Q94JX9

PR
Gene name
At3g49470 (T9C5.70)
Protein name
Nascent polypeptide-associated complex subunit alpha-like protein 2
Names
NAC-alpha-like protein 2, Alpha-NAC-like protein 2
Species
Arabidopsis thaliana (Mouse-ear cress)
KEGG Pathway
ath:AT3G49470
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

7-100 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q94JX9

Entry ID Method Resolution Chain Position Source
AF-Q94JX9-F1 Predicted AlphaFoldDB

16 variants for Q94JX9

Variant ID(s) Position Change Description Diseaes Association Provenance
ENSVATH08150230 6 A>T No 1000Genomes
tmp_3_18341090_G_A 7 V>I No 1000Genomes
ENSVATH12663514 15 Q>K No 1000Genomes
ENSVATH02477024 23 A>P No 1000Genomes
tmp_3_18341143_T_G 24 I>M No 1000Genomes
ENSVATH12663545 25 A>V No 1000Genomes
ENSVATH06279088 31 K>T No 1000Genomes
ENSVATH06279108 63 V>L No 1000Genomes
tmp_3_18341726_G_T 64 S>I No 1000Genomes
tmp_3_18341803_G_T 90 G>C No 1000Genomes
tmp_3_18341830_A_C 99 T>P No 1000Genomes
tmp_3_18341932_T_C 105 F>L No 1000Genomes
ENSVATH12663563 126 A>T No 1000Genomes
ENSVATH02477029 155 A>V No 1000Genomes
ENSVATH06279117 157 A>V No 1000Genomes
tmp_3_18342167_T_C 183 I>T No 1000Genomes

No associated diseases with Q94JX9

2 regional properties for Q94JX9

Type Name Position InterPro Accession
domain Nascent polypeptide-associated complex NAC domain 70 - 135 IPR002715
domain Nascent polypeptide-associated complex subunit alpha-like, UBA domain 177 - 216 IPR044034

Functions

Description
EC Number
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

3 GO annotations of cellular component

Name Definition
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
cytosol The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
nascent polypeptide-associated complex A heterodimeric protein complex that can reversibly bind to ribosomes, and is located in direct proximity to newly synthesized polypeptide chains as they emerge from the ribosome.

2 GO annotations of molecular function

Name Definition
mRNA binding Binding to messenger RNA (mRNA), an intermediate molecule between DNA and protein. mRNA includes UTR and coding sequences, but does not contain introns.
unfolded protein binding Binding to an unfolded protein.

1 GO annotations of biological process

Name Definition
protein targeting to membrane The process of directing proteins towards a membrane, usually using signals contained within the protein.

6 homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
Q5E9A1 NACA Nascent polypeptide-associated complex subunit alpha Bos taurus (Bovine) PR
Q94518 Nacalpha Nascent polypeptide-associated complex subunit alpha Drosophila melanogaster (Fruit fly) PR
Q13765 NACA Nascent polypeptide-associated complex subunit alpha Homo sapiens (Human) PR
Q9BZK3 NACA4P Putative nascent polypeptide-associated complex subunit alpha-like protein Homo sapiens (Human) PR
Q86S66 icd-2 Nascent polypeptide-associated complex subunit alpha Caenorhabditis elegans PR
Q68F90 naca Nascent polypeptide-associated complex subunit alpha Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) PR
10 20 30 40 50 60
MSPPPAVVTE SADGQPEQPP VTAIAEELEK KLQTDEPIVE DVKDDEDDDD DDEEEEDDDA
70 80 90 100 110 120
QGVSGSSKQS RSEKKSRKAM LKLGMKPVTG VSRVTIKRTK NVLFFISKPD VFKSPHSETY
130 140 150 160 170 180
VIFGEAKIED LSSQLQTQAA QQFRMPEIGA TSQRAEASTA TVEAQVEEDE EEIDETGVEA
190 200 210
RDIDLVMTQA GVSRSKAVKA LKSHDGDIVS AIMELTT