Q3E8E5
Gene name |
TGG3 |
Protein name |
Putative myrosinase 3 |
Names |
Beta-glucosidase 39, AtBGLU39, Sinigrinase 3, Thioglucosidase 3 |
Species |
Arabidopsis thaliana (Mouse-ear cress) |
KEGG Pathway |
ath:AT5G48375 |
EC number |
3.2.1.147: Glycosidases, ie enzymes hydrolyzing O- and S-glycosyl compounds |
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q3E8E5
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q3E8E5-F1 | Predicted | AlphaFoldDB |
61 variants for Q3E8E5
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| ENSVATH14610868 | 3 | F>C | No | 1000Genomes | |
| tmp_5_19603874_G_T | 4 | R>S | No | 1000Genomes | |
| tmp_5_19603833_G_T | 17 | C>* | No | 1000Genomes | |
| ENSVATH12629663 | 19 | A>S | No | 1000Genomes | |
| tmp_5_19603816_G_A | 23 | T>M | No | 1000Genomes | |
| ENSVATH12629662 | 26 | E>Q | No | 1000Genomes | |
| tmp_5_19603774_C_G | 37 | R>P | No | 1000Genomes | |
| ENSVATH03388761 | 56 | G>R | No | 1000Genomes | |
| ENSVATH14610867 | 66 | R>L | No | 1000Genomes | |
| ENSVATH07370552 | 74 | D>E | No | 1000Genomes | |
| tmp_5_19603433_C_T | 74 | D>N | No | 1000Genomes | |
| tmp_5_19603428_T_G | 75 | L>F | No | 1000Genomes | |
| ENSVATH14610865 | 85 | Y>H | No | 1000Genomes | |
| ENSVATH14610843 | 98 | L>I | No | 1000Genomes | |
| ENSVATH14610842 | 113 | A>T | No | 1000Genomes | |
| tmp_5_19603110_C_A | 120 | A>S | No | 1000Genomes | |
| ENSVATH00719151 | 123 | K>R | No | 1000Genomes | |
| ENSVATH07370547 | 130 | D>Y | No | 1000Genomes | |
| ENSVATH12629626 | 135 | K>M | No | 1000Genomes | |
| ENSVATH14610841 | 141 | V>I | No | 1000Genomes | |
| tmp_5_19602878_C_G | 166 | D>H | No | 1000Genomes | |
| ENSVATH07370544 | 167 | D>E | No | 1000Genomes | |
| ENSVATH00719150 | 185 | K>N | No | 1000Genomes | |
| tmp_5_19602816_C_T | 186 | W>* | No | 1000Genomes | |
| ENSVATH07370541 | 211 | I>S | No | 1000Genomes | |
| tmp_5_19602681_T_G | 214 | H>P | No | 1000Genomes | |
| ENSVATH07370539 | 225 | H>D | No | 1000Genomes | |
| tmp_5_19602632_T_A | 230 | K>N | No | 1000Genomes | |
| ENSVATH12629580 | 232 | K>N | No | 1000Genomes | |
| ENSVATH14610840 | 237 | G>E | No | 1000Genomes | |
| ENSVATH00719144 | 238 | Q>E | No | 1000Genomes | |
| ENSVATH07370535 | 239 | I>F | No | 1000Genomes | |
| ENSVATH07370534 | 239 | I>N | No | 1000Genomes | |
| ENSVATH07370532 | 262 | E>Q | No | 1000Genomes | |
| tmp_5_19602286_C_T | 291 | R>Q | No | 1000Genomes | |
| ENSVATH12629539 | 303 | L>F | No | 1000Genomes | |
| ENSVATH07370528 | 310 | F>S | No | 1000Genomes | |
| tmp_5_19602185_G_A | 325 | P>S | No | 1000Genomes | |
| tmp_5_19602176_G_T | 328 | P>T | No | 1000Genomes | |
| ENSVATH07370526 | 331 | R>I | No | 1000Genomes | |
| tmp_5_19602150_A_C | 336 | N>K | No | 1000Genomes | |
| ENSVATH07370524 | 341 | A>G | No | 1000Genomes | |
| ENSVATH07370523 | 344 | Y>H | No | 1000Genomes | |
| tmp_5_19601983_C_G | 354 | W>S | No | 1000Genomes | |
| ENSVATH07370518 | 358 | D>G | No | 1000Genomes | |
| ENSVATH12629452 | 365 | G>A | No | 1000Genomes | |
| tmp_5_19601821_T_A | 376 | K>* | No | 1000Genomes | |
| tmp_5_19601810_G_C | 379 | N>K | No | 1000Genomes | |
| tmp_5_19601806_A_C,ATGGG | 381 | L>V | No | 1000Genomes | |
| ENSVATH00719137 | 384 | I>F | No | 1000Genomes | |
| ENSVATH12629445 | 405 | C>S | No | 1000Genomes | |
| tmp_5_19601406_A_T | 406 | L>H | No | 1000Genomes | |
| ENSVATH09539462 | 418 | F>I | No | 1000Genomes | |
| ENSVATH09539460 | 422 | P>L | No | 1000Genomes | |
| ENSVATH09539460 | 422 | P>R | No | 1000Genomes | |
| ENSVATH09539461 | 422 | P>S | No | 1000Genomes | |
| ENSVATH09539459 | 426 | L>F | No | 1000Genomes | |
| ENSVATH09539457 | 435 | P>L | No | 1000Genomes | |
| tmp_5_19601314_A_G | 437 | F>L | No | 1000Genomes | |
| ENSVATH09539455 | 438 | E>* | No | 1000Genomes | |
| ENSVATH09539434 | 438 | E>D | No | 1000Genomes |
No associated diseases with Q3E8E5
Functions
| Description | ||
|---|---|---|
| EC Number | 3.2.1.147 | Glycosidases, ie enzymes hydrolyzing O- and S-glycosyl compounds |
| Subcellular Localization |
|
|
| PANTHER Family | ||
| PANTHER Subfamily | ||
| PANTHER Protein Class | ||
| PANTHER Pathway Category | No pathway information available | |
2 GO annotations of cellular component
| Name | Definition |
|---|---|
| plastid | Any member of a family of organelles found in the cytoplasm of plants and some protists, which are membrane-bounded and contain DNA. Plant plastids develop from a common type, the proplastid. |
| secretory vesicle | A cytoplasmic, membrane bound vesicle that is capable of fusing to the plasma membrane to release its contents into the extracellular space. |
3 GO annotations of molecular function
| Name | Definition |
|---|---|
| beta-glucosidase activity | Catalysis of the hydrolysis of terminal, non-reducing beta-D-glucose residues with release of beta-D-glucose. |
| glucosinolate glucohydrolase activity | Catalysis of the reaction: H2O + a glucosinolate = alpha-D-glucose + a thiohydroximate-O-sulfate. Glucosinolates are a subclass of thioglucosides. |
| thioglucosidase activity | Catalysis of the reaction: a thioglucoside + H2O = a thiol + a sugar. |
1 GO annotations of biological process
| Name | Definition |
|---|---|
| carbohydrate metabolic process | The chemical reactions and pathways involving carbohydrates, any of a group of organic compounds based of the general formula Cx(H2O)y. |
5 homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| P11988 | bglB | 6-phospho-beta-glucosidase BglB | Escherichia coli (strain K12) | PR |
| Q46829 | bglA | 6-phospho-beta-glucosidase BglA | Escherichia coli (strain K12) | PR |
| O64879 | BGLU15 | Beta-glucosidase 15 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q9LKR7 | BGLU24 | Beta-glucosidase 24 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q8GXT2 | BGLU29 | Beta-glucosidase 29 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| 10 | 20 | 30 | 40 | 50 | 60 |
| MKFRALGLVL | LLAVETCKAE | EITCEETKPF | TCNQTDRFNR | KHFDDDFIFE | GGKGRGLNVW |
| 70 | 80 | 90 | 100 | 110 | 120 |
| DGFTHRYPEK | GGPDLGNGDS | TCGSYEHWQK | DIDVMTELGV | DGYRFSLAWS | RIAPRESNQA |
| 130 | 140 | 150 | 160 | 170 | 180 |
| GVKYYNDLID | GLLAKNITPF | VTLFHWDLPQ | VLQDEYEGFL | NHEIIDDFKD | YANLCFKIFG |
| 190 | 200 | 210 | 220 | 230 | 240 |
| DRVKKWITIN | QLYTVPTRGY | AMGTDAPEPY | IVAHNQLLAH | AKVVHLYRKK | YKPKQRGQIG |
| 250 | 260 | 270 | 280 | 290 | 300 |
| VVMITRWFVP | YDSTQANIDA | TERNKEFFLG | WFMEPLTKGK | YPDIMRKLVG | RRLPKFNKKE |
| 310 | 320 | 330 | 340 | 350 | 360 |
| AKLVKGSYDF | LGINYYQTQY | VYAIPANPPN | RLTVLNDSLS | AFSYENKDGP | IGPWFNADSY |
| 370 | 380 | 390 | 400 | 410 | 420 |
| YHPRGILNVL | EHFKTKYGNP | LVYITENGEL | LILSGCNVKG | YFAWCLGDNY | ELWPSRSFHV |
| 430 | |||||
| SPFYLLHRKD | KGAFPSFEA |