Q84JR9
PR
Gene name |
TTL4 (At3g58620, F14P22.210) |
Protein name |
TPR repeat-containing thioredoxin TTL4 |
Names |
Tetratricopeptide repeat thioredoxin-like 4 |
Species |
Arabidopsis thaliana (Mouse-ear cress) |
KEGG Pathway |
ath:AT3G58620 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q84JR9
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q84JR9-F1 | Predicted | AlphaFoldDB |
62 variants for Q84JR9
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| ENSVATH00426371 | 21 | L>M | No | 1000Genomes | |
| ENSVATH06339306 | 26 | D>E | No | 1000Genomes | |
| tmp_3_21680475_G_C | 27 | D>H | No | 1000Genomes | |
| tmp_3_21680518_G_A | 41 | G>D | No | 1000Genomes | |
| ENSVATH06339308 | 46 | P>L | No | 1000Genomes | |
| ENSVATH06339309 | 47 | R>H | No | 1000Genomes | |
| tmp_3_21680547_T_C | 51 | S>P | No | 1000Genomes | |
| ENSVATH12822726 | 55 | T>P | No | 1000Genomes | |
| ENSVATH06339310 | 82 | R>P | No | 1000Genomes | |
| tmp_3_21680662_C_A | 89 | S>Y | No | 1000Genomes | |
| tmp_3_21680672_C_A | 92 | S>R | No | 1000Genomes | |
| ENSVATH00426372 | 93 | Q>E | No | 1000Genomes | |
| tmp_3_21680700_G_A | 102 | V>M | No | 1000Genomes | |
| tmp_3_21680710_A_T | 105 | N>I | No | 1000Genomes | |
| tmp_3_21680833_C_T | 146 | S>L | No | 1000Genomes | |
| tmp_3_21680881_G_A | 162 | R>K | No | 1000Genomes | |
| tmp_3_21680901_G_T | 169 | A>S | No | 1000Genomes | |
| ENSVATH12822746 | 194 | T>I | No | 1000Genomes | |
| ENSVATH12822748 | 223 | R>K | No | 1000Genomes | |
| ENSVATH00426373 | 225 | G>E | No | 1000Genomes | |
| ENSVATH14452099 | 262 | E>D | No | 1000Genomes | |
| ENSVATH06339320 | 284 | R>S | No | 1000Genomes | |
| ENSVATH06339319 | 284 | R>T | No | 1000Genomes | |
| tmp_3_21681368_A_T | 301 | H>L | No | 1000Genomes | |
| tmp_3_21681387_A_T | 307 | Q>H | No | 1000Genomes | |
| ENSVATH06339322 | 312 | A>S | No | 1000Genomes | |
| ENSVATH12822752 | 332 | K>N | No | 1000Genomes | |
| ENSVATH06339323 | 339 | V>L | No | 1000Genomes | |
| ENSVATH06339324 | 345 | A>E | No | 1000Genomes | |
| ENSVATH06339326 | 358 | V>L | No | 1000Genomes | |
| ENSVATH02522277 | 372 | K>Q | No | 1000Genomes | |
| tmp_3_21681710_A_G | 383 | R>G | No | 1000Genomes | |
| tmp_3_21681729_C_G | 389 | T>S | No | 1000Genomes | |
| ENSVATH02522278 | 402 | A>T | No | 1000Genomes | |
| ENSVATH00426375 | 415 | L>F | No | 1000Genomes | |
| ENSVATH06339332 | 422 | I>V | No | 1000Genomes | |
| tmp_3_21681940_T_C | 425 | V>A | No | 1000Genomes | |
| tmp_3_21681939_G_T | 425 | V>L | No | 1000Genomes | |
| ENSVATH12822754 | 431 | I>M | No | 1000Genomes | |
| ENSVATH06339333 | 431 | I>V | No | 1000Genomes | |
| ENSVATH12822776 | 451 | K>N | No | 1000Genomes | |
| tmp_3_21682040_G_T | 458 | E>D | No | 1000Genomes | |
| ENSVATH06339336 | 462 | S>L | No | 1000Genomes | |
| tmp_3_21682074_G_T | 470 | V>L | No | 1000Genomes | |
| tmp_3_21682097_G_C | 477 | K>N | No | 1000Genomes | |
| ENSVATH14452103 | 491 | A>V | No | 1000Genomes | |
| tmp_3_21682155_G_A | 497 | G>S | No | 1000Genomes | |
| tmp_3_21682168_A_G | 501 | K>R | No | 1000Genomes | |
| tmp_3_21682174_T_C | 503 | V>A | No | 1000Genomes | |
| ENSVATH06339337 | 523 | R>S | No | 1000Genomes | |
| tmp_3_21682245_T_A | 527 | Y>N | No | 1000Genomes | |
| ENSVATH12822778 | 528 | G>E | No | 1000Genomes | |
| tmp_3_21682350_G_A | 537 | V>I | No | 1000Genomes | |
| ENSVATH06339340 | 550 | D>G | No | 1000Genomes | |
| ENSVATH00426377 | 558 | Q>E | No | 1000Genomes | |
| ENSVATH00426378 | 562 | N>T | No | 1000Genomes | |
| tmp_3_21682472_T_A | 577 | N>K | No | 1000Genomes | |
| ENSVATH02522285 | 586 | L>I | No | 1000Genomes | |
| tmp_3_21682636_A_C | 604 | K>Q | No | 1000Genomes | |
| tmp_3_21682813_G_A | 635 | V>I | No | 1000Genomes | |
| ENSVATH12822804 | 637 | E>K | No | 1000Genomes | |
| tmp_3_21682834_G_A | 642 | A>T | No | 1000Genomes |
No associated diseases with Q84JR9
8 regional properties for Q84JR9
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| repeat | Tetratricopeptide repeat 1 | 485 - 516 | IPR001440 |
| domain | Thioredoxin domain | 613 - 669 | IPR013766 |
| repeat | Tetratricopeptide repeat | 211 - 244 | IPR019734-1 |
| repeat | Tetratricopeptide repeat | 245 - 278 | IPR019734-2 |
| repeat | Tetratricopeptide repeat | 402 - 435 | IPR019734-3 |
| repeat | Tetratricopeptide repeat | 449 - 482 | IPR019734-4 |
| repeat | Tetratricopeptide repeat | 483 - 516 | IPR019734-5 |
| repeat | Tetratricopeptide repeat | 517 - 550 | IPR019734-6 |
2 GO annotations of cellular component
No GO annotations of molecular function
| Name | Definition |
|---|---|
| No GO annotations for molecular function |
1 GO annotations of biological process
| Name | Definition |
|---|---|
| response to osmotic stress | Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating an increase or decrease in the concentration of solutes outside the organism or cell. |
8 homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| Q8N427 | NME8 | Thioredoxin domain-containing protein 3 | Homo sapiens (Human) | PR |
| Q80ZX8 | Spag1 | Sperm-associated antigen 1 | Mus musculus (Mouse) | PR |
| Q8S091 | Os01g0913000 | Thioredoxin F, chloroplastic | Oryza sativa subsp japonica (Rice) | PR |
| Q6Z4I3 | Os07g0190800 | Thioredoxin H2-1 | Oryza sativa subsp japonica (Rice) | PR |
| Q9CAS1 | TRX8 | Thioredoxin H8 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q8VWG7 | TDX | TPR repeat-containing thioredoxin TDX | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q8VZT6 | WCRKC2 | Thioredoxin-like 3-2, chloroplastic | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q9SIN1 | TTL3 | Inactive TPR repeat-containing thioredoxin TTL3 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| 10 | 20 | 30 | 40 | 50 | 60 |
| MSHYRRHSLE | PSITSKFRDS | LSFQRDDDVI | NKPDFRELDF | GSPLRPRGSS | SAAATPAASG |
| 70 | 80 | 90 | 100 | 110 | 120 |
| SSSSSSGSAS | GKPAVTSQFA | RRSHSGELSG | LSQTSPVKPG | SVNRNLKPGH | RRSASAGTPL |
| 130 | 140 | 150 | 160 | 170 | 180 |
| IYSGLGFSPV | NNNNNSSRGG | GSGATSPNPG | VLPTGNICPS | GRILKTGMAT | RASVRPETLC |
| 190 | 200 | 210 | 220 | 230 | 240 |
| TGTANYGHGN | IIRTGGKVSH | ATKAAAEMSD | SEEVKKAGNV | MYRKGNYAEA | LALYDRAISL |
| 250 | 260 | 270 | 280 | 290 | 300 |
| SPENPAYRSN | RAAALAASGR | LEEAVKECLE | AVRCDPSYAR | AHQRLASLYL | RLGEAENARR |
| 310 | 320 | 330 | 340 | 350 | 360 |
| HLCVSGQCPD | QADLQRLQTL | EKHLRLCTEA | RKIGDWRTVI | SEIDAAIANG | ADSSPQLVAC |
| 370 | 380 | 390 | 400 | 410 | 420 |
| KAEAFLRLHQ | IKDSDLCISS | IPRLDHHHTQ | PPEKLFGIVC | DAYVLCVQAQ | VDMALGRFEN |
| 430 | 440 | 450 | 460 | 470 | 480 |
| AIVKVERAMT | IDHSNSPEVV | SVLNNVKNVA | KARTRGNELF | SSGRYSEASV | AYGDGLKLDA |
| 490 | 500 | 510 | 520 | 530 | 540 |
| FNSVLYCNRA | ACWFKLGMWE | KSVDDCNQAL | RIQPSYTKAL | LRRAASYGKL | GRWEDAVRDY |
| 550 | 560 | 570 | 580 | 590 | 600 |
| EVLRKELPGD | SEVAESLQRA | RNALSNKSEE | PKYLGFNNEV | EEVSTLDKFK | TATSLPGISV |
| 610 | 620 | 630 | 640 | 650 | 660 |
| FHFKSSSNRQ | SEAISPFVNT | LCLRYPLVHF | FKVDVEESLA | LAKAESIKKI | PTFKIYKKGE |
| 670 | 680 | ||||
| KVKEMVCPSH | QLLEDSVTHF | LL |