Q9LRP3
Gene name |
At3g17420 (MTO12.1) |
Protein name |
Probable receptor-like protein kinase At3g17420 |
Names |
|
Species |
Arabidopsis thaliana (Mouse-ear cress) |
KEGG Pathway |
ath:AT3G17420 |
EC number |
2.7.11.1: Protein-serine/threonine kinases |
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
297-321 (Activation loop from InterPro)
Target domain |
154-433 (Protein kinase domain) |
Relief mechanism |
|
Assay |
|
Autoinhibited structure
Activated structure
1 structures for Q9LRP3
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q9LRP3-F1 | Predicted | AlphaFoldDB |
14 variants for Q9LRP3
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| tmp_3_5961294_C_T | 7 | R>Q | No | 1000Genomes | |
| ENSVATH05850697 | 15 | V>I | No | 1000Genomes | |
| tmp_3_5961255_T_C | 20 | E>G | No | 1000Genomes | |
| ENSVATH13936451 | 64 | E>V | No | 1000Genomes | |
| ENSVATH05850696 | 68 | E>D | No | 1000Genomes | |
| ENSVATH05850695 | 81 | T>N | No | 1000Genomes | |
| tmp_3_5961058_G_A | 86 | L>F | No | 1000Genomes | |
| ENSVATH05850694 | 135 | H>N | No | 1000Genomes | |
| tmp_3_5960859_T_C | 152 | N>S | No | 1000Genomes | |
| tmp_3_5960815_C_T | 167 | V>I | No | 1000Genomes | |
| tmp_3_5960220_G_A | 309 | S>L | No | 1000Genomes | |
| ENSVATH02156323 | 374 | M>I | No | 1000Genomes | |
| ENSVATH02156322 | 377 | Q>E | No | 1000Genomes | |
| tmp_3_5959777_G_T | 394 | T>K | No | 1000Genomes |
No associated diseases with Q9LRP3
Functions
| Description | ||
|---|---|---|
| EC Number | 2.7.11.1 | Protein-serine/threonine kinases |
| Subcellular Localization |
|
|
| PANTHER Family | ||
| PANTHER Subfamily | ||
| PANTHER Protein Class | ||
| PANTHER Pathway Category | No pathway information available | |
4 GO annotations of cellular component
| Name | Definition |
|---|---|
| glyoxysome | A specialized form of peroxisome that contains the enzymes of the glyoxylate pathway. The glyoxysome is found in some plant cells, notably the cells of germinating seeds. |
| integral component of membrane | The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane. |
| plasma membrane | The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins. |
| plasmodesma | A fine cytoplasmic channel, found in all higher plants, that connects the cytoplasm of one cell to that of an adjacent cell. |
3 GO annotations of molecular function
| Name | Definition |
|---|---|
| ATP binding | Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator. |
| protein serine kinase activity | Catalysis of the reactions: ATP + protein serine = ADP + protein serine phosphate. |
| protein serine/threonine kinase activity | Catalysis of the reactions: ATP + protein serine = ADP + protein serine phosphate, and ATP + protein threonine = ADP + protein threonine phosphate. |
1 GO annotations of biological process
| Name | Definition |
|---|---|
| protein phosphorylation | The process of introducing a phosphate group on to a protein. |
55 homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| P08630 | Btk | Tyrosine-protein kinase Btk | Drosophila melanogaster (Fruit fly) | SS |
| Q9Y616 | IRAK3 | Interleukin-1 receptor-associated kinase 3 | Homo sapiens (Human) | PR |
| P53667 | LIMK1 | LIM domain kinase 1 | Homo sapiens (Human) | PR |
| P53671 | LIMK2 | LIM domain kinase 2 | Homo sapiens (Human) | PR |
| Q8K4B2 | Irak3 | Interleukin-1 receptor-associated kinase 3 | Mus musculus (Mouse) | PR |
| Q8CFA1 | Irak2 | Interleukin-1 receptor-associated kinase-like 2 | Mus musculus (Mouse) | PR |
| O54785 | Limk2 | LIM domain kinase 2 | Mus musculus (Mouse) | PR |
| P55144 | Tyro3 | Tyrosine-protein kinase receptor TYRO3 | Mus musculus (Mouse) | SS |
| Q61006 | Musk | Muscle, skeletal receptor tyrosine-protein kinase | Mus musculus (Mouse) | SS |
| Q00993 | Axl | Tyrosine-protein kinase receptor UFO | Mus musculus (Mouse) | PR |
| Q60805 | Mertk | Tyrosine-protein kinase Mer | Mus musculus (Mouse) | SS |
| Q3UFB7 | Ntrk1 | High affinity nerve growth factor receptor | Mus musculus (Mouse) | SS |
| P09581 | Csf1r | Macrophage colony-stimulating factor 1 receptor | Mus musculus (Mouse) | SS |
| P21803 | Fgfr2 | Fibroblast growth factor receptor 2 | Mus musculus (Mouse) | SS |
| P16092 | Fgfr1 | Fibroblast growth factor receptor 1 | Mus musculus (Mouse) | SS |
| Q03142 | Fgfr4 | Fibroblast growth factor receptor 4 | Mus musculus (Mouse) | PR |
| P05622 | Pdgfrb | Platelet-derived growth factor receptor beta | Mus musculus (Mouse) | SS |
| Q00342 | Flt3 | Receptor-type tyrosine-protein kinase FLT3 | Mus musculus (Mouse) | SS |
| Q61851 | Fgfr3 | Fibroblast growth factor receptor 3 | Mus musculus (Mouse) | PR |
| Q4QQS0 | Irak2 | Interleukin-1 receptor-associated kinase-like 2 | Rattus norvegicus (Rat) | PR |
| Q9ASQ5 | CRCK3 | Calmodulin-binding receptor-like cytoplasmic kinase 3 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q9LSV3 | WAKL16 | Putative wall-associated receptor kinase-like 16 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q9STF0 | LECRKS3 | Receptor like protein kinase S.3 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q9SCZ4 | FER | Receptor-like protein kinase FERONIA | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q9M342 | WAKL15 | Wall-associated receptor kinase-like 15 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q9LYN6 | At3g56050 | Probable inactive receptor-like protein kinase At3g56050 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q8VZJ9 | CRCK2 | Calmodulin-binding receptor-like cytoplasmic kinase 2 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q0WNY5 | WAKL18 | Wall-associated receptor kinase-like 18 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q94C25 | At5g20050 | Probable receptor-like protein kinase At5g20050 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q9FLW0 | At5g24010 | Probable receptor-like protein kinase At5g24010 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q9LTC0 | PBL19 | Probable serine/threonine-protein kinase PBL19 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q9FIL7 | CRCK1 | Calmodulin-binding receptor-like cytoplasmic kinase 1 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| P43293 | PBL11 | Probable serine/threonine-protein kinase PBL11 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q3E8W4 | ANX2 | Receptor-like protein kinase ANXUR2 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q8LPS5 | SERK5 | Somatic embryogenesis receptor kinase 5 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q9FN94 | At5g59670 | Receptor-like protein kinase At5g59670 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| P93050 | BSH | Probable LRR receptor-like serine/threonine-protein kinase RKF3 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q8RWW0 | ALE2 | Receptor-like serine/threonine-protein kinase ALE2 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q9LPZ9 | SD113 | G-type lectin S-receptor-like serine/threonine-protein kinase SD1-13 | Arabidopsis thaliana (Mouse-ear cress) | SS |
| C0LGG3 | At1g51820 | Probable LRR receptor-like serine/threonine-protein kinase At1g51820 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| P43298 | TMK1 | Receptor protein kinase TMK1 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| C0LGI2 | At1g67720 | Probable LRR receptor-like serine/threonine-protein kinase At1g67720 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q9ZQR3 | At2g14510 | Leucine-rich repeat receptor-like serine/threonine-protein kinase At2g14510 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q9LIG2 | At3g21340 | Receptor-like protein kinase At3g21340 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q9SNA3 | At3g46340 | Putative receptor-like protein kinase At3g46340 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q9M2S4 | LECRKS4 | L-type lectin-domain containing receptor kinase S.4 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q8RWZ5 | SD25 | G-type lectin S-receptor-like serine/threonine-protein kinase SD2-5 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| C0LGW2 | PAM74 | Probable LRR receptor-like serine/threonine-protein kinase PAM74 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q9FN93 | At5g59680 | Probable LRR receptor-like serine/threonine-protein kinase At5g59680 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q9SXB4 | At1g11300 | G-type lectin S-receptor-like serine/threonine-protein kinase At1g11300 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q84JQ4 | PRK2 | Pollen receptor-like kinase 2 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q93ZS4 | NIK3 | Protein NSP-INTERACTING KINASE 3 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q94AG2 | SERK1 | Somatic embryogenesis receptor kinase 1 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| O64477 | At2g19130 | G-type lectin S-receptor-like serine/threonine-protein kinase At2g19130 | Arabidopsis thaliana (Mouse-ear cress) | SS |
| Q9XIC7 | SERK2 | Somatic embryogenesis receptor kinase 2 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| 10 | 20 | 30 | 40 | 50 | 60 |
| MTSQLKRTLT | KRYGVLELWE | IIVIALFAAF | IVILVLSVWL | SFRKKSKRSN | ATTLPVTQSP |
| 70 | 80 | 90 | 100 | 110 | 120 |
| RFTEEIKEIS | VDHGSSNNNG | TSYQTLDEKF | VEDIENGDKF | SGSLEKKPLV | GSHLPPSTPS |
| 130 | 140 | 150 | 160 | 170 | 180 |
| TTAPSPLLGL | PEVSHIGWGH | WFTLRDLQLA | TNHFSKESII | GDGGYGVVYH | GTLTNKTPVA |
| 190 | 200 | 210 | 220 | 230 | 240 |
| VKKLLNNPGQ | ADKDFRVEVE | AIGHVRHKNL | VRLLGYCVEG | THRMLVYEYM | NNGNLEQWLH |
| 250 | 260 | 270 | 280 | 290 | 300 |
| GDMIHKGHLT | WEARIKVLVG | TAKALAYLHE | AIEPKVVHRD | IKSSNILMDD | NFDAKLSDFG |
| 310 | 320 | 330 | 340 | 350 | 360 |
| LAKLLGADSN | YVSTRVMGTF | GYVAPEYANS | GLLNEKSDVY | SYGVVLLEAI | TGRYPVDYAR |
| 370 | 380 | 390 | 400 | 410 | 420 |
| PKEEVHMVEW | LKLMVQQKQF | EEVVDKELEI | KPTTSELKRA | LLTALRCVDP | DADKRPKMSQ |
| 430 | 440 | 450 | 460 | ||
| VARMLESDEY | PVMPREERRR | RRNQNAETHR | ESTDTNKDND | ITTDAKI |