Q46829

PR
Gene name
bglA (bglD, yqfC, b2901, JW2869)
Protein name
6-phospho-beta-glucosidase BglA
Names
Phospho-beta-glucosidase A
Species
Escherichia coli (strain K12)
KEGG Pathway
eco:b2901
EC number
3.2.1.86: Glycosidases, ie enzymes hydrolyzing O- and S-glycosyl compounds
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

424-479 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

2 structures for Q46829

Entry ID Method Resolution Chain Position Source
2XHY X-ray 230 A A/B/C/D 1-479 PDB
AF-Q46829-F1 Predicted AlphaFoldDB

No variants for Q46829

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q46829

No associated diseases with Q46829

5 regional properties for Q46829

Type Name Position InterPro Accession
domain SNF2, N-terminal 1471 - 1766 IPR000330
domain Helicase, C-terminal 1805 - 1976 IPR001650
domain Helicase superfamily 1/2, ATP-binding domain 1447 - 1644 IPR014001
domain Mot1, central domain 782 - 1239 IPR022707
domain Mot1, ATP-binding domain 1451 - 1683 IPR044078

Functions

Description
EC Number 3.2.1.86 Glycosidases, ie enzymes hydrolyzing O- and S-glycosyl compounds
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
cytosol The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.

4 GO annotations of molecular function

Name Definition
6-phospho-beta-glucosidase activity Catalysis of the reaction: 6-phospho-beta-D-glucoside-(1,4)-D-glucose + H2O = D-glucose 6-phosphate + glucose.
beta-glucosidase activity Catalysis of the hydrolysis of terminal, non-reducing beta-D-glucose residues with release of beta-D-glucose.
glucosidase activity Catalysis of the hydrolysis of glucosyl compounds, substances containing a group derived from a cyclic form of glucose or a glucose derivative.
methyl beta-D-glucoside 6-phosphate glucohydrolase activity Catalysis of the reaction: methyl beta-D-glucoside 6-phosphate + H2O = beta-D-glucose 6-phosphate + methanol.

1 GO annotations of biological process

Name Definition
carbohydrate catabolic process The chemical reactions and pathways resulting in the breakdown of carbohydrates, any of a group of organic compounds based of the general formula Cx(H2O)y.

4 homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
Q3E8E5 TGG3 Putative myrosinase 3 Arabidopsis thaliana (Mouse-ear cress) PR
O64879 BGLU15 Beta-glucosidase 15 Arabidopsis thaliana (Mouse-ear cress) PR
Q8GXT2 BGLU29 Beta-glucosidase 29 Arabidopsis thaliana (Mouse-ear cress) PR
Q9LKR7 BGLU24 Beta-glucosidase 24 Arabidopsis thaliana (Mouse-ear cress) PR
10 20 30 40 50 60
MIVKKLTLPK DFLWGGAVAA HQVEGGWNKG GKGPSICDVL TGGAHGVPRE ITKEVLPGKY
70 80 90 100 110 120
YPNHEAVDFY GHYKEDIKLF AEMGFKCFRT SIAWTRIFPK GDEAQPNEEG LKFYDDMFDE
130 140 150 160 170 180
LLKYNIEPVI TLSHFEMPLH LVQQYGSWTN RKVVDFFVRF AEVVFERYKH KVKYWMTFNE
190 200 210 220 230 240
INNQRNWRAP LFGYCCSGVV YTEHENPEET MYQVLHHQFV ASALAVKAAR RINPEMKVGC
250 260 270 280 290 300
MLAMVPLYPY SCNPDDVMFA QESMRERYVF TDVQLRGYYP SYVLNEWERR GFNIKMEDGD
310 320 330 340 350 360
LDVLREGTCD YLGFSYYMTN AVKAEGGTGD AISGFEGSVP NPYVKASDWG WQIDPVGLRY
370 380 390 400 410 420
ALCELYERYQ RPLFIVENGF GAYDKVEEDG SINDDYRIDY LRAHIEEMKK AVTYDGVDLM
430 440 450 460 470
GYTPWGCIDC VSFTTGQYSK RYGFIYVNKH DDGTGDMSRS RKKSFNWYKE VIASNGEKL