Q8QG60
Gene name |
CRY2 |
Protein name |
Cryptochrome-2 |
Names |
|
Species |
Gallus gallus (Chicken) |
KEGG Pathway |
gga:374092 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q8QG60
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q8QG60-F1 | Predicted | AlphaFoldDB |
No variants for Q8QG60
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for Q8QG60 | |||||
No associated diseases with Q8QG60
2 GO annotations of cellular component
| Name | Definition |
|---|---|
| cytoplasm | The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures. |
| nucleus | A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent. |
3 GO annotations of molecular function
| Name | Definition |
|---|---|
| DNA binding | Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid). |
| FAD binding | Binding to the oxidized form, FAD, of flavin-adenine dinucleotide, the coenzyme or the prosthetic group of various flavoprotein oxidoreductase enzymes. |
| photoreceptor activity | The function of absorbing and responding to incidental electromagnetic radiation, particularly visible light. The response may involve a change in conformation. |
7 GO annotations of biological process
| Name | Definition |
|---|---|
| circadian regulation of gene expression | Any process that modulates the frequency, rate or extent of gene expression such that an expression pattern recurs with a regularity of approximately 24 hours. |
| circadian rhythm | Any biological process in an organism that recurs with a regularity of approximately 24 hours. |
| entrainment of circadian clock by photoperiod | The synchronization of a circadian rhythm to photoperiod, the intermittent cycle of light (day) and dark (night). |
| negative regulation of circadian rhythm | Any process that stops, prevents, or reduces the frequency, rate or extent of a circadian rhythm behavior. |
| negative regulation of DNA-templated transcription | Any process that stops, prevents, or reduces the frequency, rate or extent of cellular DNA-templated transcription. |
| regulation of circadian rhythm | Any process that modulates the frequency, rate or extent of a circadian rhythm. A circadian rhythm is a biological process in an organism that recurs with a regularity of approximately 24 hours. |
| response to light stimulus | Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a light stimulus, electromagnetic radiation of wavelengths classified as infrared, visible or ultraviolet light. |
8 homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| Q16526 | CRY1 | Cryptochrome-1 | Homo sapiens (Human) | PR |
| Q49AN0 | CRY2 | Cryptochrome-2 | Homo sapiens (Human) | PR |
| P97784 | Cry1 | Cryptochrome-1 | Mus musculus (Mouse) | PR |
| Q9R194 | Cry2 | Cryptochrome-2 | Mus musculus (Mouse) | PR |
| Q923I8 | Cry2 | Cryptochrome-2 | Rattus norvegicus (Rat) | PR |
| Q0E2Y1 | UVR3 | (6-4)DNA photolyase | Oryza sativa subsp japonica (Rice) | PR |
| Q96524 | CRY2 | Cryptochrome-2 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| O48652 | UVR3 | (6-4)DNA photolyase | Arabidopsis thaliana (Mouse-ear cress) | PR |
| 10 | 20 | 30 | 40 | 50 | 60 |
| MAAAASPPRG | FCRSVHWFRR | GLRLHDNPAL | QAALRGAASL | RCIYILDPWF | AASSAVGINR |
| 70 | 80 | 90 | 100 | 110 | 120 |
| WRFLLQSLED | LDNSLRKLNS | RLFVVRGQPT | DVFPRLFKEW | GVTRLAFEYD | SEPFGKERDA |
| 130 | 140 | 150 | 160 | 170 | 180 |
| AIIKLAKEAG | VEVVIENSHT | LYNLDRIIEL | NGNKPPLTYK | RFQAIISRME | LPKKPVSSIV |
| 190 | 200 | 210 | 220 | 230 | 240 |
| SQQMETCKVD | IQENHDDVYG | VPSLEELGFP | TDGLAPAVWQ | GGETEALARL | DKHLERKAWV |
| 250 | 260 | 270 | 280 | 290 | 300 |
| ANYERPRMNA | NSLLASPTGL | SPYLRFGCLS | CRLFYYRLWE | LYKKVKRNST | PPLSLYGQLL |
| 310 | 320 | 330 | 340 | 350 | 360 |
| WREFFYTAAT | NNPKFDRMEG | NPICIQIPWD | KNPEALAKWA | EGKTGFPWID | AIMTQLRQEG |
| 370 | 380 | 390 | 400 | 410 | 420 |
| WIHHLARHAV | ACFLTRGDLW | ISWESGVRVF | DELLLDADFS | VNAGSWMWLS | CSAFFQQFFH |
| 430 | 440 | 450 | 460 | 470 | 480 |
| CYCPVGFGRR | TDPSGDYVKR | YLPKLKGFPS | RYIYEPWNAP | ESVQKAAKCI | IGVDYPKPMV |
| 490 | 500 | 510 | 520 | 530 | 540 |
| NHAETSRLNI | ERMKQIYQQL | SRYRGLCLLA | SVPSCVEDLS | GPVTDSAPGQ | GSSTSTAVRL |
| 550 | 560 | 570 | 580 | ||
| PQSDQASPKR | KHEGAEELCT | EELYKRAKVT | GLPAPEIPGK | SS |