O64879
PR
Gene name |
BGLU15 |
Protein name |
Beta-glucosidase 15 |
Names |
AtBGLU15 |
Species |
Arabidopsis thaliana (Mouse-ear cress) |
KEGG Pathway |
ath:AT2G44450 |
EC number |
3.2.1.21: Glycosidases, ie enzymes hydrolyzing O- and S-glycosyl compounds |
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for O64879
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-O64879-F1 | Predicted | AlphaFoldDB |
32 variants for O64879
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| ENSVATH14614566 | 2 | R>T | No | 1000Genomes | |
| ENSVATH14614567 | 14 | V>A | No | 1000Genomes | |
| ENSVATH05715758 | 19 | D>E | No | 1000Genomes | |
| ENSVATH05715759 | 28 | T>A | No | 1000Genomes | |
| tmp_2_18341053_A_C | 30 | K>Q | No | 1000Genomes | |
| ENSVATH01987482 | 30 | K>R | No | 1000Genomes | |
| ENSVATH13636375 | 35 | D>A | No | 1000Genomes | |
| tmp_2_18341090_T_A | 42 | F>Y | No | 1000Genomes | |
| tmp_2_18341101_A_G | 46 | T>A | No | 1000Genomes | |
| tmp_2_18341235_C_G | 62 | P>R | No | 1000Genomes | |
| tmp_2_18341234_C_A | 62 | P>T | No | 1000Genomes | |
| tmp_2_18341249_A_G | 67 | T>A | No | 1000Genomes | |
| ENSVATH01987495 | 122 | L>R | No | 1000Genomes | |
| tmp_2_18341898_A_T | 139 | N>Y | No | 1000Genomes | |
| tmp_2_18342170_C_A | 160 | A>D | No | 1000Genomes | |
| ENSVATH13636434 | 160 | A>S | No | 1000Genomes | |
| ENSVATH13636434 | 160 | A>T | No | 1000Genomes | |
| ENSVATH00274700 | 172 | E>D | No | 1000Genomes | |
| ENSVATH05715791 | 234 | T>S | No | 1000Genomes | |
| tmp_2_18342518_C_T | 250 | A>V | No | 1000Genomes | |
| ENSVATH13636458 | 253 | V>I | No | 1000Genomes | |
| ENSVATH13636459 | 256 | E>A | No | 1000Genomes | |
| tmp_2_18342541_T_C | 258 | Y>H | No | 1000Genomes | |
| tmp_2_18342701_T_C | 278 | Y>H | No | 1000Genomes | |
| ENSVATH05715796 | 283 | K>Q | No | 1000Genomes | |
| tmp_2_18342735_C_G | 289 | A>G | No | 1000Genomes | |
| ENSVATH13636464 | 324 | T>S | No | 1000Genomes | |
| tmp_2_18342938_G_C | 357 | D>H | No | 1000Genomes | |
| ENSVATH05715810 | 422 | N>K | No | 1000Genomes | |
| tmp_2_18343412_C_A | 425 | F>L | No | 1000Genomes | |
| ENSVATH05715815 | 505 | N>K | No | 1000Genomes | |
| ENSVATH14614589 | 505 | N>S | No | 1000Genomes |
No associated diseases with O64879
1 regional properties for O64879
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| conserved_site | Glycosyl hydrolases family 1, N-terminal conserved site | 40 - 54 | IPR033132 |
Functions
| Description | ||
|---|---|---|
| EC Number | 3.2.1.21 | Glycosidases, ie enzymes hydrolyzing O- and S-glycosyl compounds |
| Subcellular Localization |
|
|
| PANTHER Family | ||
| PANTHER Subfamily | ||
| PANTHER Protein Class | ||
| PANTHER Pathway Category | No pathway information available | |
4 GO annotations of cellular component
| Name | Definition |
|---|---|
| apoplast | The cell membranes and intracellular regions in a plant are connected through plasmodesmata, and plants may be described as having two major compartments: the living symplast and the non-living apoplast. The apoplast is external to the plasma membrane and includes cell walls, intercellular spaces and the lumen of dead structures such as xylem vessels. Water and solutes pass freely through it. |
| Golgi apparatus | A membrane-bound cytoplasmic organelle of the endomembrane system that further processes the core oligosaccharides (e.g. N-glycans) added to proteins in the endoplasmic reticulum and packages them into membrane-bound vesicles. The Golgi apparatus operates at the intersection of the secretory, lysosomal, and endocytic pathways. |
| plant-type cell wall | A more or less rigid stucture lying outside the cell membrane of a cell and composed of cellulose and pectin and other organic and inorganic substances. |
| plasmodesma | A fine cytoplasmic channel, found in all higher plants, that connects the cytoplasm of one cell to that of an adjacent cell. |
2 GO annotations of molecular function
| Name | Definition |
|---|---|
| beta-glucosidase activity | Catalysis of the hydrolysis of terminal, non-reducing beta-D-glucose residues with release of beta-D-glucose. |
| scopolin beta-glucosidase activity | Catalysis of the reaction: H2O + scopolin <=> beta-D-glucose + scopoletin. |
5 GO annotations of biological process
| Name | Definition |
|---|---|
| carbohydrate metabolic process | The chemical reactions and pathways involving carbohydrates, any of a group of organic compounds based of the general formula Cx(H2O)y. |
| glucosinolate catabolic process | The chemical reactions and pathways resulting in the breakdown of glucosinolates, substituted thioglucosides found in rapeseed products and related cruciferae. |
| kaempferol O-glucoside metabolic process | The chemical reactions and pathways involving O-glucosylated derivatives of kaempferol. |
| quercetin O-glucoside metabolic process | The chemical reactions and pathways involving O-glucosylated derivatives of quercetin. |
| response to salt stress | Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating an increase or decrease in the concentration of salt (particularly but not exclusively sodium and chloride ions) in the environment. |
5 homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| P11988 | bglB | 6-phospho-beta-glucosidase BglB | Escherichia coli (strain K12) | PR |
| Q46829 | bglA | 6-phospho-beta-glucosidase BglA | Escherichia coli (strain K12) | PR |
| Q3E8E5 | TGG3 | Putative myrosinase 3 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q9LKR7 | BGLU24 | Beta-glucosidase 24 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q8GXT2 | BGLU29 | Beta-glucosidase 29 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| 10 | 20 | 30 | 40 | 50 | 60 |
| MRGNYLSLLV | VLIVLASNDV | LANNNSSTPK | LRRSDFPEDF | IFGSATSAYQ | VEGGAHEDGR |
| 70 | 80 | 90 | 100 | 110 | 120 |
| GPSIWDTFSE | KYPEKIKDGS | NGSVADNSYH | LYKEDVALLH | QIGFNAYRFS | ISWSRILPRG |
| 130 | 140 | 150 | 160 | 170 | 180 |
| NLKGGINQAG | IDYYNNLINE | LLSKGIKPFA | TMFHWDTPQA | LEDAYGGFRG | AEIVNDFRDY |
| 190 | 200 | 210 | 220 | 230 | 240 |
| ADICFKNFGD | RVKHWMTLNE | PLTVVQQGYV | AGVMAPGRCS | KFTNPNCTDG | NGATEPYIVG |
| 250 | 260 | 270 | 280 | 290 | 300 |
| HNLILSHGAA | VQVYREKYKA | SQQGQVGIAL | NAGWNLPYTE | SPKDRLAAAR | AMAFTFDYFM |
| 310 | 320 | 330 | 340 | 350 | 360 |
| EPLVTGKYPV | DMVNNVKGRL | PIFTAQQSKM | LKGSYDFIGI | NYYSSTYAKD | VPCSTKDVTM |
| 370 | 380 | 390 | 400 | 410 | 420 |
| FSDPCASVTG | ERDGVPIGPK | AASDWLLIYP | KGIRDLVLYA | KYKFKDPVMY | ITENGRDEFS |
| 430 | 440 | 450 | 460 | 470 | 480 |
| TNKIFLKDGD | RIDYYARHLE | MVQDAISVGA | NVKGFFAWSL | LDNFEWAMGY | TVRFGLVYVD |
| 490 | 500 | ||||
| FKDGCKRYPK | KSAEWFRKLL | NEKKND |