Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

Autoinhibited structure

Activated structure

1 structures for Q9FY66

Entry ID Method Resolution Chain Position Source
AF-Q9FY66-F1 Predicted AlphaFoldDB

18 variants for Q9FY66

Variant ID(s) Position Change Description Diseaes Association Provenance
ENSVATH06944284 4 V>I No 1000Genomes
ENSVATH03040265 6 P>Q No 1000Genomes
ENSVATH03040264 7 D>E No 1000Genomes
tmp_5_2953050_G_A 13 L>F No 1000Genomes
tmp_5_2952980_G_C 36 P>R No 1000Genomes
tmp_5_2952977_G_A 37 T>I No 1000Genomes
tmp_5_2952844_C_T 52 M>I No 1000Genomes
tmp_5_2952846_T_G 52 M>L No 1000Genomes
ENSVATH03040254 61 M>I No 1000Genomes
ENSVATH03040253 62 A>V No 1000Genomes
tmp_5_2952624_T_A 71 K>N No 1000Genomes
ENSVATH06944278 76 A>S No 1000Genomes
ENSVATH06944277 77 G>A No 1000Genomes
tmp_5_2952570_G_C 89 N>K No 1000Genomes
tmp_5_2952558_C_A 93 M>I No 1000Genomes
tmp_5_2952530_C_G 103 V>L No 1000Genomes
ENSVATH03040243 111 Q>P No 1000Genomes
tmp_5_2952490_G_T 116 P>Q No 1000Genomes

No associated diseases with Q9FY66

1 regional properties for Q9FY66

Type Name Position InterPro Accession
conserved_site Ribosomal protein S15/S19, conserved site 105 - 129 IPR020934

Functions

Description
EC Number
Subcellular Localization
  • Cytoplasm
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
cytosolic small ribosomal subunit The small subunit of a ribosome located in the cytosol.

2 GO annotations of molecular function

Name Definition
RNA binding Binding to an RNA molecule or a portion thereof.
structural constituent of ribosome The action of a molecule that contributes to the structural integrity of the ribosome.

2 GO annotations of biological process

Name Definition
ribosomal small subunit assembly The aggregation, arrangement and bonding together of constituent RNAs and proteins to form the small ribosomal subunit.
translation The cellular metabolic process in which a protein is formed, using the sequence of a mature mRNA or circRNA molecule to specify the sequence of amino acids in a polypeptide chain. Translation is mediated by the ribosome, and begins with the formation of a ternary complex between aminoacylated initiator methionine tRNA, GTP, and initiation factor 2, which subsequently associates with the small subunit of the ribosome and an mRNA or circRNA. Translation ends with the release of a polypeptide chain from the ribosome.

7 homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
Q01855 RPS15 40S ribosomal protein S15 Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) PR
P62841 RPS15 40S ribosomal protein S15 Homo sapiens (Human) PR
Q9FIX6 RPS15E 40S ribosomal protein S15-5 Arabidopsis thaliana (Mouse-ear cress) PR
Q9FML6 RPS15F 40S ribosomal protein S15-6 Arabidopsis thaliana (Mouse-ear cress) PR
Q9FY65 RPS15C 40S ribosomal protein S15-3 Arabidopsis thaliana (Mouse-ear cress) PR
Q08112 RPS15A 40S ribosomal protein S15-1 Arabidopsis thaliana (Mouse-ear cress) PR
Q9FY64 RPS15D 40S ribosomal protein S15-4 Arabidopsis thaliana (Mouse-ear cress) PR
10 20 30 40 50 60
MAEVEPDVSA AALAKKRTFK KFSFKGVDLD ALLDMPTDDL VELFPSRIRR RMSRGLTRKP
70 80 90 100 110 120
MALIKKLRKA KLDAPAGEKP EVVRTHLRNM VIMPEMIGSI IGVYNGKTFN QIEIKPEMIG
130 140 150
HYLAEFSITY KPVRHGKPGH GATHSSRFIP LK