Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

Autoinhibited structure

Activated structure

1 structures for Q8GXT2

Entry ID Method Resolution Chain Position Source
AF-Q8GXT2-F1 Predicted AlphaFoldDB

36 variants for Q8GXT2

Variant ID(s) Position Change Description Diseaes Association Provenance
ENSVATH05716068 2 N>K No 1000Genomes
tmp_2_18354280_T_C 8 L>P No 1000Genomes
tmp_2_18354283_T_C 9 L>P No 1000Genomes
tmp_2_18354345_G_T 30 D>Y No 1000Genomes
ENSVATH05716069 32 S>N No 1000Genomes
ENSVATH05716101 96 I>M No 1000Genomes
ENSVATH05716102 101 V>M No 1000Genomes
ENSVATH14614727 103 A>V No 1000Genomes
tmp_2_18355484_G_A 136 D>N No 1000Genomes
tmp_2_18355671_G_A 163 G>S No 1000Genomes
ENSVATH14614731 187 D>E No 1000Genomes
ENSVATH13637035 204 A>S No 1000Genomes
ENSVATH14614732 222 S>T No 1000Genomes
ENSVATH05716120 253 N>S No 1000Genomes
ENSVATH01987652 255 N>I No 1000Genomes
ENSVATH13637036 262 K>N No 1000Genomes
ENSVATH05716129 280 S>P No 1000Genomes
ENSVATH13637039 352 I>V No 1000Genomes
ENSVATH00274756 354 H>P No 1000Genomes
tmp_2_18356652_G_C 360 R>T No 1000Genomes
ENSVATH05716134 398 N>K No 1000Genomes
ENSVATH05716135 402 D>N No 1000Genomes
ENSVATH05716166 491 Q>R No 1000Genomes
ENSVATH05716167 515 T>K No 1000Genomes
ENSVATH14614764 525 R>H No 1000Genomes
ENSVATH01987672 529 K>N No 1000Genomes
tmp_2_18358310_A_G 538 E>G No 1000Genomes
ENSVATH00274759 541 K>N No 1000Genomes
tmp_2_18358322_C_A 542 T>N No 1000Genomes
ENSVATH00274760 542 T>S No 1000Genomes
tmp_2_18358340_T_A 548 V>D No 1000Genomes
tmp_2_18358356_C_A 553 N>K No 1000Genomes
tmp_2_18358401_C_A 568 F>L No 1000Genomes
ENSVATH05716169 576 D>E No 1000Genomes
ENSVATH05716170 577 Q>E No 1000Genomes
ENSVATH05716171 589 G>E No 1000Genomes

No associated diseases with Q8GXT2

2 regional properties for Q8GXT2

Type Name Position InterPro Accession
binding_site Aminotransferases, class-I, pyridoxal-phosphate-binding site 268 - 281 IPR004838
domain Aminotransferase, class I/classII 55 - 437 IPR004839

Functions

Description
EC Number 3.2.1.21 Glycosidases, ie enzymes hydrolyzing O- and S-glycosyl compounds
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

No GO annotations of cellular component

Name Definition
No GO annotations for cellular component

2 GO annotations of molecular function

Name Definition
beta-glucosidase activity Catalysis of the hydrolysis of terminal, non-reducing beta-D-glucose residues with release of beta-D-glucose.
scopolin beta-glucosidase activity Catalysis of the reaction: H2O + scopolin <=> beta-D-glucose + scopoletin.

3 GO annotations of biological process

Name Definition
carbohydrate metabolic process The chemical reactions and pathways involving carbohydrates, any of a group of organic compounds based of the general formula Cx(H2O)y.
glucosinolate catabolic process The chemical reactions and pathways resulting in the breakdown of glucosinolates, substituted thioglucosides found in rapeseed products and related cruciferae.
response to salt stress Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating an increase or decrease in the concentration of salt (particularly but not exclusively sodium and chloride ions) in the environment.

5 homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
P11988 bglB 6-phospho-beta-glucosidase BglB Escherichia coli (strain K12) PR
Q46829 bglA 6-phospho-beta-glucosidase BglA Escherichia coli (strain K12) PR
O64879 BGLU15 Beta-glucosidase 15 Arabidopsis thaliana (Mouse-ear cress) PR
Q3E8E5 TGG3 Putative myrosinase 3 Arabidopsis thaliana (Mouse-ear cress) PR
Q9LKR7 BGLU24 Beta-glucosidase 24 Arabidopsis thaliana (Mouse-ear cress) PR
10 20 30 40 50 60
MNVQIFILLL IISWLTPKIT SLPPESQVLD RSSFPDDFVF GTAISAFQSE GATSEGGKSP
70 80 90 100 110 120
TIWDYFSHTF PERTNMQNAD VAVDFYHRYK DDIKLIEELN VDAFRFSISW ARLIPSGKVK
130 140 150 160 170 180
DGVNKEGVQF YKALIDELIA NGIQPSVTLY HWDHPQALED EYGGFLNPQI IEDFRNFARV
190 200 210 220 230 240
CFENFGDKVK MWTTINEPYV ISVAGYDTGI KAVGRCSKWV NSRCQAGDSA IEPYIVSHHL
250 260 270 280 290 300
LLSHAAAVQE FRNCNKTLQD GKIGIVISPW WLEPYDSTSS ADKEAVERGL PLELEWHLNP
310 320 330 340 350 360
VIYGDYPETM KKHVGNRLPA FTPEQSKMLI NSSDFIGVNY YSIHFTAHLP HIDHTRPRFR
370 380 390 400 410 420
TDHHFEKKLI NRSNHETGPG DDRGKIHSHP EGLRRVLNYI KDKYNNPIVY VKENGIDHYD
430 440 450 460 470 480
DGTKSRETIL KDTFRISYHQ DHLKQVHKAI IEDGCDVRGY YVWSLFDNFE WEHGYNSRFG
490 500 510 520 530 540
MYYVDFKNNL QRYPKDSVNW FKKFLSRPVV RSEETEDEKV CNVSRKEEKI NKALDVSEGF
550 560 570 580
KTSVDSIVNL IKNGSRIEEE DDEEERDFCA FKNHNDQLGF FLKLQNSLGF