Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

Autoinhibited structure

Activated structure

1 structures for Q9LLY4

Entry ID Method Resolution Chain Position Source
AF-Q9LLY4-F1 Predicted AlphaFoldDB

No variants for Q9LLY4

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q9LLY4

No associated diseases with Q9LLY4

8 regional properties for Q9LLY4

Type Name Position InterPro Accession
domain THIF-type NAD/FAD binding fold 55 - 445 IPR000594-1
domain THIF-type NAD/FAD binding fold 451 - 949 IPR000594-2
conserved_site Ubiquitin-activating enzyme E1, conserved site 411 - 419 IPR018074
domain Ubiquitin-activating enzyme E1, C-terminal 922 - 1053 IPR018965
domain Ubiquitin-activating enzyme, SCCH domain 638 - 884 IPR019572
domain Ubiquitin-activating enzyme E1, FCCH domain 227 - 296 IPR032418
domain Ubiquitin-activating enzyme E1, four-helix bundle 298 - 366 IPR032420
active_site Ubiquitin-activating enzyme E1, Cys active site 630 - 638 IPR033127

Functions

Description
EC Number 2.3.1.51 Transferring groups other than amino-acyl groups
Subcellular Localization
  • Plastid, chloroplast membrane ; Multi-pass membrane protein
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

2 GO annotations of cellular component

Name Definition
chloroplast membrane Either of the lipid bilayers that surround a chloroplast and form the chloroplast envelope.
integral component of membrane The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.

1 GO annotations of molecular function

Name Definition
1-acylglycerol-3-phosphate O-acyltransferase activity Catalysis of the reaction: acyl-CoA + 1-acyl-sn-glycerol-3-phosphate = CoA + 1,2-diacyl-sn-glycerol-3-phosphate.

2 GO annotations of biological process

Name Definition
CDP-diacylglycerol biosynthetic process The chemical reactions and pathways resulting in the formation of CDP-diacylglycerol, CDP-1,2-diacylglycerol, a substance composed of diacylglycerol in glycosidic linkage with cytidine diphosphate.
phosphatidic acid biosynthetic process The chemical reactions and pathways resulting in the formation of phosphatidic acid, any derivative of glycerol phosphate in which both the remaining hydroxyl groups of the glycerol moiety are esterified with fatty acids.

6 homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
P33333 SLC1 1-acyl-sn-glycerol-3-phosphate acyltransferase Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) PR
Q95JH2 AGPAT1 1-acyl-sn-glycerol-3-phosphate acyltransferase alpha Bos taurus (Bovine) PR
Q99943 AGPAT1 1-acyl-sn-glycerol-3-phosphate acyltransferase alpha Homo sapiens (Human) PR
O15120 AGPAT2 1-acyl-sn-glycerol-3-phosphate acyltransferase beta Homo sapiens (Human) PR
Q8K3K7 Agpat2 1-acyl-sn-glycerol-3-phosphate acyltransferase beta Mus musculus (Mouse) PR
Q8GXU8 LPAT1 1-acyl-sn-glycerol-3-phosphate acyltransferase LPAT1, chloroplastic Arabidopsis thaliana (Mouse-ear cress) PR
10 20 30 40 50 60
MDVASAPGVS SHPPYYSKPI CSSQSSLIRI PINKGCCFAR SSNLITSLHA ASRGVTRRTS
70 80 90 100 110 120
GVQWCYRSIR FDPFKVNDKN SRTVTVRSDL SGAATPESTY PEPEIKLSSR LRGICFCLVA
130 140 150 160 170 180
GVSAIVLIVL MITGHPFVLL FDRYRRKFHH FIAKLWASIS IYPFYKTDIQ GLENLPSSDT
190 200 210 220 230 240
PCVYVSNHQS FLDIYTLLSL GQSYKFISKT GIFVIPVIGW AMSMMGVVPL KRMDPRSQVD
250 260 270 280 290 300
CLKRCMELVK KGASVFFFPE GTRSKDGRLG PFKKGAFTIA AKTGVPVVPI TLMGTGKIMP
310 320 330 340
TGSEGILNHG DVRVIIHKPI YGSKADLLCD EARNKIAESM NLVS