Q8GXT2
Gene name |
BGLU29 |
Protein name |
Beta-glucosidase 29 |
Names |
AtBGLU29 |
Species |
Arabidopsis thaliana (Mouse-ear cress) |
KEGG Pathway |
ath:AT2G44470 |
EC number |
3.2.1.21: Glycosidases, ie enzymes hydrolyzing O- and S-glycosyl compounds |
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q8GXT2
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q8GXT2-F1 | Predicted | AlphaFoldDB |
36 variants for Q8GXT2
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| ENSVATH05716068 | 2 | N>K | No | 1000Genomes | |
| tmp_2_18354280_T_C | 8 | L>P | No | 1000Genomes | |
| tmp_2_18354283_T_C | 9 | L>P | No | 1000Genomes | |
| tmp_2_18354345_G_T | 30 | D>Y | No | 1000Genomes | |
| ENSVATH05716069 | 32 | S>N | No | 1000Genomes | |
| ENSVATH05716101 | 96 | I>M | No | 1000Genomes | |
| ENSVATH05716102 | 101 | V>M | No | 1000Genomes | |
| ENSVATH14614727 | 103 | A>V | No | 1000Genomes | |
| tmp_2_18355484_G_A | 136 | D>N | No | 1000Genomes | |
| tmp_2_18355671_G_A | 163 | G>S | No | 1000Genomes | |
| ENSVATH14614731 | 187 | D>E | No | 1000Genomes | |
| ENSVATH13637035 | 204 | A>S | No | 1000Genomes | |
| ENSVATH14614732 | 222 | S>T | No | 1000Genomes | |
| ENSVATH05716120 | 253 | N>S | No | 1000Genomes | |
| ENSVATH01987652 | 255 | N>I | No | 1000Genomes | |
| ENSVATH13637036 | 262 | K>N | No | 1000Genomes | |
| ENSVATH05716129 | 280 | S>P | No | 1000Genomes | |
| ENSVATH13637039 | 352 | I>V | No | 1000Genomes | |
| ENSVATH00274756 | 354 | H>P | No | 1000Genomes | |
| tmp_2_18356652_G_C | 360 | R>T | No | 1000Genomes | |
| ENSVATH05716134 | 398 | N>K | No | 1000Genomes | |
| ENSVATH05716135 | 402 | D>N | No | 1000Genomes | |
| ENSVATH05716166 | 491 | Q>R | No | 1000Genomes | |
| ENSVATH05716167 | 515 | T>K | No | 1000Genomes | |
| ENSVATH14614764 | 525 | R>H | No | 1000Genomes | |
| ENSVATH01987672 | 529 | K>N | No | 1000Genomes | |
| tmp_2_18358310_A_G | 538 | E>G | No | 1000Genomes | |
| ENSVATH00274759 | 541 | K>N | No | 1000Genomes | |
| tmp_2_18358322_C_A | 542 | T>N | No | 1000Genomes | |
| ENSVATH00274760 | 542 | T>S | No | 1000Genomes | |
| tmp_2_18358340_T_A | 548 | V>D | No | 1000Genomes | |
| tmp_2_18358356_C_A | 553 | N>K | No | 1000Genomes | |
| tmp_2_18358401_C_A | 568 | F>L | No | 1000Genomes | |
| ENSVATH05716169 | 576 | D>E | No | 1000Genomes | |
| ENSVATH05716170 | 577 | Q>E | No | 1000Genomes | |
| ENSVATH05716171 | 589 | G>E | No | 1000Genomes |
No associated diseases with Q8GXT2
Functions
| Description | ||
|---|---|---|
| EC Number | 3.2.1.21 | Glycosidases, ie enzymes hydrolyzing O- and S-glycosyl compounds |
| Subcellular Localization |
|
|
| PANTHER Family | ||
| PANTHER Subfamily | ||
| PANTHER Protein Class | ||
| PANTHER Pathway Category | No pathway information available | |
No GO annotations of cellular component
| Name | Definition |
|---|---|
| No GO annotations for cellular component |
2 GO annotations of molecular function
| Name | Definition |
|---|---|
| beta-glucosidase activity | Catalysis of the hydrolysis of terminal, non-reducing beta-D-glucose residues with release of beta-D-glucose. |
| scopolin beta-glucosidase activity | Catalysis of the reaction: H2O + scopolin <=> beta-D-glucose + scopoletin. |
3 GO annotations of biological process
| Name | Definition |
|---|---|
| carbohydrate metabolic process | The chemical reactions and pathways involving carbohydrates, any of a group of organic compounds based of the general formula Cx(H2O)y. |
| glucosinolate catabolic process | The chemical reactions and pathways resulting in the breakdown of glucosinolates, substituted thioglucosides found in rapeseed products and related cruciferae. |
| response to salt stress | Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating an increase or decrease in the concentration of salt (particularly but not exclusively sodium and chloride ions) in the environment. |
5 homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| P11988 | bglB | 6-phospho-beta-glucosidase BglB | Escherichia coli (strain K12) | PR |
| Q46829 | bglA | 6-phospho-beta-glucosidase BglA | Escherichia coli (strain K12) | PR |
| O64879 | BGLU15 | Beta-glucosidase 15 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q3E8E5 | TGG3 | Putative myrosinase 3 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q9LKR7 | BGLU24 | Beta-glucosidase 24 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| 10 | 20 | 30 | 40 | 50 | 60 |
| MNVQIFILLL | IISWLTPKIT | SLPPESQVLD | RSSFPDDFVF | GTAISAFQSE | GATSEGGKSP |
| 70 | 80 | 90 | 100 | 110 | 120 |
| TIWDYFSHTF | PERTNMQNAD | VAVDFYHRYK | DDIKLIEELN | VDAFRFSISW | ARLIPSGKVK |
| 130 | 140 | 150 | 160 | 170 | 180 |
| DGVNKEGVQF | YKALIDELIA | NGIQPSVTLY | HWDHPQALED | EYGGFLNPQI | IEDFRNFARV |
| 190 | 200 | 210 | 220 | 230 | 240 |
| CFENFGDKVK | MWTTINEPYV | ISVAGYDTGI | KAVGRCSKWV | NSRCQAGDSA | IEPYIVSHHL |
| 250 | 260 | 270 | 280 | 290 | 300 |
| LLSHAAAVQE | FRNCNKTLQD | GKIGIVISPW | WLEPYDSTSS | ADKEAVERGL | PLELEWHLNP |
| 310 | 320 | 330 | 340 | 350 | 360 |
| VIYGDYPETM | KKHVGNRLPA | FTPEQSKMLI | NSSDFIGVNY | YSIHFTAHLP | HIDHTRPRFR |
| 370 | 380 | 390 | 400 | 410 | 420 |
| TDHHFEKKLI | NRSNHETGPG | DDRGKIHSHP | EGLRRVLNYI | KDKYNNPIVY | VKENGIDHYD |
| 430 | 440 | 450 | 460 | 470 | 480 |
| DGTKSRETIL | KDTFRISYHQ | DHLKQVHKAI | IEDGCDVRGY | YVWSLFDNFE | WEHGYNSRFG |
| 490 | 500 | 510 | 520 | 530 | 540 |
| MYYVDFKNNL | QRYPKDSVNW | FKKFLSRPVV | RSEETEDEKV | CNVSRKEEKI | NKALDVSEGF |
| 550 | 560 | 570 | 580 | ||
| KTSVDSIVNL | IKNGSRIEEE | DDEEERDFCA | FKNHNDQLGF | FLKLQNSLGF |