Q9CAS1

PR
Gene name
TRX8 (At1g69880, T17F3.9)
Protein name
Thioredoxin H8
Names
AtTrxh8
Species
Arabidopsis thaliana (Mouse-ear cress)
KEGG Pathway
ath:AT1G69880
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-64 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q9CAS1

Entry ID Method Resolution Chain Position Source
AF-Q9CAS1-F1 Predicted AlphaFoldDB

31 variants for Q9CAS1

Variant ID(s) Position Change Description Diseaes Association Provenance
ENSVATH00134626 7 T>S No 1000Genomes
ENSVATH00134627 9 D>E No 1000Genomes
ENSVATH01512082 20 T>R No 1000Genomes
ENSVATH01512083 22 P>S No 1000Genomes
ENSVATH00134628 26 R>Q No 1000Genomes
ENSVATH14458811 40 V>L No 1000Genomes
ENSVATH00134629 46 N>S No 1000Genomes
ENSVATH00134629 46 N>T No 1000Genomes
ENSVATH05114518 51 R>K No 1000Genomes
tmp_1_26321706_A_T 56 K>I No 1000Genomes
ENSVATH00134630 56 K>N No 1000Genomes
ENSVATH13780332 65 E>K No 1000Genomes
tmp_1_26322440_T_A 70 W>R No 1000Genomes
ENSVATH00134635 76 T>S No 1000Genomes
ENSVATH05114554 85 A>G No 1000Genomes
ENSVATH00134636 86 A>T No 1000Genomes
ENSVATH01512099 89 T>N No 1000Genomes
tmp_1_26322506_G_C 92 E>Q No 1000Genomes
tmp_1_26322512_G_C 94 V>L No 1000Genomes
ENSVATH05114555 95 K>M No 1000Genomes
tmp_1_26322521_G_C 97 D>H No 1000Genomes
ENSVATH13780333 98 V>A No 1000Genomes
ENSVATH14458855 100 V>A No 1000Genomes
tmp_1_26322657_G_A 104 V>M No 1000Genomes
ENSVATH01512107 111 S>N No 1000Genomes
ENSVATH14458856 127 M>I No 1000Genomes
ENSVATH01512108 127 M>R No 1000Genomes
tmp_1_26322729_G_A 128 V>I No 1000Genomes
tmp_1_26322736_G_A 130 G>D No 1000Genomes
ENSVATH00134641 136 L>F No 1000Genomes
tmp_1_26322753_T_G 136 L>V No 1000Genomes

No associated diseases with Q9CAS1

2 regional properties for Q9CAS1

Type Name Position InterPro Accession
domain Thioredoxin domain 1 - 145 IPR013766
conserved_site Thioredoxin, conserved site 63 - 81 IPR017937

Functions

Description
EC Number
Subcellular Localization
  • Cytoplasm
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.

No GO annotations of molecular function

Name Definition
No GO annotations for molecular function

No GO annotations of biological process

Name Definition
No GO annotations for biological process

8 homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
Q8N427 NME8 Thioredoxin domain-containing protein 3 Homo sapiens (Human) PR
Q8S091 Os01g0913000 Thioredoxin F, chloroplastic Oryza sativa subsp japonica (Rice) PR
Q6Z4I3 Os07g0190800 Thioredoxin H2-1 Oryza sativa subsp japonica (Rice) PR
Q9SIN1 TTL3 Inactive TPR repeat-containing thioredoxin TTL3 Arabidopsis thaliana (Mouse-ear cress) PR
Q8VWG7 TDX TPR repeat-containing thioredoxin TDX Arabidopsis thaliana (Mouse-ear cress) PR
Q84JR9 TTL4 TPR repeat-containing thioredoxin TTL4 Arabidopsis thaliana (Mouse-ear cress) PR
Q8VZT6 WCRKC2 Thioredoxin-like 3-2, chloroplastic Arabidopsis thaliana (Mouse-ear cress) PR
Q6NPF9 At1g76760 Thioredoxin Y1, chloroplastic Arabidopsis thaliana (Mouse-ear cress) PR
10 20 30 40 50 60
MGANVSTPDQ RFQVTHFRST KPWTPRPEIY PFKVNSPCIV EIKNMNQWKS RLNALKDTNK
70 80 90 100 110 120
LLVIEFTAKW CGPCKTLEPK LEELAAKYTD VEFVKIDVDV LMSVWMEFNL STLPAIVFMK
130 140
RGREVDMVVG VKVDELERKL NKYTQSFF