Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

Autoinhibited structure

Activated structure

1 structures for Q9LMK7

Entry ID Method Resolution Chain Position Source
AF-Q9LMK7-F1 Predicted AlphaFoldDB

10 variants for Q9LMK7

Variant ID(s) Position Change Description Diseaes Association Provenance
tmp_1_2193668_C_G 7 E>D No 1000Genomes
tmp_1_2193577_C_T 38 A>T No 1000Genomes
ENSVATH01020478 129 G>A No 1000Genomes
ENSVATH01020478 129 G>V No 1000Genomes
ENSVATH10723719 165 E>K No 1000Genomes
ENSVATH01020475 169 A>S No 1000Genomes
ENSVATH01020475 169 A>T No 1000Genomes
tmp_1_2192512_A_C 179 L>V No 1000Genomes
tmp_1_2192491_T_A 186 T>S No 1000Genomes
tmp_1_2192416_C_T 211 E>K No 1000Genomes

No associated diseases with Q9LMK7

2 regional properties for Q9LMK7

Type Name Position InterPro Accession
domain Ran binding domain 27 - 162 IPR000156
domain Ran-specific GTPase-activating protein 1, Ran-binding domain 25 - 155 IPR045256

Functions

Description
EC Number
Subcellular Localization
  • Nucleus, nuclear pore complex
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

4 GO annotations of cellular component

Name Definition
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
cytosol The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
extracellular region The space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane. This term covers the host cell environment outside an intracellular parasite.
nuclear pore A protein complex providing a discrete opening in the nuclear envelope of a eukaryotic cell, where the inner and outer nuclear membranes are joined.

No GO annotations of molecular function

Name Definition
No GO annotations for molecular function

4 GO annotations of biological process

Name Definition
mRNA transport The directed movement of mRNA, messenger ribonucleic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
nucleocytoplasmic transport The directed movement of molecules between the nucleus and the cytoplasm.
protein transport The directed movement of proteins into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
regulation of catalytic activity Any process that modulates the activity of an enzyme.

6 homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
Q3T0M7 RANBP1 Ran-specific GTPase-activating protein Bos taurus (Bovine) PR
Q86VV4 RANBP3L Ran-binding protein 3-like Homo sapiens (Human) PR
P43487 RANBP1 Ran-specific GTPase-activating protein Homo sapiens (Human) PR
P34022 Ranbp1 Ran-specific GTPase-activating protein Mus musculus (Mouse) PR
P92985 POX1 Ran-binding protein 1 homolog c Arabidopsis thaliana (Mouse-ear cress) PR
Q8RWG8 RANBP1B Ran-binding protein 1 homolog b Arabidopsis thaliana (Mouse-ear cress) PR
10 20 30 40 50 60
MATNEPEHEH RDEEEAGANE DEDTGAQVAP IVRLEEVAVT TGEEDEDAVL DLKSKLYRFD
70 80 90 100 110 120
KDANQWKERG AGTVKFLKHK NTGKIRLVMR QSKTLKICAN HFVKSGMSVQ EHVGNEKSCV
130 140 150 160 170 180
WHARDFADGE LKDELFCIRF ASIENCKTFM QKFKEVAESE EEKEESKDAA DTAGLLEKLT
190 200 210 220
VEETKTEEKT EAKAVETAKT EVKAEEKKES EAEKSGEAKK TEESGPST