Q7XMK8
Gene name |
Os04g0533000 (LOC_Os04g45040, OsJ_15580, OSJNBb0039L24.10) |
Protein name |
DEAD-box ATP-dependent RNA helicase 6 |
Names |
|
Species |
Oryza sativa subsp japonica (Rice) |
KEGG Pathway |
osa:4336501 |
EC number |
3.6.4.13: Acting on ATP; involved in cellular and subcellular movement |
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q7XMK8
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q7XMK8-F1 | Predicted | AlphaFoldDB |
No variants for Q7XMK8
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for Q7XMK8 | |||||
No associated diseases with Q7XMK8
No regional properties for Q7XMK8
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| No domain, repeats, and functional sites for Q7XMK8 | |||
Functions
| Description | ||
|---|---|---|
| EC Number | 3.6.4.13 | Acting on ATP; involved in cellular and subcellular movement |
| Subcellular Localization |
|
|
| PANTHER Family | ||
| PANTHER Subfamily | ||
| PANTHER Protein Class | ||
| PANTHER Pathway Category | No pathway information available | |
2 GO annotations of cellular component
| Name | Definition |
|---|---|
| cytoplasmic stress granule | A dense aggregation in the cytosol composed of proteins and RNAs that appear when the cell is under stress. |
| P-body | A focus in the cytoplasm where mRNAs may become inactivated by decapping or some other mechanism. Protein and RNA localized to these foci are involved in mRNA degradation, nonsense-mediated mRNA decay (NMD), translational repression, and RNA-mediated gene silencing. |
4 GO annotations of molecular function
| Name | Definition |
|---|---|
| ATP binding | Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator. |
| ATP hydrolysis activity | Catalysis of the reaction: ATP + H2O = ADP + H+ phosphate. ATP hydrolysis is used in some reactions as an energy source, for example to catalyze a reaction or drive transport against a concentration gradient. |
| mRNA binding | Binding to messenger RNA (mRNA), an intermediate molecule between DNA and protein. mRNA includes UTR and coding sequences, but does not contain introns. |
| RNA helicase activity | Unwinding of an RNA helix, driven by ATP hydrolysis. |
5 GO annotations of biological process
| Name | Definition |
|---|---|
| mRNA processing | Any process involved in the conversion of a primary mRNA transcript into one or more mature mRNA(s) prior to translation into polypeptide. |
| mRNA transport | The directed movement of mRNA, messenger ribonucleic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. |
| negative regulation of translation | Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of proteins by the translation of mRNA or circRNA. |
| P-body assembly | The aggregation, arrangement and bonding together of proteins and RNA molecules to form a cytoplasmic mRNA processing body. |
| stress granule assembly | The aggregation, arrangement and bonding together of proteins and RNA molecules to form a stress granule. |
10 homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| P39517 | DHH1 | ATP-dependent RNA helicase DHH1 | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) | PR |
| Q5ZKB9 | DDX6 | Probable ATP-dependent RNA helicase DDX6 | Gallus gallus (Chicken) | PR |
| P26196 | DDX6 | Probable ATP-dependent RNA helicase DDX6 | Homo sapiens (Human) | PR |
| P54823 | Ddx6 | Probable ATP-dependent RNA helicase DDX6 | Mus musculus (Mouse) | PR |
| Q109G2 | Os10g0503700 | DEAD-box ATP-dependent RNA helicase 12 | Oryza sativa subsp japonica (Rice) | PR |
| Q6H7S2 | Os02g0641800 | DEAD-box ATP-dependent RNA helicase 8 | Oryza sativa subsp japonica (Rice) | PR |
| Q94BV4 | RH6 | DEAD-box ATP-dependent RNA helicase 6 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q9M2E0 | RH12 | DEAD-box ATP-dependent RNA helicase 12 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q8RXK6 | RH8 | DEAD-box ATP-dependent RNA helicase 8 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q0IHV9 | ddx6 | Probable ATP-dependent RNA helicase ddx6 | Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) | PR |
| 10 | 20 | 30 | 40 | 50 | 60 |
| MDPRARYPPG | IGNGRGGNPN | YYGRGPPPSQ | HQQHQHQHQQ | PPHPHHHQYV | QRQPQPQQTP |
| 70 | 80 | 90 | 100 | 110 | 120 |
| HNSQHQQWLR | RNQIAAEAAG | ASEQKAPPVA | DGIDSSSQDW | KAQLKLPPQD | TRYRTEDVTA |
| 130 | 140 | 150 | 160 | 170 | 180 |
| TKGNEFEDYF | LKRELLMGIY | EKGFERPSPI | QEESIPIALT | GSDILARAKN | GTGKTAAFCI |
| 190 | 200 | 210 | 220 | 230 | 240 |
| PALEKIDQDK | NAIQVVILVP | TRELALQTSQ | VCKELGKHLK | IQVMVTTGGT | SLKDDIVRLY |
| 250 | 260 | 270 | 280 | 290 | 300 |
| QPVHLLVGTP | GRILDLTKKG | VCVLKNCSML | VMDEADKLLS | PEFQPSIQEL | IRYLPSNRQI |
| 310 | 320 | 330 | 340 | 350 | 360 |
| LMFSATFPVT | VKEFKDKYLP | KPYVINLMDE | LTLKGITQFY | AFVEERQKVH | CLNTLFSKLQ |
| 370 | 380 | 390 | 400 | 410 | 420 |
| INQSIIFCNS | VNRVELLAKK | ITELGYSCFY | IHAKMLQDHR | NRVFHDFRNG | ACRNLVCTDL |
| 430 | 440 | 450 | 460 | 470 | 480 |
| FTRGIDIQAV | NVVINFDFPK | SAETYLHRVG | RSGRFGHLGL | AVNLITYEDR | FNLYRIEQEL |
| 490 | |||||
| GTEIKPIPPQ | IDRAIYCQ |