Q920M5
Gene name |
Coro6 |
Protein name |
Coronin-6 |
Names |
Coronin-like protein E, Clipin-E |
Species |
Mus musculus (Mouse) |
KEGG Pathway |
mmu:216961 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q920M5
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q920M5-F1 | Predicted | AlphaFoldDB |
27 variants for Q920M5
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| rs3389180407 | 81 | T>S | No | EVA | |
| rs3389176913 | 92 | H>Y | No | EVA | |
| rs3389192056 | 110 | Q>H | No | EVA | |
| rs3389145611 | 141 | P>L | No | EVA | |
| rs3389189311 | 171 | D>A | No | EVA | |
| rs3389177804 | 225 | A>S | No | EVA | |
| rs3389177817 | 258 | V>M | No | EVA | |
| rs3389181745 | 260 | L>Q | No | EVA | |
| rs3389145609 | 261 | Q>R | No | EVA | |
| rs3402553945 | 281 | V>L | No | EVA | |
| rs3389117950 | 289 | S>C | No | EVA | |
| rs3389177802 | 304 | H>D | No | EVA | |
| rs3402232775 | 311 | S>L | No | EVA | |
| rs3389189327 | 314 | P>S | No | EVA | |
| rs3389189307 | 337 | Y>F | No | EVA | |
| rs3389169315 | 362 | L>R | No | EVA | |
| rs3389145659 | 367 | P>A | No | EVA | |
| rs3389185717 | 373 | L>Q | No | EVA | |
| rs3389182989 | 419 | P>S | No | EVA | |
| rs3389195049 | 421 | R>C | No | EVA | |
| rs3389192026 | 423 | Q>H | No | EVA | |
| rs3389194999 | 436 | E>G | No | EVA | |
| rs3389156083 | 439 | L>M | No | EVA | |
| rs231898673 | 441 | E>D | No | EVA | |
| rs215623923 | 447 | D>E | No | EVA | |
| rs3389185693 | 469 | G>V | No | EVA | |
| rs1133561570 | 471 | D>G | No | EVA |
No associated diseases with Q920M5
4 regional properties for Q920M5
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| domain | Cryptochrome/DNA photolyase, FAD-binding domain | 287 - 485 | IPR005101 |
| domain | DNA photolyase, N-terminal | 5 - 160 | IPR006050 |
| conserved_site | Cryptochrome/DNA photolyase class 1, conserved site, C-terminal | 336 - 348 | IPR018394-1 |
| conserved_site | Cryptochrome/DNA photolyase class 1, conserved site, C-terminal | 356 - 375 | IPR018394-2 |
No GO annotations of cellular component
| Name | Definition |
|---|---|
| No GO annotations for cellular component |
1 GO annotations of molecular function
| Name | Definition |
|---|---|
| actin filament binding | Binding to an actin filament, also known as F-actin, a helical filamentous polymer of globular G-actin subunits. |
2 GO annotations of biological process
| Name | Definition |
|---|---|
| actin filament organization | A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising actin filaments. Includes processes that control the spatial distribution of actin filaments, such as organizing filaments into meshworks, bundles, or other structures, as by cross-linking. |
| cell migration | The controlled self-propelled movement of a cell from one site to a destination guided by molecular cues. Cell migration is a central process in the development and maintenance of multicellular organisms. |
7 homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| Q06440 | CRN1 | Coronin-like protein | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) | PR |
| Q9ULV4 | CORO1C | Coronin-1C | Homo sapiens (Human) | PR |
| Q9UQ03 | CORO2B | Coronin-2B | Homo sapiens (Human) | PR |
| Q6QEF8 | CORO6 | Coronin-6 | Homo sapiens (Human) | PR |
| Q9D2V7 | Coro7 | Coronin-7 | Mus musculus (Mouse) | PR |
| Q9WUM3 | Coro1b | Coronin-1B | Mus musculus (Mouse) | PR |
| Q9WUM4 | Coro1c | Coronin-1C | Mus musculus (Mouse) | PR |
| 10 | 20 | 30 | 40 | 50 | 60 |
| MSRRVVRQSK | FRHVFGQAAK | ADQAYEDIRV | SKVTWDSAFC | AVNPKFLAII | VEAGGGGAFI |
| 70 | 80 | 90 | 100 | 110 | 120 |
| VLPLAKTGRV | DKNYPLVTGH | TGPVLDIDWC | PHNDNVIASA | SDDTTVMVWQ | IPDYTPVRNI |
| 130 | 140 | 150 | 160 | 170 | 180 |
| TEPVITLEGH | SKRVGILSWH | PTARNVLLSA | GGDNVIIIWN | VGTGEVLLSL | DDIHPDVIHS |
| 190 | 200 | 210 | 220 | 230 | 240 |
| VCWNSNGSLL | ATTCKDKTLR | IIDPRKSQVV | AERARPHEGA | RPLRAVFTAD | GKLLSTGFSR |
| 250 | 260 | 270 | 280 | 290 | 300 |
| MSERQLALWD | PNNFEEPVAL | QEMDTSNGVL | LPFYDPDSSI | VYLCGKGDSS | IRYFEITEEP |
| 310 | 320 | 330 | 340 | 350 | 360 |
| PFVHYLNTFS | SKEPQRGMGF | MPKRGLDVSK | CEIARFYKLH | ERKCEPIIMT | VPRKSDLFQD |
| 370 | 380 | 390 | 400 | 410 | 420 |
| DLYPDTPGPE | PALEADEWLS | GQDAEPVLIS | LKEGYVPPKH | RELRVTKRNI | LDVRPPASPR |
| 430 | 440 | 450 | 460 | 470 | |
| RSQSASEAPL | SQHTLETLLE | EIKALRDRVQ | AQEERITALE | NMLCELVDGT | D |