Q5PR34
Gene name |
slc7a2 (zgc:103686) |
Protein name |
Cationic amino acid transporter 2 |
Names |
CAT-2, CAT2, Low affinity cationic amino acid transporter 2, Solute carrier family 7 member 2 |
Species |
Danio rerio (Zebrafish) (Brachydanio rerio) |
KEGG Pathway |
dre:494041 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q5PR34
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q5PR34-F1 | Predicted | AlphaFoldDB |
No variants for Q5PR34
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for Q5PR34 | |||||
No associated diseases with Q5PR34
1 regional properties for Q5PR34
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| domain | Cationic amino acid transporter, C-terminal | 552 - 602 | IPR029485 |
2 GO annotations of cellular component
| Name | Definition |
|---|---|
| integral component of membrane | The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane. |
| plasma membrane | The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins. |
3 GO annotations of molecular function
| Name | Definition |
|---|---|
| amino acid transmembrane transporter activity | Enables the transfer of amino acids from one side of a membrane to the other. Amino acids are organic molecules that contain an amino group and a carboxyl group. |
| L-lysine transmembrane transporter activity | Enables the transfer of L-lysine from one side of a membrane to the other. L-lysine is 2,6-diaminohexanoic acid. |
| L-ornithine transmembrane transporter activity | Enables the transfer of L-ornithine from one side of a membrane to the other. L-ornithine is 2,5-diaminopentanoic acid. |
4 GO annotations of biological process
| Name | Definition |
|---|---|
| amino acid transport | The directed movement of amino acids, organic acids containing one or more amino substituents, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. |
| L-arginine import across plasma membrane | The directed movement of L-arginine from outside of a cell, across the plasma membrane and into the cytosol. |
| L-arginine transmembrane transport | The directed movement of L-arginine across a membrane. |
| L-ornithine transmembrane transport | The directed movement of L-ornithine across a membrane. |
8 homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| Q8WY07 | SLC7A3 | Cationic amino acid transporter 3 | Homo sapiens (Human) | PR |
| P30825 | SLC7A1 | High affinity cationic amino acid transporter 1 | Homo sapiens (Human) | PR |
| Q09143 | Slc7a1 | High affinity cationic amino acid transporter 1 | Mus musculus (Mouse) | PR |
| P70423 | Slc7a3 | Cationic amino acid transporter 3 | Mus musculus (Mouse) | PR |
| P30823 | Slc7a1 | High affinity cationic amino acid transporter 1 | Rattus norvegicus (Rat) | PR |
| O08812 | Slc7a3 | Cationic amino acid transporter 3 | Rattus norvegicus (Rat) | PR |
| Q84MA5 | CAT1 | Cationic amino acid transporter 1 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q9LZ20 | CAT6 | Cationic amino acid transporter 6, chloroplastic | Arabidopsis thaliana (Mouse-ear cress) | PR |
| 10 | 20 | 30 | 40 | 50 | 60 |
| MLEHCLTFGR | SLVRRKNVDQ | GCLEESKLCR | CLSTVDLIAL | GVGSTLGAGV | YVLAGEVAKG |
| 70 | 80 | 90 | 100 | 110 | 120 |
| SSGPSIVVSF | LIAALASVMA | GLCYAEFGAR | VPKTGSAYLY | SYVTVGELWA | FITGWNLILS |
| 130 | 140 | 150 | 160 | 170 | 180 |
| YVIGTSSVAR | AWSGTFDEII | GGHIEKFCKM | YFKMSLPGLA | EYPDFFAVCL | ILLLSGLLSF |
| 190 | 200 | 210 | 220 | 230 | 240 |
| GVKESAWVNK | IFTAVNVLVL | MFVIISGFVK | GDSLNWNISE | ESLVNITVVK | RNISSAANVT |
| 250 | 260 | 270 | 280 | 290 | 300 |
| SDYGAGGFFP | YGFGGTLAGA | ATCFYAFVGF | DCIATTGEEV | KNPQRAIPIG | IVVSLLVCFL |
| 310 | 320 | 330 | 340 | 350 | 360 |
| AYFGVSAALT | LMMPYYLLDE | KSPLPLAFEY | VGWGPAKYVV | AAGSLCALST | SLLGSMFPLP |
| 370 | 380 | 390 | 400 | 410 | 420 |
| RILFAMARDG | VLFRFLSKLS | KRQSPVAATM | AAGTTAAIMA | FLFDLKALVD | MMSIGTLLAY |
| 430 | 440 | 450 | 460 | 470 | 480 |
| SLVAACVLIL | RYQPDASFER | SRISEGKEEV | GESELTESES | HLNMLKDGGV | TLRSLLHPPL |
| 490 | 500 | 510 | 520 | 530 | 540 |
| LPTENTSSVV | NVSVIITVLV | VCVVSTLNTY | YGQAIIAMEL | WALGVLAASL | FIFIICVFLI |
| 550 | 560 | 570 | 580 | 590 | 600 |
| CRQPQTRKKV | SFMVPLLPFL | PILSIFVNVY | LMVQLSGDTW | IRFSIWMAIG | FLIYFGYGMW |
| 610 | 620 | 630 | |||
| HSDERKRHLQ | NCAVATEKKT | LTGNEGFVEN | KTHTEKTSPC |