Q8VZT6
Gene name |
WCRKC2 (At5g04260, F21E1_180) |
Protein name |
Thioredoxin-like 3-2, chloroplastic |
Names |
Thioredoxin WCRKC-2 |
Species |
Arabidopsis thaliana (Mouse-ear cress) |
KEGG Pathway |
ath:AT5G04260 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q8VZT6
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q8VZT6-F1 | Predicted | AlphaFoldDB |
22 variants for Q8VZT6
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| ENSVATH06920407 | 9 | S>P | No | 1000Genomes | |
| ENSVATH13917240 | 25 | Y>S | No | 1000Genomes | |
| ENSVATH00605936 | 27 | Q>L | No | 1000Genomes | |
| ENSVATH00605936 | 27 | Q>R | No | 1000Genomes | |
| ENSVATH10560477 | 28 | T>I | No | 1000Genomes | |
| ENSVATH03020581 | 31 | S>T | No | 1000Genomes | |
| ENSVATH06920405 | 33 | S>A | No | 1000Genomes | |
| ENSVATH06920404 | 33 | S>F | No | 1000Genomes | |
| ENSVATH13917239 | 34 | R>Q | No | 1000Genomes | |
| ENSVATH13917238 | 37 | N>K | No | 1000Genomes | |
| tmp_5_1179906_T_A | 39 | K>N | No | 1000Genomes | |
| ENSVATH10560476 | 42 | S>Y | No | 1000Genomes | |
| tmp_5_1179837_C_A | 62 | Q>H | No | 1000Genomes | |
| ENSVATH06920403 | 69 | L>R | No | 1000Genomes | |
| tmp_5_1179746_C_A | 93 | D>Y | No | 1000Genomes | |
| tmp_5_1179743_C_A | 94 | A>S | No | 1000Genomes | |
| ENSVATH00605935 | 97 | L>P | No | 1000Genomes | |
| ENSVATH00605935 | 97 | L>R | No | 1000Genomes | |
| tmp_5_1179722_C_T | 101 | V>I | No | 1000Genomes | |
| ENSVATH13917235 | 145 | L>H | No | 1000Genomes | |
| tmp_5_1179220_C_T | 148 | R>H | No | 1000Genomes | |
| tmp_5_1179215_C_T | 150 | G>R | No | 1000Genomes |
No associated diseases with Q8VZT6
1 regional properties for Q8VZT6
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| domain | Thioredoxin domain | 66 - 191 | IPR013766 |
1 GO annotations of cellular component
| Name | Definition |
|---|---|
| chloroplast stroma | The space enclosed by the double membrane of a chloroplast but excluding the thylakoid space. It contains DNA, ribosomes and some temporary products of photosynthesis. |
No GO annotations of molecular function
| Name | Definition |
|---|---|
| No GO annotations for molecular function |
1 GO annotations of biological process
| Name | Definition |
|---|---|
| cell redox homeostasis | Any process that maintains the redox environment of a cell or compartment within a cell. |
8 homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| Q8N427 | NME8 | Thioredoxin domain-containing protein 3 | Homo sapiens (Human) | PR |
| Q8S091 | Os01g0913000 | Thioredoxin F, chloroplastic | Oryza sativa subsp japonica (Rice) | PR |
| Q6Z4I3 | Os07g0190800 | Thioredoxin H2-1 | Oryza sativa subsp japonica (Rice) | PR |
| Q9SIN1 | TTL3 | Inactive TPR repeat-containing thioredoxin TTL3 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q8VWG7 | TDX | TPR repeat-containing thioredoxin TDX | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q84JR9 | TTL4 | TPR repeat-containing thioredoxin TTL4 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q9CAS1 | TRX8 | Thioredoxin H8 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q6NPF9 | At1g76760 | Thioredoxin Y1, chloroplastic | Arabidopsis thaliana (Mouse-ear cress) | PR |
| 10 | 20 | 30 | 40 | 50 | 60 |
| MSEIVNLSSS | LRSLNPKISP | LVPPYRQTSS | SFSRPRNFKY | HSFTDKICLA | AERIRAVDIQ |
| 70 | 80 | 90 | 100 | 110 | 120 |
| KQDGGLQELD | DSPVSVELGP | ICGESHFDQV | MEDAQKLGES | VVIVWMAAWC | RKCIYLKPKL |
| 130 | 140 | 150 | 160 | 170 | 180 |
| EKLAAEFYPR | LRFYHVDVNA | VPYRLVSRAG | VTKMPTIQLW | RDGQKQAEVI | GGHKAHFVVN |
| 190 | |||||
| EVREMIENDS | IT |