Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

Autoinhibited structure

Activated structure

1 structures for Q9FIX6

Entry ID Method Resolution Chain Position Source
AF-Q9FIX6-F1 Predicted AlphaFoldDB

62 variants for Q9FIX6

Variant ID(s) Position Change Description Diseaes Association Provenance
ENSVATH03339329 3 P>L No 1000Genomes
ENSVATH03339329 3 P>Q No 1000Genomes
tmp_5_17531314_G_A 5 V>I No 1000Genomes
ENSVATH12457579 9 G>R No 1000Genomes
tmp_5_17531335_A_G 12 K>E No 1000Genomes
tmp_5_17531339_A_C 13 K>T No 1000Genomes
ENSVATH07320887 14 R>G No 1000Genomes
ENSVATH14579842 14 R>I No 1000Genomes
tmp_5_17531345_C_T 15 T>I No 1000Genomes
tmp_5_17531355_G_T 18 K>N No 1000Genomes
ENSVATH03339334 21 F>I No 1000Genomes
tmp_5_17531364_C_A 21 F>L No 1000Genomes
ENSVATH12457582 23 G>E No 1000Genomes
ENSVATH07320888 23 G>R No 1000Genomes
ENSVATH07320889 26 L>F No 1000Genomes
ENSVATH07320889 26 L>I No 1000Genomes
ENSVATH12457636 28 A>S No 1000Genomes
ENSVATH07320891 32 M>K No 1000Genomes
tmp_5_17531399_C_T 33 S>F No 1000Genomes
ENSVATH03339335 34 I>T No 1000Genomes
tmp_5_17531404_G_A 35 E>K No 1000Genomes
ENSVATH03339337 37 L>F No 1000Genomes
ENSVATH12457637 39 K>R No 1000Genomes
ENSVATH12457637 39 K>T No 1000Genomes
ENSVATH12457638 42 S>G No 1000Genomes
tmp_5_17531429_C_T 43 S>F No 1000Genomes
ENSVATH03339338 46 R>G No 1000Genomes
ENSVATH07320892 46 R>H No 1000Genomes
ENSVATH07320892 46 R>L No 1000Genomes
ENSVATH07320899 50 S>Y No 1000Genomes
ENSVATH07320900 51 R>K No 1000Genomes
ENSVATH00701987 54 T>S No 1000Genomes
ENSVATH03339342 55 R>I No 1000Genomes
ENSVATH03339342 55 R>K No 1000Genomes
ENSVATH12457642 57 P>L No 1000Genomes
tmp_5_17531553_C_T 57 P>S No 1000Genomes
ENSVATH07320901 58 M>I No 1000Genomes
ENSVATH07320902 59 A>D No 1000Genomes
ENSVATH03339343 59 A>T No 1000Genomes
ENSVATH07320902 59 A>V No 1000Genomes
tmp_5_17531562_T_A 60 L>M No 1000Genomes
ENSVATH03339345 65 R>C No 1000Genomes
ENSVATH12457696 65 R>P No 1000Genomes
ENSVATH14579844 67 A>T No 1000Genomes
ENSVATH07320920 69 M>I No 1000Genomes
ENSVATH12457807 75 E>D No 1000Genomes
ENSVATH07320921 79 S>A No 1000Genomes
tmp_5_17532165_C_T 82 T>I No 1000Genomes
ENSVATH03339361 87 M>I No 1000Genomes
ENSVATH12457808 91 P>S No 1000Genomes
ENSVATH07320924 102 N>I No 1000Genomes
tmp_5_17532228_G_T 103 G>V No 1000Genomes
ENSVATH07320925 109 V>L No 1000Genomes
ENSVATH00701994 110 E>A No 1000Genomes
tmp_5_17532270_G_A 117 G>E No 1000Genomes
ENSVATH14579870 123 F>Y No 1000Genomes
ENSVATH12457810 125 I>F No 1000Genomes
ENSVATH07320926 130 V>L No 1000Genomes
ENSVATH07320927 135 P>A No 1000Genomes
ENSVATH07320927 135 P>S No 1000Genomes
tmp_5_17532344_TC_GC,T 142 S>A No 1000Genomes
ENSVATH00701996 146 I>V No 1000Genomes

No associated diseases with Q9FIX6

1 regional properties for Q9FIX6

Type Name Position InterPro Accession
conserved_site Ribosomal protein S15/S19, conserved site 102 - 126 IPR020934

Functions

Description
EC Number
Subcellular Localization
  • Cytoplasm
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
cytosolic small ribosomal subunit The small subunit of a ribosome located in the cytosol.

2 GO annotations of molecular function

Name Definition
RNA binding Binding to an RNA molecule or a portion thereof.
structural constituent of ribosome The action of a molecule that contributes to the structural integrity of the ribosome.

2 GO annotations of biological process

Name Definition
ribosomal small subunit assembly The aggregation, arrangement and bonding together of constituent RNAs and proteins to form the small ribosomal subunit.
translation The cellular metabolic process in which a protein is formed, using the sequence of a mature mRNA or circRNA molecule to specify the sequence of amino acids in a polypeptide chain. Translation is mediated by the ribosome, and begins with the formation of a ternary complex between aminoacylated initiator methionine tRNA, GTP, and initiation factor 2, which subsequently associates with the small subunit of the ribosome and an mRNA or circRNA. Translation ends with the release of a polypeptide chain from the ribosome.

7 homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
Q01855 RPS15 40S ribosomal protein S15 Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) PR
P62841 RPS15 40S ribosomal protein S15 Homo sapiens (Human) PR
Q9FML6 RPS15F 40S ribosomal protein S15-6 Arabidopsis thaliana (Mouse-ear cress) PR
Q9FY65 RPS15C 40S ribosomal protein S15-3 Arabidopsis thaliana (Mouse-ear cress) PR
Q9FY66 RPS15B 40S ribosomal protein S15-2 Arabidopsis thaliana (Mouse-ear cress) PR
Q08112 RPS15A 40S ribosomal protein S15-1 Arabidopsis thaliana (Mouse-ear cress) PR
Q9FY64 RPS15D 40S ribosomal protein S15-4 Arabidopsis thaliana (Mouse-ear cress) PR
10 20 30 40 50 60
MEPEVVAAGI VKKRTFKKFS FRGVDLDALL DMSIEDLVKH FSSRIRRRFS RGLTRKPMAL
70 80 90 100 110 120
IKKLRKAKME APAGEKPASV RTHLRNMIIV PEMIGSIIGV YNGKTFNQVE IKPEMIGHYL
130 140
AEFSISYKPV KHGRPGVGAT NSSRFIPLK