Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

Autoinhibited structure

Activated structure

1 structures for Q9LKR7

Entry ID Method Resolution Chain Position Source
AF-Q9LKR7-F1 Predicted AlphaFoldDB

69 variants for Q9LKR7

Variant ID(s) Position Change Description Diseaes Association Provenance
ENSVATH11300686 3 L>V No 1000Genomes
ENSVATH11300643 15 W>R No 1000Genomes
tmp_5_10483935_C_G 30 V>L No 1000Genomes
ENSVATH07097130 34 K>E No 1000Genomes
tmp_5_10483889_G_C 45 P>R No 1000Genomes
tmp_5_10483736_C_T 63 V>M No 1000Genomes
ENSVATH07097128 79 K>I No 1000Genomes
tmp_5_10483187_C_T 122 R>K No 1000Genomes
ENSVATH03164302 129 E>G No 1000Genomes
ENSVATH09483071 130 E>D No 1000Genomes
tmp_5_10483048_C_T 132 G>R No 1000Genomes
tmp_5_10483035_G_A 136 S>F No 1000Genomes
tmp_5_10482875_A_G 154 I>T No 1000Genomes
tmp_5_10482872_G_A 155 P>L No 1000Genomes
ENSVATH00659758 158 T>A No 1000Genomes
ENSVATH07097109 180 I>V No 1000Genomes
ENSVATH07097105 185 R>G No 1000Genomes
ENSVATH07097104 191 V>I No 1000Genomes
ENSVATH14328155 196 G>S No 1000Genomes
tmp_5_10482550_C_T 199 V>I No 1000Genomes
tmp_5_10482477_G_T 223 P>H No 1000Genomes
ENSVATH07097103 224 G>R No 1000Genomes
tmp_5_10482465_G_A 227 S>F No 1000Genomes
tmp_5_10482457_C_T 230 A>T No 1000Genomes
tmp_5_10482418_G_C 243 R>G No 1000Genomes
tmp_5_10482393_A_C 251 V>G No 1000Genomes
tmp_5_10482390_C_T 252 S>N No 1000Genomes
ENSVATH11300433 255 L>F No 1000Genomes
tmp_5_10482358_C_T 263 V>I No 1000Genomes
ENSVATH07097101 270 E>G No 1000Genomes
ENSVATH11300432 271 K>N No 1000Genomes
tmp_5_10482188_T_G 292 K>N No 1000Genomes
ENSVATH00659750 296 S>G No 1000Genomes
tmp_5_10482176_A_C 296 S>R No 1000Genomes
tmp_5_10482171_G_A 298 A>V No 1000Genomes
ENSVATH00659749 301 D>E No 1000Genomes
tmp_5_10482160_G_A 302 R>C No 1000Genomes
tmp_5_10482151_C_T 305 D>N No 1000Genomes
ENSVATH14328023 311 H>D No 1000Genomes
tmp_5_10482052_G_A 314 T>I No 1000Genomes
ENSVATH03164284 327 I>N No 1000Genomes
tmp_5_10481983_G_C 337 T>S No 1000Genomes
ENSVATH03164282 341 A>G No 1000Genomes
ENSVATH03164281 343 L>F No 1000Genomes
ENSVATH03164277 363 L>W No 1000Genomes
tmp_5_10481902_T_C 364 E>G No 1000Genomes
ENSVATH00659746 380 E>G No 1000Genomes
ENSVATH07097095 382 K>I No 1000Genomes
ENSVATH03164269 388 N>D No 1000Genomes
tmp_5_10481609_G_T 401 P>T No 1000Genomes
ENSVATH03164261 405 T>K No 1000Genomes
ENSVATH07097093 416 D>N No 1000Genomes
ENSVATH07097091 433 N>K No 1000Genomes
ENSVATH07097090 436 E>K No 1000Genomes
ENSVATH00659743 441 E>K No 1000Genomes
ENSVATH11300303 457 L>I No 1000Genomes
ENSVATH03164250 458 W>L No 1000Genomes
ENSVATH03164249 460 M>L No 1000Genomes
ENSVATH00659742 462 K>E No 1000Genomes
ENSVATH11300301 471 V>F No 1000Genomes
ENSVATH11300301 471 V>I No 1000Genomes
tmp_5_10481201_T_A 481 D>V No 1000Genomes
ENSVATH03164242 502 N>K No 1000Genomes
tmp_5_10481133_G_A 504 L>F No 1000Genomes
ENSVATH00659738 515 Y>F No 1000Genomes
tmp_5_10481081_T_A 521 E>V No 1000Genomes
ENSVATH07097087 522 G>R No 1000Genomes
tmp_5_10481072_C_G 524 R>P No 1000Genomes
ENSVATH03164241 528 I>L No 1000Genomes

No associated diseases with Q9LKR7

2 regional properties for Q9LKR7

Type Name Position InterPro Accession
conserved_site Sugar transporter, conserved site 160 - 176 IPR005829
domain Major facilitator superfamily domain 88 - 514 IPR020846

Functions

Description
EC Number 3.2.1.21 Glycosidases, ie enzymes hydrolyzing O- and S-glycosyl compounds
Subcellular Localization
  • Endoplasmic reticulum lumen
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

2 GO annotations of cellular component

Name Definition
endoplasmic reticulum lumen The volume enclosed by the membranes of the endoplasmic reticulum.
plastid Any member of a family of organelles found in the cytoplasm of plants and some protists, which are membrane-bounded and contain DNA. Plant plastids develop from a common type, the proplastid.

2 GO annotations of molecular function

Name Definition
beta-glucosidase activity Catalysis of the hydrolysis of terminal, non-reducing beta-D-glucose residues with release of beta-D-glucose.
scopolin beta-glucosidase activity Catalysis of the reaction: H2O + scopolin <=> beta-D-glucose + scopoletin.

3 GO annotations of biological process

Name Definition
carbohydrate metabolic process The chemical reactions and pathways involving carbohydrates, any of a group of organic compounds based of the general formula Cx(H2O)y.
glucosinolate catabolic process The chemical reactions and pathways resulting in the breakdown of glucosinolates, substituted thioglucosides found in rapeseed products and related cruciferae.
response to salt stress Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating an increase or decrease in the concentration of salt (particularly but not exclusively sodium and chloride ions) in the environment.

5 homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
P11988 bglB 6-phospho-beta-glucosidase BglB Escherichia coli (strain K12) PR
Q46829 bglA 6-phospho-beta-glucosidase BglA Escherichia coli (strain K12) PR
O64879 BGLU15 Beta-glucosidase 15 Arabidopsis thaliana (Mouse-ear cress) PR
Q3E8E5 TGG3 Putative myrosinase 3 Arabidopsis thaliana (Mouse-ear cress) PR
Q8GXT2 BGLU29 Beta-glucosidase 29 Arabidopsis thaliana (Mouse-ear cress) PR
10 20 30 40 50 60
MVLQKLPLMS IGLLWLLIIV GPLVNADGPV CPPKPSDKLS RAHFPKGFLF GTATAAYQVE
70 80 90 100 110 120
GAVNETCRGP SVWDIYCKKY PEKCNGDNGT QAVDFFYRYK EDIQLMKNLN TDSFRLSISW
130 140 150 160 170 180
TRIFPHGREE NGVSKSGVQF YHDLIDELKR NGIIPFVTVF HWDTPQTLEN EYGGFLSAHI
190 200 210 220 230 240
VKDFREYAEF VFKEYGGKVK HWITFNEPWV FAHAGYDVGK KAPGRCSPYA KDETVKGDCL
250 260 270 280 290 300
GGRSGYEAYL VSHNLLNAHA EAVEAFRQCE KCKGGKIGIA HSPAWFEPHD FKDEQSGATI
310 320 330 340 350 360
DRALDFIMGW HLDTTMFGDY PQTMKDIVGH RLPKFTTEQI AKLKNSADFV GINYYTSTFS
370 380 390 400 410 420
KHLEKPNHAE PKFKQDSLVE WKNKNVNNIT IGSKPETGPL PVYSTGFRKV LKYVKDKYAN
430 440 450 460 470 480
PEIIIMENGY GENLKENDSV ENGTADYNRE SYLKKHLWSM HKAICEDKVN VTGYFVWSLM
490 500 510 520 530
DNFEWQDGFK NRFGLYYIDY KNNLTRHEKV SGKYYREFLS EGVRPSAIKK DEL