Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

Autoinhibited structure

Activated structure

1 structures for Q9LTS3

Entry ID Method Resolution Chain Position Source
AF-Q9LTS3-F1 Predicted AlphaFoldDB

63 variants for Q9LTS3

Variant ID(s) Position Change Description Diseaes Association Provenance
tmp_5_23048236_A_T 4 Y>N No 1000Genomes
tmp_5_23048218_C_T 10 V>I No 1000Genomes
tmp_5_23048211_A_T 12 L>H No 1000Genomes
tmp_5_23048205_G_A 14 A>V No 1000Genomes
tmp_5_23048193_A_C 18 V>G No 1000Genomes
tmp_5_23048164_T_C 28 T>A No 1000Genomes
tmp_5_23048114_G_T 44 F>L No 1000Genomes
tmp_5_23048113_C_G 45 A>P No 1000Genomes
ENSVATH07436831 52 S>F No 1000Genomes
ENSVATH07436830 60 T>I No 1000Genomes
tmp_5_23048055_T_A 64 H>L No 1000Genomes
ENSVATH00738325 75 I>N No 1000Genomes
ENSVATH12816789 84 D>N No 1000Genomes
ENSVATH03441990 97 P>S No 1000Genomes
tmp_5_23047885_T_C 121 M>V No 1000Genomes
ENSVATH12816788 129 R>Q No 1000Genomes
ENSVATH00738324 135 R>G No 1000Genomes
ENSVATH00738323 137 C>G No 1000Genomes
tmp_5_23047816_C_A 144 A>S No 1000Genomes
tmp_5_23047813_C_T 145 A>T No 1000Genomes
ENSVATH07436828 155 T>S No 1000Genomes
tmp_5_23047780_A_T 156 L>M No 1000Genomes
ENSVATH12816784 163 V>A No 1000Genomes
ENSVATH12816785 163 V>I No 1000Genomes
tmp_5_23046153_T_A 215 M>L No 1000Genomes
ENSVATH03441938 234 T>I No 1000Genomes
ENSVATH07436776 241 E>K No 1000Genomes
ENSVATH07436775 245 K>T No 1000Genomes
tmp_5_23045912_C_A 267 V>L No 1000Genomes
ENSVATH00738315 281 I>V No 1000Genomes
tmp_5_23045818_G_T 298 P>Q No 1000Genomes
ENSVATH12816644 305 A>G No 1000Genomes
ENSVATH12816643 306 S>A No 1000Genomes
tmp_5_23045773_A_G 313 V>A No 1000Genomes
ENSVATH07436774 313 V>I No 1000Genomes
ENSVATH14636628 357 M>I No 1000Genomes
tmp_5_23045541_T_A 357 M>L No 1000Genomes
ENSVATH12816638 360 L>V No 1000Genomes
tmp_5_23045519_C_A 364 R>L No 1000Genomes
tmp_5_23045492_T_C 373 K>R No 1000Genomes
ENSVATH14636627 394 K>T No 1000Genomes
tmp_5_23045412_A_T 400 F>I No 1000Genomes
ENSVATH12816636 400 F>L No 1000Genomes
ENSVATH14636626 402 G>D No 1000Genomes
ENSVATH07436770 416 V>I No 1000Genomes
ENSVATH12816614 425 N>H No 1000Genomes
ENSVATH14636625 430 A>V No 1000Genomes
tmp_5_23045209_T_C 436 D>G No 1000Genomes
ENSVATH07436764 447 A>V No 1000Genomes
ENSVATH12816613 448 G>D No 1000Genomes
ENSVATH07436763 450 D>G No 1000Genomes
tmp_5_23045156_C_G 454 A>P No 1000Genomes
ENSVATH07436762 455 F>Y No 1000Genomes
tmp_5_23045129_G_T 463 L>M No 1000Genomes
tmp_5_23045125_T_C 464 K>R No 1000Genomes
ENSVATH07436761 471 M>V No 1000Genomes
ENSVATH03441934 472 G>R No 1000Genomes
tmp_5_23045062_C_T 485 G>E No 1000Genomes
ENSVATH07436760 485 G>R No 1000Genomes
ENSVATH00738307 488 R>K Plants were checked bi-weekly for presence of first buds and the average flowering time of 4 plants of the same accession were collected [16c and 16 hrs daylight] [EnsemblGenome] No 1000Genomes
tmp_5_23045008_T_A 503 K>I No 1000Genomes
tmp_5_23044991_T_A 509 I>L No 1000Genomes
ENSVATH07436759 523 S>T No 1000Genomes

1 associated diseases with Q9LTS3

Without disease ID

2 regional properties for Q9LTS3

Type Name Position InterPro Accession
domain CBS domain 601 - 657 IPR000644-1
domain CBS domain 806 - 868 IPR000644-2

Functions

Description
EC Number 1.5.99.12 With other acceptors
Subcellular Localization
  • Endoplasmic reticulum
  • Vacuole
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

2 GO annotations of cellular component

Name Definition
endoplasmic reticulum The irregular network of unit membranes, visible only by electron microscopy, that occurs in the cytoplasm of many eukaryotic cells. The membranes form a complex meshwork of tubular channels, which are often expanded into slitlike cavities called cisternae. The ER takes two forms, rough (or granular), with ribosomes adhering to the outer surface, and smooth (with no ribosomes attached).
vacuole A closed structure, found only in eukaryotic cells, that is completely surrounded by unit membrane and contains liquid material. Cells contain one or several vacuoles, that may have different functions from each other. Vacuoles have a diverse array of functions. They can act as a storage organelle for nutrients or waste products, as a degradative compartment, as a cost-effective way of increasing cell size, and as a homeostatic regulator controlling both turgor pressure and pH of the cytosol.

4 GO annotations of molecular function

Name Definition
cytokinin dehydrogenase activity Catalysis of the reaction: N6-dimethylallyladenine + acceptor + H2O = adenine + 3-methylbut-2-enal + reduced electron acceptor.
FAD binding Binding to the oxidized form, FAD, of flavin-adenine dinucleotide, the coenzyme or the prosthetic group of various flavoprotein oxidoreductase enzymes.
oxidoreductase activity Catalysis of an oxidation-reduction (redox) reaction, a reversible chemical reaction in which the oxidation state of an atom or atoms within a molecule is altered. One substrate acts as a hydrogen or electron donor and becomes oxidized, while the other acts as hydrogen or electron acceptor and becomes reduced.
primary amine oxidase activity Catalysis of the reaction: a primary amine + H2O + O2 = an aldehyde + NH3 + hydrogen peroxide.

1 GO annotations of biological process

Name Definition
cytokinin catabolic process The chemical reactions and pathways resulting in the breakdown of cytokinins, a class of adenine-derived compounds that can function in plants as plant growth regulators.

8 homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
Q5JLP4 CKX4 Cytokinin dehydrogenase 4 Oryza sativa subsp japonica (Rice) PR
A3AVP1 CKX8 Cytokinin dehydrogenase 8 Oryza sativa subsp japonica (Rice) PR
Q8LNV6 CKX3 Cytokinin dehydrogenase 3 Oryza sativa subsp japonica (Rice) PR
Q6YW51 CKX6 Cytokinin dehydrogenase 6 Oryza sativa subsp japonica (Rice) PR
Q6YW50 CKX7 Cytokinin dehydrogenase 7 Oryza sativa subsp japonica (Rice) PR
Q94AX4 DLD D-lactate dehydrogenase [cytochrome], mitochondrial Arabidopsis thaliana (Mouse-ear cress) PR
Q9LY71 CKX6 Cytokinin dehydrogenase 6 Arabidopsis thaliana (Mouse-ear cress) PR
Q9FUJ2 CKX4 Cytokinin dehydrogenase 4 Arabidopsis thaliana (Mouse-ear cress) PR
10 20 30 40 50 60
MASYNLRSQV RLIAITIVII ITLSTPITTN TSPQPWNILS HNEFAGKLTS SSSSVESAAT
70 80 90 100 110 120
DFGHVTKIFP SAVLIPSSVE DITDLIKLSF DSQLSFPLAA RGHGHSHRGQ ASAKDGVVVN
130 140 150 160 170 180
MRSMVNRDRG IKVSRTCLYV DVDAAWLWIE VLNKTLELGL TPVSWTDYLY LTVGGTLSNG
190 200 210 220 230 240
GISGQTFRYG PQITNVLEMD VITGKGEIAT CSKDMNSDLF FAVLGGLGQF GIITRARIKL
250 260 270 280 290 300
EVAPKRAKWL RFLYIDFSEF TRDQERVISK TDGVDFLEGS IMVDHGPPDN WRSTYYPPSD
310 320 330 340 350 360
HLRIASMVKR HRVIYCLEVV KYYDETSQYT VNEEMEELSD SLNHVRGFMY EKDVTYMDFL
370 380 390 400 410 420
NRVRTGELNL KSKGQWDVPH PWLNLFVPKT QISKFDDGVF KGIILRNNIT SGPVLVYPMN
430 440 450 460 470 480
RNKWNDRMSA AIPEEDVFYA VGFLRSAGFD NWEAFDQENM EILKFCEDAN MGVIQYLPYH
490 500 510 520
SSQEGWVRHF GPRWNIFVER KYKYDPKMIL SPGQNIFQKI NSS