Q9LRR7
PR
Gene name |
NCED3 |
Protein name |
9-cis-epoxycarotenoid dioxygenase NCED3, chloroplastic |
Names |
AtNCED3, Protein SALT TOLERANT 1 |
Species |
Arabidopsis thaliana (Mouse-ear cress) |
KEGG Pathway |
ath:AT3G14440 |
EC number |
1.13.11.51: With incorporation of two atoms of oxygen |
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q9LRR7
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q9LRR7-F1 | Predicted | AlphaFoldDB |
55 variants for Q9LRR7
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| ENSVATH10674365 | 6 | A>V | No | 1000Genomes | |
| ENSVATH10674334 | 10 | V>G | No | 1000Genomes | |
| tmp_3_4833446_G_A | 11 | S>F | No | 1000Genomes | |
| ENSVATH05829770 | 15 | L>F | No | 1000Genomes | |
| ENSVATH00323039 | 18 | N>D | No | 1000Genomes | |
| ENSVATH00323039 | 18 | N>H | No | 1000Genomes | |
| tmp_3_4833413_G_T | 22 | P>Q | No | 1000Genomes | |
| ENSVATH02144029 | 23 | P>S | No | 1000Genomes | |
| ENSVATH05829768 | 32 | L>F | No | 1000Genomes | |
| ENSVATH13917458 | 33 | S>T | No | 1000Genomes | |
| tmp_3_4833368_G_T | 37 | S>Y | No | 1000Genomes | |
| ENSVATH10674332 | 43 | R>P | No | 1000Genomes | |
| ENSVATH00323038 | 46 | R>C | No | 1000Genomes | |
| tmp_3_4833339_T_G | 47 | K>Q | No | 1000Genomes | |
| tmp_3_4833300_G_A | 60 | L>F | No | 1000Genomes | |
| ENSVATH05829766 | 81 | S>F | No | 1000Genomes | |
| ENSVATH05829765 | 83 | T>N | No | 1000Genomes | |
| ENSVATH05829764 | 84 | K>Q | No | 1000Genomes | |
| tmp_3_4833176_T_C | 101 | E>G | No | 1000Genomes | |
| tmp_3_4833128_G_A | 117 | A>V | No | 1000Genomes | |
| ENSVATH05829763 | 120 | S>I | No | 1000Genomes | |
| ENSVATH05829763 | 120 | S>T | No | 1000Genomes | |
| ENSVATH05829762 | 136 | R>Q | No | 1000Genomes | |
| tmp_3_4833060_G_A | 140 | P>S | No | 1000Genomes | |
| ENSVATH05829761 | 142 | V>A | No | 1000Genomes | |
| ENSVATH00323037 | 145 | L>I | No | 1000Genomes | |
| tmp_3_4833036_A_G | 148 | S>P | No | 1000Genomes | |
| tmp_3_4833029_T_C | 150 | K>R | No | 1000Genomes | |
| ENSVATH10674330 | 154 | V>L | No | 1000Genomes | |
| ENSVATH00323036 | 184 | H>D | No | 1000Genomes | |
| ENSVATH05829759 | 184 | H>R | No | 1000Genomes | |
| tmp_3_4832925_C_T | 185 | G>S | No | 1000Genomes | |
| tmp_3_4832916_T_C | 188 | S>G | No | 1000Genomes | |
| ENSVATH05829758 | 206 | G>D | No | 1000Genomes | |
| tmp_3_4832841_C_T | 213 | A>T | No | 1000Genomes | |
| ENSVATH00323032 | 271 | Q>R | No | 1000Genomes | |
| ENSVATH13917455 | 273 | T>A | No | 1000Genomes | |
| tmp_3_4832658_G_A | 274 | P>S | No | 1000Genomes | |
| tmp_3_4832643_T_G | 279 | K>Q | No | 1000Genomes | |
| ENSVATH05829755 | 287 | D>E | No | 1000Genomes | |
| tmp_3_4832562_C_T | 306 | E>K | No | 1000Genomes | |
| ENSVATH00323031 | 327 | P>R | No | 1000Genomes | |
| tmp_3_4832323_T_A | 385 | R>S | No | 1000Genomes | |
| ENSVATH05829751 | 395 | D>Y | No | 1000Genomes | |
| tmp_3_4832223_G_C | 419 | P>A | No | 1000Genomes | |
| tmp_3_4832157_A_T | 441 | S>T | No | 1000Genomes | |
| ENSVATH05829749 | 516 | E>K | No | 1000Genomes | |
| ENSVATH10674327 | 525 | N>K | No | 1000Genomes | |
| tmp_3_4831832_A_T | 549 | F>Y | No | 1000Genomes | |
| tmp_3_4831815_T_C | 555 | T>A | No | 1000Genomes | |
| tmp_3_4831794_T_A | 562 | I>L | No | 1000Genomes | |
| ENSVATH05829748 | 569 | E>D | No | 1000Genomes | |
| tmp_3_4831758_C_G | 574 | V>L | No | 1000Genomes | |
| tmp_3_4831694_G_A | 595 | A>V | No | 1000Genomes | |
| ENSVATH13917404 | 596 | K>N | No | 1000Genomes |
No associated diseases with Q9LRR7
Functions
| Description | ||
|---|---|---|
| EC Number | 1.13.11.51 | With incorporation of two atoms of oxygen |
| Subcellular Localization |
|
|
| PANTHER Family | ||
| PANTHER Subfamily | ||
| PANTHER Protein Class | ||
| PANTHER Pathway Category | No pathway information available | |
2 GO annotations of cellular component
| Name | Definition |
|---|---|
| chloroplast stroma | The space enclosed by the double membrane of a chloroplast but excluding the thylakoid space. It contains DNA, ribosomes and some temporary products of photosynthesis. |
| chloroplast thylakoid membrane | The pigmented membrane of a chloroplast thylakoid. An example of this component is found in Arabidopsis thaliana. |
3 GO annotations of molecular function
| Name | Definition |
|---|---|
| 9-cis-epoxycarotenoid dioxygenase activity | Catalysis of the reactions: a 9-cis-epoxycarotenoid + O2 = 2-cis,4-trans-xanthoxin + a 12'-apo-carotenal; 9-cis-violaxanthin + O2 = 2-cis,4-trans-xanthoxin + (3S,5R,6S)-5,6-epoxy-3-hydroxy-5,6-dihydro-12'-apo-beta-caroten-12'-al; and 9'-cis-neoxanthin + O2 = 2-cis,4-trans-xanthoxin + (3S,5R,6R)-5,6-dihydroxy-6,7-didehydro-5,6-dihydro-12'-apo-beta-caroten-12'-al. |
| carotenoid dioxygenase activity | Catalysis of the oxidative cleavage of carotenoids. |
| metal ion binding | Binding to a metal ion. |
5 GO annotations of biological process
| Name | Definition |
|---|---|
| abscisic acid biosynthetic process | The chemical reactions and pathways resulting in the formation of abscisic acid, 5-(1-hydroxy-2,6,6,trimethyl-4-oxocyclohex-2-en-1-y1)-3-methylpenta-2,4-dienoic acid. |
| carotene catabolic process | The chemical reactions and pathways resulting in the breakdown of carotenes, hydrocarbon carotenoids. |
| hyperosmotic salinity response | Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of detection of, or exposure to, an increase in the concentration of salt (particularly but not exclusively sodium and chloride ions) in the environment. |
| response to osmotic stress | Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating an increase or decrease in the concentration of solutes outside the organism or cell. |
| response to water deprivation | Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a water deprivation stimulus, prolonged deprivation of water. |
9 homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| Q28175 | RPE65 | Retinoid isomerohydrolase | Bos taurus (Bovine) | PR |
| Q9YGX2 | RPE65 | Retinoid isomerohydrolase | Gallus gallus (Chicken) | PR |
| Q16518 | RPE65 | Retinoid isomerohydrolase | Homo sapiens (Human) | PR |
| O24592 | VP14 | 9-cis-epoxycarotenoid dioxygenase 1, chloroplastic | Zea mays (Maize) | PR |
| Q91ZQ5 | Rpe65 | Retinoid isomerohydrolase | Mus musculus (Mouse) | PR |
| O70276 | Rpe65 | Retinoid isomerohydrolase | Rattus norvegicus (Rat) | PR |
| Q8LIY8 | CCD8B | Carotenoid cleavage dioxygenase 8 homolog B, chloroplastic | Oryza sativa subsp japonica (Rice) | PR |
| Q9C6Z1 | NCED5 | Probable 9-cis-epoxycarotenoid dioxygenase NCED5, chloroplastic | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q9LRM7 | NCED6 | 9-cis-epoxycarotenoid dioxygenase NCED6, chloroplastic | Arabidopsis thaliana (Mouse-ear cress) | PR |
| 10 | 20 | 30 | 40 | 50 | 60 |
| MASFTATAAV | SGRWLGGNHT | QPPLSSSQSS | DLSYCSSLPM | ASRVTRKLNV | SSALHTPPAL |
| 70 | 80 | 90 | 100 | 110 | 120 |
| HFPKQSSNSP | AIVVKPKAKE | SNTKQMNLFQ | RAAAAALDAA | EGFLVSHEKL | HPLPKTADPS |
| 130 | 140 | 150 | 160 | 170 | 180 |
| VQIAGNFAPV | NEQPVRRNLP | VVGKLPDSIK | GVYVRNGANP | LHEPVTGHHF | FDGDGMVHAV |
| 190 | 200 | 210 | 220 | 230 | 240 |
| KFEHGSASYA | CRFTQTNRFV | QERQLGRPVF | PKAIGELHGH | TGIARLMLFY | ARAAAGIVDP |
| 250 | 260 | 270 | 280 | 290 | 300 |
| AHGTGVANAG | LVYFNGRLLA | MSEDDLPYQV | QITPNGDLKT | VGRFDFDGQL | ESTMIAHPKV |
| 310 | 320 | 330 | 340 | 350 | 360 |
| DPESGELFAL | SYDVVSKPYL | KYFRFSPDGT | KSPDVEIQLD | QPTMMHDFAI | TENFVVVPDQ |
| 370 | 380 | 390 | 400 | 410 | 420 |
| QVVFKLPEMI | RGGSPVVYDK | NKVARFGILD | KYAEDSSNIK | WIDAPDCFCF | HLWNAWEEPE |
| 430 | 440 | 450 | 460 | 470 | 480 |
| TDEVVVIGSC | MTPPDSIFNE | SDENLKSVLS | EIRLNLKTGE | STRRPIISNE | DQQVNLEAGM |
| 490 | 500 | 510 | 520 | 530 | 540 |
| VNRNMLGRKT | KFAYLALAEP | WPKVSGFAKV | DLTTGEVKKH | LYGDNRYGGE | PLFLPGEGGE |
| 550 | 560 | 570 | 580 | 590 | |
| EDEGYILCFV | HDEKTWKSEL | QIVNAVSLEV | EATVKLPSRV | PYGFHGTFIG | ADDLAKQVV |