Q9FML6

PR
Gene name
RPS15F (At5g63070, MDC12.3)
Protein name
40S ribosomal protein S15-6
Names
Species
Arabidopsis thaliana (Mouse-ear cress)
KEGG Pathway
ath:AT5G63070
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

40-111 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q9FML6

Entry ID Method Resolution Chain Position Source
AF-Q9FML6-F1 Predicted AlphaFoldDB

16 variants for Q9FML6

Variant ID(s) Position Change Description Diseaes Association Provenance
ENSVATH14646403 2 A>P No 1000Genomes
tmp_5_25299639_A_C 8 F>V No 1000Genomes
ENSVATH03467595 15 A>V No 1000Genomes
ENSVATH00748857 37 M>I No 1000Genomes
ENSVATH12914072 45 L>I No 1000Genomes
tmp_5_25299521_T_C 47 N>S No 1000Genomes
ENSVATH03467593 54 F>L No 1000Genomes
ENSVATH12914071 54 F>Y No 1000Genomes
ENSVATH00748856 78 D>E No 1000Genomes
tmp_5_25299342_C_G 107 V>L No 1000Genomes
ENSVATH12914070 109 N>S No 1000Genomes
tmp_5_25299283_A_C 126 Y>* No 1000Genomes
tmp_5_25299257_T_C 135 K>R No 1000Genomes
tmp_5_25299221_C_T 147 C>Y No 1000Genomes
ENSVATH03467589 149 C>F No 1000Genomes
tmp_5_25299216_A_G 149 C>R No 1000Genomes

No associated diseases with Q9FML6

1 regional properties for Q9FML6

Type Name Position InterPro Accession
conserved_site Ribosomal protein S15/S19, conserved site 109 - 133 IPR020934

Functions

Description
EC Number
Subcellular Localization
  • Cytoplasm
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
cytosolic small ribosomal subunit The small subunit of a ribosome located in the cytosol.

2 GO annotations of molecular function

Name Definition
RNA binding Binding to an RNA molecule or a portion thereof.
structural constituent of ribosome The action of a molecule that contributes to the structural integrity of the ribosome.

2 GO annotations of biological process

Name Definition
ribosomal small subunit assembly The aggregation, arrangement and bonding together of constituent RNAs and proteins to form the small ribosomal subunit.
translation The cellular metabolic process in which a protein is formed, using the sequence of a mature mRNA or circRNA molecule to specify the sequence of amino acids in a polypeptide chain. Translation is mediated by the ribosome, and begins with the formation of a ternary complex between aminoacylated initiator methionine tRNA, GTP, and initiation factor 2, which subsequently associates with the small subunit of the ribosome and an mRNA or circRNA. Translation ends with the release of a polypeptide chain from the ribosome.

7 homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
Q01855 RPS15 40S ribosomal protein S15 Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) PR
P62841 RPS15 40S ribosomal protein S15 Homo sapiens (Human) PR
Q9FIX6 RPS15E 40S ribosomal protein S15-5 Arabidopsis thaliana (Mouse-ear cress) PR
Q9FY65 RPS15C 40S ribosomal protein S15-3 Arabidopsis thaliana (Mouse-ear cress) PR
Q9FY66 RPS15B 40S ribosomal protein S15-2 Arabidopsis thaliana (Mouse-ear cress) PR
Q08112 RPS15A 40S ribosomal protein S15-1 Arabidopsis thaliana (Mouse-ear cress) PR
Q9FY64 RPS15D 40S ribosomal protein S15-4 Arabidopsis thaliana (Mouse-ear cress) PR
10 20 30 40 50 60
MAINEPEFAT AVAVATKKRT FKKFSFRGFN VDALLKMSNV DLAKLFNARV RRRFYRGLKK
70 80 90 100 110 120
QPLILIKKLR RAKKEASDEN KMKPEVVKTH LRNMIIVPEM IGSVVGVHNG KKFNEIVIKP
130 140 150
EMIGHYLAEF SMTCKKVNHH RPRICGCCCF RRSTRFIPLR