| actin cytoskeleton organization |
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising actin filaments and their associated proteins. |
| actin filament capping |
The binding of a protein or protein complex to the end of an actin filament, thus preventing the addition, exchange or removal of further actin subunits. |
| actin filament depolymerization |
Disassembly of actin filaments by the removal of actin monomers from a filament. |
| actin filament polymerization |
Assembly of actin filaments by the addition of actin monomers to a filament. |
| actin filament reorganization |
A process that is carried out at the cellular level which results in dynamic structural changes to the arrangement of actin filaments. |
| actin filament severing |
The process in which an actin filament is broken down into smaller filaments. |
| actin nucleation |
The initial step in the formation of an actin filament, in which actin monomers combine to form a new filament. Nucleation is slow relative to the subsequent addition of more monomers to extend the filament. |
| actin polymerization or depolymerization |
Assembly or disassembly of actin filaments by the addition or removal of actin monomers from a filament. |
| aging |
A developmental process that is a deterioration and loss of function over time. Aging includes loss of functions such as resistance to disease, homeostasis, and fertility, as well as wear and tear. Aging includes cellular senescence, but is more inclusive. May precede death and may succeed developmental maturation (GO:0021700). |
| amyloid fibril formation |
The generation of amyloid fibrils, insoluble fibrous protein aggregates exhibiting beta sheet structure, from proteins. |
| apoptotic process |
A programmed cell death process which begins when a cell receives an internal (e.g. DNA damage) or external signal (e.g. an extracellular death ligand), and proceeds through a series of biochemical events (signaling pathway phase) which trigger an execution phase. The execution phase is the last step of an apoptotic process, and is typically characterized by rounding-up of the cell, retraction of pseudopodes, reduction of cellular volume (pyknosis), chromatin condensation, nuclear fragmentation (karyorrhexis), plasma membrane blebbing and fragmentation of the cell into apoptotic bodies. When the execution phase is completed, the cell has died. |
| barbed-end actin filament capping |
The binding of a protein or protein complex to the barbed (or plus) end of an actin filament, thus preventing the addition, exchange or removal of further actin subunits. |
| cardiac muscle cell contraction |
The actin filament-based process in which cytoplasmic actin filaments slide past one another resulting in contraction of a cardiac muscle cell. |
| cell projection assembly |
Formation of a prolongation or process extending from a cell, e.g. a flagellum or axon. |
| cellular response to cadmium ion |
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cadmium (Cd) ion stimulus. |
| cellular response to interferon-gamma |
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interferon-gamma stimulus. Interferon gamma is the only member of the type II interferon found so far. |
| central nervous system development |
The process whose specific outcome is the progression of the central nervous system over time, from its formation to the mature structure. The central nervous system is the core nervous system that serves an integrating and coordinating function. In vertebrates it consists of the brain and spinal cord. In those invertebrates with a central nervous system it typically consists of a brain, cerebral ganglia and a nerve cord. |
| cilium assembly |
The assembly of a cilium, a specialized eukaryotic organelle that consists of a filiform extrusion of the cell surface. Each cilium is bounded by an extrusion of the cytoplasmic membrane, and contains a regular longitudinal array of microtubules, anchored basally in a centriole. |
| hepatocyte apoptotic process |
Any apoptotic process in a hepatocyte, the main structural component of the liver. |
| negative regulation of viral entry into host cell |
Any process that stops, prevents, or reduces the frequency, rate or extent of the entry of viral entry into a host cell. |
| oligodendrocyte development |
The process aimed at the progression of an oligodendrocyte over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell. An oligodendrocyte is a type of glial cell involved in myelinating the axons in the central nervous system. |
| phagocytosis, engulfment |
The internalization of bacteria, immune complexes and other particulate matter or of an apoptotic cell by phagocytosis, including the membrane and cytoskeletal processes required, which involves one of three mechanisms: zippering of pseudopods around a target via repeated receptor-ligand interactions, sinking of the target directly into plasma membrane of the phagocytosing cell, or induced uptake via an enhanced membrane ruffling of the phagocytosing cell similar to macropinocytosis. |
| phosphatidylinositol-mediated signaling |
The series of molecular signals in which a cell uses a phosphatidylinositol-mediated signaling to convert a signal into a response. Phosphatidylinositols include phosphatidylinositol (PtdIns) and its phosphorylated derivatives. |
| positive regulation of actin nucleation |
Any process that activates or increases the frequency, rate or extent of actin nucleation, the initial step in the formation of an actin filament in which actin monomers combine to form a new filament. |
| positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway |
Any process that activates or increases the frequency, rate or extent of cysteine-type endopeptidase activity involved in apoptotic signaling pathway. |
| positive regulation of gene expression |
Any process that increases the frequency, rate or extent of gene expression. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product (protein or RNA). |
| positive regulation of keratinocyte apoptotic process |
Any process that activates or increases the frequency, rate or extent of keratinocyte apoptotic process. |
| positive regulation of protein processing in phagocytic vesicle |
Any process that activates or increases the frequency, rate or extent of protein processing in phagocytic vesicle. |
| protein destabilization |
Any process that decreases the stability of a protein, making it more vulnerable to degradative processes or aggregation. |
| regulation of cell adhesion |
Any process that modulates the frequency, rate or extent of attachment of a cell to another cell or to the extracellular matrix. |
| regulation of establishment of T cell polarity |
Any process that modulates the frequency, rate or extent of establishment of T cell polarity. |
| regulation of plasma membrane raft polarization |
Any process that modulates the frequency, rate or extent of plasma membrane raft polarization. |
| regulation of podosome assembly |
Any process that modulates the frequency, rate or extent of podosome assembly. |
| regulation of receptor clustering |
Any process that modulates the frequency, rate or extent of receptor clustering. |
| relaxation of cardiac muscle |
The process in which the extent of cardiac muscle contraction is reduced. |
| renal protein absorption |
A renal system process in which proteins are taken up from the collecting ducts, glomerulus and proximal and distal loops of the nephron. In non-mammalian species, absorption may occur in related structures (e.g. protein absorption is observed in nephrocytes in Drosophila, see PMID:23264686). |
| response to ethanol |
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an ethanol stimulus. |
| response to folic acid |
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a folic acid stimulus. |
| response to muscle stretch |
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a myofibril being extended beyond its slack length. |
| sequestering of actin monomers |
The selective interaction of actin monomers with specific molecules that inhibit their polymerization by preventing their access to other monomers. |
| striated muscle atrophy |
A process, occurring in striated muscle, that is characterized by a decrease in protein content, fiber diameter, force production and fatigue resistance in response to different conditions such as starvation, aging and disuse. |
| tissue regeneration |
The regrowth of lost or destroyed tissues. |
| vesicle-mediated transport |
A cellular transport process in which transported substances are moved in membrane-bounded vesicles; transported substances are enclosed in the vesicle lumen or located in the vesicle membrane. The process begins with a step that directs a substance to the forming vesicle, and includes vesicle budding and coating. Vesicles are then targeted to, and fuse with, an acceptor membrane. |
| wound healing |
The series of events that restore integrity to a damaged tissue, following an injury. |
