380447_G_A | 368 | A>T | No | 1000Genomes | |
| tmp_5_1381853_A_C | 434 | N>T | No | 1000Genomes | |
| tmp_5_1381880_C_A | 443 | P>Q | No | 1000Genomes | |
| tmp_5_1381907_C_T | 452 | T>I | No | 1000Genomes | |
| ENSVATH06922954 | 520 | C>S | No | 1000Genomes | |
| ENSVATH06922955 | 521 | V>L | No | 1000Genomes | |
| ENSVATH06922956 | 545 | S>F | No | 1000Genomes | |
| ENSVATH06922958 | 568 | S>Y | No | 1000Genomes | |
| ENSVATH10573901 | 579 | E>Q | No | 1000Genomes | |
| ENSVATH03023638 | 581 | I>M | No | 1000Genomes |
No associated diseases with Q9LZ20
5 regional properties for Q9LZ20
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| domain | TolB, N-terminal | 22 - 128 | IPR007195 |
| repeat | WD40-like beta propeller | 242 - 271 | IPR011659-1 |
| repeat | WD40-like beta propeller | 282 - 316 | IPR011659-2 |
| repeat | WD40-like beta propeller | 325 - 349 | IPR011659-3 |
| repeat | WD40-like beta propeller | 377 - 400 | IPR011659-4 |
3 GO annotations of cellular component
| Name | Definition |
|---|---|
| chloroplast membrane | Either of the lipid bilayers that surround a chloroplast and form the chloroplast envelope. |
| integral component of membrane | The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane. |
| plasma membrane | The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins. |
1 GO annotations of molecular function
| Name | Definition |
|---|---|
| amino acid transmembrane transporter activity | Enables the transfer of amino acids from one side of a membrane to the other. Amino acids are organic molecules that contain an amino group and a carboxyl group. |
2 GO annotations of biological process
| Name | Definition |
|---|---|
| amino acid transport | The directed movement of amino acids, organic acids containing one or more amino substituents, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. |
| response to nematode | Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from a nematode. |
8 homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| P30825 | SLC7A1 | High affinity cationic amino acid transporter 1 | Homo sapiens (Human) | PR |
| Q8WY07 | SLC7A3 | Cationic amino acid transporter 3 | Homo sapiens (Human) | PR |
| P70423 | Slc7a3 | Cationic amino acid transporter 3 | Mus musculus (Mouse) | PR |
| Q09143 | Slc7a1 | High affinity cationic amino acid transporter 1 | Mus musculus (Mouse) | PR |
| O08812 | Slc7a3 | Cationic amino acid transporter 3 | Rattus norvegicus (Rat) | PR |
| P30823 | Slc7a1 | High affinity cationic amino acid transporter 1 | Rattus norvegicus (Rat) | PR |
| Q84MA5 | CAT1 | Cationic amino acid transporter 1 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q5PR34 | slc7a2 | Cationic amino acid transporter 2 | Danio rerio (Zebrafish) (Brachydanio rerio) | PR |
| 10 | 20 | 30 | 40 | 50 | 60 |
| MEVQSSSNNG | GHSSFSSLRV | YLNSLSATPS | RLSRRAISVS | TSSDEMSRVR | AVSGEQMRRT |
| 70 | 80 | 90 | 100 | 110 | 120 |
| LRWYDLIGLG | IGGMVGAGVF | VTTGRASRLD | AGPSIVVSYA | IAGLCALLSA | FCYTEFAVHL |
| 130 | 140 | 150 | 160 | 170 | 180 |
| PVAGGAFSYI | RITFGEFPAF | FTGANLVMDY | VMSNAAVSRS | FTAYLGTAFG | ISTSKWRFVV |
| 190 | 200 | 210 | 220 | 230 | 240 |
| SGLPKGFNEI | DPVAVLVVLV | ITVIICCSTR | ESSKVNMIMT | AFHIAFIFFV | IVMGFIKGDS |
| 250 | 260 | 270 | 280 | 290 | 300 |
| KNLSSPANPE | HPSGFFPFGA | AGVFNGAAMV | YLSYIGYDAV | STMAEEVENP | VKDIPVGVSG |
| 310 | 320 | 330 | 340 | 350 | 360 |
| SVAIVTVLYC | LMAVSMSMLL | PYDLIDPEAP | FSAAFRGSNG | WEWVTKVVGI | GASFGILTSL |
| 370 | 380 | 390 | 400 | 410 | 420 |
| LVAMLGQARY | MCVIGRSRVV | PFWFAKIHPK | TSTPVNASTF | LGIFTAALAL | FTDLNVLLNL |
| 430 | 440 | 450 | 460 | 470 | 480 |
| VSIGTLFVFY | MVANALIFRR | YVPVGPTKPW | PTLCFLTLFS | ITSLVFTLIW | KLVPEGKPKA |
| 490 | 500 | 510 | 520 | 530 | 540 |
| FMLGASAVVA | IAIVLSFQCV | VPQARKPELW | GVPFMPWTPC | VSIFLNIFLL | GSLDAPSYVR |
| 550 | 560 | 570 | 580 | ||
| FGFFSGLIVL | VYLFYGVHAS | SDAEANGSFG | VKDGQVMKEL | IEV |