Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

Autoinhibited structure

Activated structure

2 structures for Q6NPF9

Entry ID Method Resolution Chain Position Source
7BZK X-ray 159 A B 63-172 PDB
AF-Q6NPF9-F1 Predicted AlphaFoldDB

12 variants for Q6NPF9

Variant ID(s) Position Change Description Diseaes Association Provenance
ENSVATH01545585 10 T>S No 1000Genomes
tmp_1_28812915_G_A 12 P>S No 1000Genomes
ENSVATH00145242 26 A>V No 1000Genomes
tmp_1_28812846_A_T 35 F>I No 1000Genomes
ENSVATH13821084 60 P>S No 1000Genomes
ENSVATH13821084 60 P>T No 1000Genomes
tmp_1_28812466_A_T 70 F>I No 1000Genomes
tmp_1_28812463_C_G 71 D>H No 1000Genomes
tmp_1_28812149_C_T 112 D>N No 1000Genomes
tmp_1_28812138_C_A 115 Q>H No 1000Genomes
ENSVATH05156993 125 P>R No 1000Genomes
tmp_1_28811877_G_C 172 P>R No 1000Genomes

No associated diseases with Q6NPF9

2 regional properties for Q6NPF9

Type Name Position InterPro Accession
domain Thioredoxin domain 5 - 169 IPR013766
conserved_site Thioredoxin, conserved site 85 - 103 IPR017937

Functions

Description
EC Number
Subcellular Localization
  • Plastid, chloroplast stroma
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

3 GO annotations of cellular component

Name Definition
chloroplast A chlorophyll-containing plastid with thylakoids organized into grana and frets, or stroma thylakoids, and embedded in a stroma.
chloroplast stroma The space enclosed by the double membrane of a chloroplast but excluding the thylakoid space. It contains DNA, ribosomes and some temporary products of photosynthesis.
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.

4 GO annotations of molecular function

Name Definition
enzyme activator activity Binds to and increases the activity of an enzyme.
oxidoreductase activity Catalysis of an oxidation-reduction (redox) reaction, a reversible chemical reaction in which the oxidation state of an atom or atoms within a molecule is altered. One substrate acts as a hydrogen or electron donor and becomes oxidized, while the other acts as hydrogen or electron acceptor and becomes reduced.
oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor Catalysis of an oxidation-reduction (redox) reaction in which a sulfur-containing group acts as a hydrogen or electron donor and reduces disulfide.
protein-disulfide reductase activity Catalysis of the reaction: a protein with reduced sulfide groups = a protein with oxidized disulfide bonds.

1 GO annotations of biological process

Name Definition
positive regulation of catalytic activity Any process that activates or increases the activity of an enzyme.

2 homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
Q9CAS1 TRX8 Thioredoxin H8 Arabidopsis thaliana (Mouse-ear cress) PR
Q8VZT6 WCRKC2 Thioredoxin-like 3-2, chloroplastic Arabidopsis thaliana (Mouse-ear cress) PR
10 20 30 40 50 60
MASISLSSST VPSLNSKESS GVSAFASRSI SAVKFQFPVR RVRTGDLKFP SLSSTTRCTP
70 80 90 100 110 120
RRIEAKKQTF DSFEDLLVNS DKPVLVDYYA TWCGPCQFMV PILNEVSETL KDKIQVVKID
130 140 150 160 170
TEKYPSIANK YKIEALPTFI LFKDGEPCDR FEGALTAKQL IQRIEDSLKV KP