P11988

PR
Gene name
bglB (b3721, JW3699)
Protein name
6-phospho-beta-glucosidase BglB
Names
Phospho-beta-glucosidase B
Species
Escherichia coli (strain K12)
KEGG Pathway
eco:b3721
EC number
3.2.1.86: Glycosidases, ie enzymes hydrolyzing O- and S-glycosyl compounds
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-70 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for P11988

Entry ID Method Resolution Chain Position Source
AF-P11988-F1 Predicted AlphaFoldDB

No variants for P11988

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for P11988

No associated diseases with P11988

2 regional properties for P11988

Type Name Position InterPro Accession
active_site Glycoside hydrolase family 1, active site 357 - 365 IPR018120
conserved_site Glycosyl hydrolases family 1, N-terminal conserved site 8 - 22 IPR033132

Functions

Description
EC Number 3.2.1.86 Glycosidases, ie enzymes hydrolyzing O- and S-glycosyl compounds
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
cytosol The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.

4 GO annotations of molecular function

Name Definition
6-phospho-beta-glucosidase activity Catalysis of the reaction: 6-phospho-beta-D-glucoside-(1,4)-D-glucose + H2O = D-glucose 6-phosphate + glucose.
beta-glucosidase activity Catalysis of the hydrolysis of terminal, non-reducing beta-D-glucose residues with release of beta-D-glucose.
hydrolase activity, hydrolyzing O-glycosyl compounds Catalysis of the hydrolysis of any O-glycosyl bond.
methyl beta-D-glucoside 6-phosphate glucohydrolase activity Catalysis of the reaction: methyl beta-D-glucoside 6-phosphate + H2O = beta-D-glucose 6-phosphate + methanol.

1 GO annotations of biological process

Name Definition
carbohydrate catabolic process The chemical reactions and pathways resulting in the breakdown of carbohydrates, any of a group of organic compounds based of the general formula Cx(H2O)y.

4 homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
Q3E8E5 TGG3 Putative myrosinase 3 Arabidopsis thaliana (Mouse-ear cress) PR
O64879 BGLU15 Beta-glucosidase 15 Arabidopsis thaliana (Mouse-ear cress) PR
Q8GXT2 BGLU29 Beta-glucosidase 29 Arabidopsis thaliana (Mouse-ear cress) PR
Q9LKR7 BGLU24 Beta-glucosidase 24 Arabidopsis thaliana (Mouse-ear cress) PR
10 20 30 40 50 60
MKAFPETFLW GGATAANQVE GAWQEDGKGI STSDLQPHGV MGKMEPRILG KENIKDVAID
70 80 90 100 110 120
FYHRYPEDIA LFAEMGFTCL RISIAWARIF PQGDEVEPNE AGLAFYDRLF DEMAQAGIKP
130 140 150 160 170 180
LVTLSHYEMP YGLVKNYGGW ANRAVIDHFE HYARTVFTRY QHKVALWLTF NEINMSLHAP
190 200 210 220 230 240
FTGVGLAEES GEAEVYQAIH HQLVASARAV KACHSLLPEA KIGNMLLGGL VYPLTCQPQD
250 260 270 280 290 300
MLQAMEENRR WMFFGDVQAR GQYPGYMQRF FRDHNITIEM TESDAEDLKH TVDFISFSYY
310 320 330 340 350 360
MTGCVSHDES INKNAQGNIL NMIPNPHLKS SEWGWQIDPV GLRVLLNTLW DRYQKPLFIV
370 380 390 400 410 420
ENGLGAKDSV EADGSIQDDY RIAYLNDHLV QVNEAIADGV DIMGYTSWGP IDLVSASHSQ
430 440 450 460
MSKRYGFIYV DRDDNGEGSL TRTRKKSFGW YAEVIKTRGL SLKKITIKAP