A3AVP1

PR
Gene name
CKX8 (Os04g0523500, LOC_Os04g44230, OsJ_15507, OSJNBb0065J09.8)
Protein name
Cytokinin dehydrogenase 8
Names
Cytokinin oxidase 8, OsCKX8
Species
Oryza sativa subsp japonica (Rice)
KEGG Pathway
osa:107275925
EC number
1.5.99.12: With other acceptors
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-126 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for A3AVP1

Entry ID Method Resolution Chain Position Source
AF-A3AVP1-F1 Predicted AlphaFoldDB

No variants for A3AVP1

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for A3AVP1

No associated diseases with A3AVP1

3 regional properties for A3AVP1

Type Name Position InterPro Accession
domain FAD linked oxidase, N-terminal 57 - 207 IPR006094
domain Cytokinin dehydrogenase 1, FAD/cytokinin binding domain 239 - 523 IPR015345
domain FAD-binding domain, PCMH-type 51 - 238 IPR016166

Functions

Description
EC Number 1.5.99.12 With other acceptors
Subcellular Localization
  • Secreted, extracellular space
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
extracellular space That part of a multicellular organism outside the cells proper, usually taken to be outside the plasma membranes, and occupied by fluid.

3 GO annotations of molecular function

Name Definition
cytokinin dehydrogenase activity Catalysis of the reaction: N6-dimethylallyladenine + acceptor + H2O = adenine + 3-methylbut-2-enal + reduced electron acceptor.
FAD binding Binding to the oxidized form, FAD, of flavin-adenine dinucleotide, the coenzyme or the prosthetic group of various flavoprotein oxidoreductase enzymes.
oxidoreductase activity Catalysis of an oxidation-reduction (redox) reaction, a reversible chemical reaction in which the oxidation state of an atom or atoms within a molecule is altered. One substrate acts as a hydrogen or electron donor and becomes oxidized, while the other acts as hydrogen or electron acceptor and becomes reduced.

1 GO annotations of biological process

Name Definition
cytokinin metabolic process The chemical reactions and pathways involving cytokinins, a class of adenine-derived compounds that can function in plants as growth regulators.

8 homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
Q5JLP4 CKX4 Cytokinin dehydrogenase 4 Oryza sativa subsp japonica (Rice) PR
Q6YW51 CKX6 Cytokinin dehydrogenase 6 Oryza sativa subsp japonica (Rice) PR
Q8LNV6 CKX3 Cytokinin dehydrogenase 3 Oryza sativa subsp japonica (Rice) PR
Q6YW50 CKX7 Cytokinin dehydrogenase 7 Oryza sativa subsp japonica (Rice) PR
Q9LY71 CKX6 Cytokinin dehydrogenase 6 Arabidopsis thaliana (Mouse-ear cress) PR
Q9FUJ2 CKX4 Cytokinin dehydrogenase 4 Arabidopsis thaliana (Mouse-ear cress) PR
Q94AX4 DLD D-lactate dehydrogenase [cytochrome], mitochondrial Arabidopsis thaliana (Mouse-ear cress) PR
Q9LTS3 CKX3 Cytokinin dehydrogenase 3 Arabidopsis thaliana (Mouse-ear cress) PR
10 20 30 40 50 60
MELKAMYLYA AVLAVLLCSS VNFIQSPTDV LGPVALLEPT PSSARDFGAV VSDAPFAVMR
70 80 90 100 110 120
PESPDDIALL LGALSSTAPS PRATVAAVGA GHSLHGQAQA RDGIVVETRA LPRDVHVVSA
130 140 150 160 170 180
RAHGGDDDAT VRAYADVGAG ALWVEVLEEC LKLGLAPPSW TDYLYLTVGG TLSNGGISGQ
190 200 210 220 230 240
TFKHGPQISN VLQLEVVTGK GEVVTCSPTE IPELFFAVLG GLGQFGIITR ARIPLQLAPP
250 260 270 280 290 300
KVRWVRAFYD SFETFTGDQE LLVSMPEQVD YVEGFMVLNE QSLHSSSVAF PAQLNFSPDF
310 320 330 340 350 360
GSKGRKKVYY CIEFAVHDFQ QDSSRADHVV KLVSAKLSYL RPHVYSVEVS YFDFLNRVRM
370 380 390 400 410 420
EEESLRSRGL WDVPHPWLNV FVPKHGITQF KGLLMDTVSA DDFEGPILVY PLLTDKWDGN
430 440 450 460 470 480
TSAVVPAAPD GVMYIFGVLR STDPARCGRA CVDSIMARHR RVADEACRDG GGGGRGIGAK
490 500 510 520 530
QYLARQPSPA RWRDHFGAGW GRFAARKARF DPLHVLGPGQ GIFPRTDSAG SM